Motif Plasticity
Mostrando 1-7 de 7 artigos, teses e dissertações.
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1. O ensino da polifonia pianística: analisando e construindo relações entre dois pólos de um processo.
Given the concept of education as a construction process, this present paper has as its main objective to investigate if the contents of the designated materials for the introduction on the pianistic polyphony teaching at the Curso de Formação Musical I (FM I) of the Escola de Música e Belas Artes do Paraná (EMBAP), convert into representative tools to e
Publicado em: 2008
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2. Segments of the POU domain influence one another's DNA-binding specificity.
The ubiquitously expressed mammalian POU-domain protein Oct-1 specifically recognizes two classes of cis-acting regulatory elements that bear little sequence similarity, the octamer motif ATGCAAAT and the TAATGARAT motif. The related pituitary-specific POU protein Pit-1 also recognizes these two motifs but, unlike Oct-1, binds preferentially to the TAATGARAT
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3. Alternative Splicing Modulation by a LAMMER Kinase Impinges on Developmental and Transcriptome Expression
Alternative splicing is a major contributor to genome complexity, playing a significant role in various cellular functions, including signal transduction, immunity, and development. The spliceosomal machinery is responsible for the processing of nuclear RNA. Several splicing factors associated with this complex are phosphorylated by kinases that possess a co
American Society of Plant Biologists.
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4. Expression cloning of a human polysialyltransferase that forms the polysialylated neural cell adhesion molecule present in embryonic brain.
Polysialic acid is a developmentally regulated posttranslational modification of the neural cell adhesion molecule (N-CAM). It has been suggested that this large anionic carbohydrate modulates the adhesive property of N-CAM, but the precise function of polysialic acid is not known. Here we describe the isolation and functional expression of a cDNA encoding a
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5. The neuregulin receptor ErbB-4 interacts with PDZ-containing proteins at neuronal synapses
Neuregulins regulate the expression of ligand- and voltage-gated channels in neurons and skeletal muscle by the activation of their cognate tyrosine kinase receptors, ErbB 1–4. The subcellular distribution and mechanisms that regulate the localization of ErbB receptors are unknown. We have found that ErbB receptors are present in brain subcellular fraction
The National Academy of Sciences.
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6. Localization of the protein product of the immediate early growth response gene, Egr-1, in the kidney after ischemia and reperfusion.
Egr-1 is an "immediate early" gene that is induced by growth factors and agents that induce differentiation and encodes a protein with a "zinc-finger" motif. This protein is believed to be involved in transcriptional regulation. Because the fate of the kidney, and hence the organism, after an ischemic insult is dependent upon cellular repair, differentiation
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7. Biochemistry and Comparative Genomics of SxxK Superfamily Acyltransferases Offer a Clue to the Mycobacterial Paradox: Presence of Penicillin-Susceptible Target Proteins versus Lack of Efficiency of Penicillin as Therapeutic Agent
The bacterial acyltransferases of the SxxK superfamily vary enormously in sequence and function, with conservation of particular amino acid groups and all-α and α/β folds. They occur as independent entities (free-standing polypeptides) and as modules linked to other polypeptides (protein fusions). They can be classified into three groups. The group I SxxK
American Society for Microbiology.