Mouse Ears
Mostrando 1-12 de 18 artigos, teses e dissertações.
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1. Regulação do desenvolvimento e determinação do fruto de tomateiro (Solanum lycopersicum) pela via microRNA156/ SQUAMOSA Promoter-Binding Protein-Like (SPL) / MiR156targeted Squamosa Promoter-binding proteins (SPLs) regulate fruit development and determinacy
Many plants have indeterminate growth and are capable of producing new organs and tissues throughout their life. This capability is partially due to the highly regulated expression of specific genes such as SQUAMOSA Promoter-Binding Protein-Like (SPL) genes. SPLs encode plant-specific transcription factors that play important roles in development, such as ph
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 11/04/2012
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2. Effects of strain and age on ear wound healing and regeneration in mice
Round holes in the ears of MRL mice tend to close with characteristics of regeneration believed to be absent in other mouse strains (e.g., C57BL/6). We evaluated the kinetics and the histopathology of ear wound closure in young (8 weeks old) C57BL/6 and BALB/c mice. We also used middle-aged (40 weeks old) C57BL/6 mice to evaluate the influence of aging on th
Brazilian Journal of Medical and Biological Research. Publicado em: 20/11/2009
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3. A Replication-Incompetent Adenovirus Vector with the Preterminal Protein Gene Deleted Efficiently Transduces Mouse Ears
Adenoviruses offer great potential as gene therapy agents but are limited by the strong inflammatory response that occurs in response to the recombinant virus. Since the degree of inflammation correlates in part with the potential of the viral vector for replication, we constructed a preterminal protein (pTP) deletion mutant adenovirus type 5 vector, Ad5dl30
American Society for Microbiology.
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4. Strain-specific and tissue-specific expression of mouse mast cell secretory granule proteases.
As assessed by RNA blot analyses with gene-specific probes, we report that the perivascular connective tissue mast cells (CTMCs) in the ear and skin of BALB/cJ mice contain abundant levels of the mouse mast cell protease (mMCP) 7 transcript, in addition to those protease transcripts present in their serosal mast cells (SMCs). High levels of the mMCP-7 transc
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5. Supporting Cell Characteristics in Long-deafened Aged Mouse Ears
Significant sensory hair cell loss leads to irreversible hearing and balance deficits in humans and other mammals. Future therapeutic strategies to repair damaged mammalian auditory epithelium may involve inserting stem cells into the damaged epithelium, inducing non-sensory cells remaining in the epithelium to transdifferentiate into replacement hair cells
Springer-Verlag.
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6. Mitotic recombination produces the majority of recessive fibroblast variants in heterozygous mice
Mice heterozygous at Aprt (adenine phosphoribosyltransferase) were used as a model to study in vivo loss of heterozygosity (LOH) in normal fibroblasts. Somatic cell variants that exhibited functional loss of the wild-type Aprt in vivo were recovered as APRT-deficient cell colonies after culturing in selection medium containing 2,6-diaminopurine (DAP), an ade
The National Academy of Sciences.
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7. Expression pattern of the mouse ortholog of the Pendred’s syndrome gene (Pds) suggests a key role for pendrin in the inner ear
Pendred’s syndrome is an autosomal-recessive disorder characterized by deafness and goiter. After our recent identification of the human gene mutated in Pendred’s syndrome (PDS), we sought to investigate in greater detail the expression of the gene and the function of its encoded protein (pendrin). Toward that end, we isolated the corresponding mouse ort
The National Academy of Sciences.
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8. Heterozygosity Mapping of Partially Congenic Lines: Mapping of a Semidominant Neurological Mutation, Wheels (Whl), on Mouse Chromosome 4
We identified a semidominant, chemically induced, mouse mutation with a complex array of abnormal behaviors including bidirectional circling and hyperactivity, abnormal circadian rhythmicity and abnormal responses to light. In this report, we genetically and phenotypically characterized the circling/waltzing component of the abnormal behavior. We mapped the
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9. Genetics of Aldehyde Dehydrogenase Isozymes in the Mouse: Evidence for Multiple Loci and Localization of Ahd-2 on Chromosome 19
Electrophoretic and activity variation of the cytoplasmic isozyme of aldehyde dehydrogenase (designated AHD-B4) was observed among inbred strains and Harwell linkage-testing stocks of Mus musculus. The phenotypes are inherited in a normal Mendelian fashion, with two alleles showing co-dominant expression at a single locus (Ahd-2). The locus was shown to segr
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10. Delayed-type hypersensitivity to Phlebotomus papatasi sand fly bite: An adaptive response induced by the fly?
The saliva of bloodsucking arthropods contains a large array of pharmacologically active compounds that assist hematophagy. Arthropod saliva is also responsible for causing uncomfortable allergic responses in its vertebrate hosts. In this article, we investigate whether the sand fly Phlebotomus papatasi, known to produce a strong delayed-type hypersensitivit
National Academy of Sciences.
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11. Detection of Borrelia burgdorferi in urine of Peromyscus leucopus by inhibition enzyme-linked immunosorbent assay.
An inhibition enzyme-linked immunosorbent assay was developed to detect Borrelia burgdorferi, the etiologic agent of Lyme borreliosis, in urine from white-footed mice (Peromyscus leucopus). Of the 87 urine specimens tested from 87 mice collected in widely separated tick-infested sites in Connecticut, 57 (65.5%) contained detectable concentrations of spiroche
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12. Rapid dissemination by the agent of Lyme disease in hosts that permit fulminating infection.
We determined whether the agent of Lyme disease (Borrelia burgdorferi) disseminates more rapidly following deposition in hosts that permit fulminating infection than in hosts in which infection is relatively benign. Thus, individual infected nymphal deer ticks (Ixodes dammini) were permitted to engorge on the ears of C3H mice, and the site of attachment was