Mutagenic Activity
Mostrando 25-36 de 298 artigos, teses e dissertações.
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25. Avaliação do potencial mutagênico, recombinogênico e carcinogênico do Orlistat em células somáticas de Drosophila melanogaster
CHAPTER 2: Orlistat is the first compound of a new pharmacological class which limits dietary fat absorption by inhibiting gastric and pancreatic lipases. It does not affect the neuronal circuits regulating appetite, and its action consists basically of obstructing digestion of dietary triglycerides. Recent researches suggest that orlistat stops the growth o
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 26/07/2011
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26. Analysis of antimicrobial, cytotoxic and mutagenic potencial of extracts and substances obteined of diferente species of Piper / Análise do potencial antimicrobiano, citotóxico e mutagênico de extratos e substâncias obtidas de diferentes espécies de Piper
The infectious diseases are now one of the major causes of death in all over the world. The appearance of emerging infectious diseases and the problem of microbial resistance has driven the research for new antimicrobial agents. A thousand of years the medicinal plants has been used by your properties of healing. From this utilization scientific studies has
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/02/2011
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27. The antigenotoxic activity of latex from Himatanthus articulatus
Himatanthus articulatus (Vahl) Woodson (Apocynaceae) is a native plant to the Amazon popularly used to treat ulcers, tumors, inflammations, cancer, syphilis and malaria. The aim of the present study was to investigate the in vivo genotoxic/antigenotoxic and mutagenic potential of this plant, using the comet and the micronucleus assays in mice. Female and mal
Revista Brasileira de Farmacognosia. Publicado em: 29/11/2011
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28. Assessment of estrogenic, mutagenic and antimutagenic activity of nemorosone
Currently, a wide range of research involving natural products is focused on the discovery of new drugs in many different therapeutic areas. A great number of the synthetic compounds on the market were derived from natural products, especially plants. Nemorosone is the major constituent of the floral resin of Clusia rosea Jacq., Clusiaceae, and in Cuban prop
Revista Brasileira de Farmacognosia. Publicado em: 26/08/2011
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29. Antitumoral, mutagenic and (anti)estrogenic activities of tingenone and pristimerin
Cancer constitutes the second main mortality cause in the world, after cardiovascular diseases. In spite of the progresses in the chemotherapeutics treatments, many patients fail chemotherapy, mainly because of side effects or multi-drugs resistance, proving the need and importance of the research for new molecules with anticancer activity, more effective an
Revista Brasileira de Farmacognosia. Publicado em: 26/08/2011
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30. Mutagenicity induced by the hydroalcoholic extract of the medicinal plant Plathymenia reticulata Benth
Plathymenia reticulata Benth has an anti-inflammatory effect and is capable of neutralizing the neuromuscular blockade induced by Bothrops jararacussu or Crotalus durissus terrificus venoms, probably by precipitating venom proteins (an effect caused by plant tannins). The present study aimed to evaluate the mutagenic activity of P. reticulata by using the Sa
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2011
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31. Enhanced production of alkaline protease by a mutant of Bacillus licheniformis N-2 for dehairing
The purpose of the present investigations was to improve the yield of alkaline protease for leather dehairing by subjecting the indigenous proteolytic strain Bacillus licheniformis N-2 to various mutagenic treatments viz. UV irradiations, NTG (N-methyl-N-nitro-N-nitrosoguinidine) and MMS (methyl methane sulfonate). After screening on skim milk agar plates, a
Brazilian Archives of Biology and Technology. Publicado em: 2010-10
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32. Avaliação da atividade antimicrobiana, mutagênica e toxicidade aguda de derivados anfifílicos da o-carboximetilquitosana / Evaluation of antimicrobial, mutagenic activity and acute toxicity of amphifilic derivatives of O-carboxymethylchitosan
The chitosan (Ch), a semi-synthetic derivative biopolymer obtained by deacetylation of chitin, has attracted the attention of researchers due to its multiple bioactivities such as hemostasis, antimicrobial, biodegradable, and low oral toxicity. Chitosan inhibits the growth of a wide variety of bacteria and fungi showing a broad spectrum of antimicrobial acti
Publicado em: 2010
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33. Avaliação dos constituintes e do potencial mutagênico do material particulado oriundo do beneficiamento artesanal da castanha do caju / Assessment of the components and mutagenic potential of particulate matter from artisanal cashew nut roasting
x Despite the social and economic importance of the processing of cashew nuts to Rio Grande do Norte, the production is still carried out artisanally. To collect the almond nut is necessary to roasting. The smoke generated during the burning of the nut has high concentrations of particulate matter (PM) and the PM produced is inhaled daily by families for a p
Publicado em: 2010
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34. Evaluation of beta-carotene microencapsulated antimutagenic activity in cells of rats treated with antitumor doxorubicin using micronucleus test and comet assay / Avaliação da atividade antimutagênica do beta-caroteno microencapsulado em células de ratos tratados com o antitumoral doxorrubicina empregando os ensaios de micronúcleo e cometa
Colorants are commonly used in the food industry. From natural or synthetic origin, these colorants are used in food production in order to recompense the loss of color during manufacturing and stowage processes, guarantee color uniformity and also attribute color to those colorless ones. Among natural pigments, beta-carotene (BC) has been one of the most ad
Publicado em: 2010
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35. Determination of the antimutagenicity of an aqueous extract of Rhizophora mangle L. (Rhizophoraceae), using in vivo and in vitro test systems
An aqueous extract of Rhizophora mangle L. bark is used as raw material in pottery making in the State of Espirito Santo, Brazil. This extract presents large quantities of tannins, compounds possessing antioxidant properties. Tannin antioxidant activity, as a plant chemical defense mechanism in the process of stabilizing free radicals, has been an incentive
Genetics and Molecular Biology. Publicado em: 18/12/2009
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36. The mutagenic and antimutagenic effects of the traditional phytoestrogen-rich herbs, Pueraria mirifica and Pueraria lobata
Pueraria mirifica is a Thai phytoestrogen-rich herb traditionally used for the treatment of menopausal symptoms. Pueraria lobata is also a phytoestrogen-rich herb traditionally used in Japan, Korea and China for the treatment of hypertension and alcoholism. We evaluated the mutagenic and antimutagenic activity of the two plant extracts using the Ames test pr
Brazilian Journal of Medical and Biological Research. Publicado em: 2009-09