Myoblasts
Mostrando 1-12 de 449 artigos, teses e dissertações.
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1. Generation of Yellow Fever virus vaccine in skeletal muscle cells of chicken embryos
BACKGROUND The Yellow Fever (YF) vaccine is produced by the inoculation of embryonated chicken eggs with YF17DD virus on the ninth day of development. Full embryos are collected on the twelfth day of development for vaccine formulation. Skeletal muscle tissue is the main site where biosynthesis of viral particles occurs. OBJECTIVES This study aimed to an
Mem. Inst. Oswaldo Cruz. Publicado em: 09/12/2019
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2. The E3 ligase MuRF2 plays a key role in the functional capacity of skeletal muscle fibroblasts
Fibroblasts are a highly heterogeneous population of cells, being found in a large number of different tissues. These cells produce the extracellular matrix, which is essential to preserve structural integrity of connective tissues. Fibroblasts are frequently engaged in migration and remodeling, exerting traction forces in the extracellular matrix, which is
Braz J Med Biol Res. Publicado em: 29/08/2019
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3. Ethanol extract of Prunus mume fruit attenuates hydrogen peroxide-induced oxidative stress and apoptosis involving Nrf2/HO-1 activation in C2C12 myoblasts
ABSTRACT The fruit of the Prunus mume (Siebold) Siebold & Zucc., Rosaceae (Korean name: Maesil) has long been used as a health food or valuable medicinal material in traditional herb medicine in Southeast Asian countries. In this study, we determined the potential therapeutic efficacy of the ethanol extract of P. mume fruits (EEPM) against H2O2-induced oxida
Rev. bras. farmacogn.. Publicado em: 2016-04
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4. Six1 induces protein synthesis signaling expression in duck myoblasts mainly via up-regulation of mTOR
Abstract As a critical transcription factor, Six1 plays an important role in the regulation of myogenesis and muscle development. However, little is known about its regulatory mechanism associated with muscular protein synthesis. The objective of this study was to investigate the effects of overexpression ofSix1 on the expression of key protein metabolism-re
Genet. Mol. Biol.. Publicado em: 2016-03
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5. Small activating RNA induces myogenic differentiation of rat adipose-derived stem cells by upregulating MyoD
ABSTRACTPurpose:RNA activation (RNAa) is a mechanism of gene activation triggered by promoter-targeted small double stranded RNAs (dsRNAs), also known as small activating RNAs (saRNAs). Myogenic regulatory factor MyoD is regarded as the master activator of myogenic differentiation cascade by binding to enhancer of muscle specific genes. Stress urinary incont
Int. braz j urol.. Publicado em: 2015-08
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6. Avaliação dos efeitos do laser em baixa intensidade e do ultrassom terapêutico sobre a proliferação e diferenciação de células precursoras miogênicas. / Evaluation of the effect of the laser in low intensity and ultrassom therapeutical on the proliferation and differentiation of miogênicas precursory cells.
O objetivo do estudo foi analisar o efeito do laser em baixa intensidade (LBI) e do ultrassom terapêutico (US) sobre a proliferação e diferenciação de mioblastos C2C12. Os mioblastos foram cultivados em meio de cultura Eagle modificado por Dulbecco (DMEM) contendo 10% de soro fetal bovino (SFB) e induzidos à diferenciação pela substituição do meio
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 07/12/2011
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7. Death switch for gene therapy: application to erythropoietin transgene expression
The effectiveness of the caspase-9-based artificial "death switch" as a safety measure for gene therapy based on the erythropoietin (Epo) hormone was tested in vitro and in vivo using the chemical inducer of dimerization, AP20187. Plasmids encoding the dimeric murine Epo, the tetracycline-controlled transactivator and inducible caspase 9 (ptet-mEpoD, ptet-tT
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-07
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8. Efeito do anabolizante decanoato de nadrolona na viabilidade, proliferação, adesão e diferenciação em células musculares C2C12. / Effect of the anabolizante decanoato of nadrolona in the viability, proliferation, adhesion and differentiation in muscular cells C2C12.
Estudos apontam que o anabolizante decanoato de nandrolona modula a regulação do ciclo celular, porém pouco se conhece sobre seus efeitos nas células musculares. Assim, o objetivo foi avaliar o efeito do anabolizante decanoato de nandrolona na proliferação, adesão e diferenciação das células musculares C2C12. As células foram cultivadas em meio re
Publicado em: 2010
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9. ALT-C, a disintegrin-like Cys-rich protein from Bothrops alternatus, increases skeletal myoblast viability
ALT-C, an ECD motif (glutamic acid, cysteine, aspartic acid) disintegrin from Bothrops alternatus snake venom, induces α2β1 integrin-mediated signaling and neutrophil chemotaxis. In vitro, in human umbilical vein endothelial cells (HUVEC), ALT-C induces cell proliferation, thus showing an interesting potential for tissue regeneration studies. This work aim
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2009
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10. Ação da laserterapia de baixa intensidade (830nm) na regeneração muscular de ratos idosos
The elderly still go through physical changes, especially musculoskeletal disorders such as sarcopenia, changes in central and peripheral nervous system, blood hypoperfusion, regenerative changes contributing to atrophy and muscle weakness, undermining the activities of daily living (AVL). The regenerative process happens about the determination, proliferati
Publicado em: 2009
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11. Alteration in endogenous proteolytic pathways caused by Bothrops Jararacussu venom in skeletal muscle / Alterações nas vias proteoliticas endogenas causados pela peçonha de Bothrops Jararacussu em musculo esqueletico
Bites by Bothrops snakes produce intense local hemorrhage and myonecrosis, often with extensive tissue degradation. In this work, we investigated the activities of the proteasome (pathway for selective protein degradation), cathepsins (lysosomal proteinases) and calpains (neutral, calcium-dependent proteinases) in envenoming by Bothrops jararacussu. We also
Publicado em: 2008
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12. Changes in cell shape and desmin intermediate filament distribution are associated with down-regulation of desmin expression in C2C12 myoblasts grown in the absence of extracellular Ca2+
Desmin is the main intermediate filament (IF) protein of muscle cells. In skeletal muscle, desmin IFs form a scaffold that interconnects the entire contractile apparatus with the subsarcolemmal cytoskeleton and cytoplasmic organelles. The interaction between desmin and the sarcolemma is mediated by a number of membrane proteins, many of which are Ca2+-sensit
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-07