Monooxygenase
Mostrando 1-12 de 564 artigos, teses e dissertações.
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1. Evaluation of Reference Genes for Quantitative PCR in Four Tissues from Rabbits with Hypercholesterolaemia
Abstract Rabbit with hypercholesterolaemia is an important model for studying cholesterol metabolism disease. This study aimed to evaluate the expression stability of nine reference genes for quantitative PCR (qPCR) analysis in adrenal gland, liver, spleen, and kidney tissue from rabbits with hypercholesterolaemia. In total, 30 male Harbin Large White (HLW)
Braz. arch. biol. technol.. Publicado em: 20/12/2019
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2. Enzymatic potential of heterotrophic bacteria from a neutral copper mine drainage
Abstract Copper mine drainages are restricted environments that have been overlooked as sources of new biocatalysts for bioremediation and organic syntheses. Therefore, this study aimed to determine the enzymatic activities (esterase, epoxide hydrolase and monooxygenase) of 56 heterotrophic bacteria isolated from a neutral copper mine drainage (Sossego Mine,
Braz. J. Microbiol.. Publicado em: 2016-12
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3. Involvement of miR-30c in resistance to doxorubicin by regulating YWHAZ in breast cancer cells
MicroRNAs (miRNAs) are small RNA molecules that modulate gene expression implicated in cancer, which play crucial roles in diverse biological processes, such as development, differentiation, apoptosis, and proliferation. The aim of this study was to investigate whether miR-30c mediated the resistance of breast cancer cells to the chemotherapeutic agent doxor
Braz J Med Biol Res. Publicado em: 10/01/2014
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4. Transcriptional profiling of genes involved in n-hexadecane compounds assimilation in the hydrocarbon degrading Dietzia cinnamea P4 strain
The petroleum-derived degrading Dietzia cinnamea strain P4 recently had its genome sequenced and annotated. This allowed employing the data on genes that are involved in the degradation of n-alkanes. To examine the physiological behavior of strain P4 in the presence of n-alkanes, the strain was grown under varying conditions of pH and temperature. D. cinname
Braz. J. Microbiol.. Publicado em: 2013
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5. Degradação do tetracloroeteno por consórcios bacterianos em reator horizontal de leito fixo / Degradation of tetrachloroethene by bacterial consortia in horizontal fixed bed reactor
O tetracloroeteno (PCE), um dos principais contaminantes de águas subterrâneas, é uma molécula recalcitrante, com toxicidade elevada. Processos de biorremediação de água ou solo contaminados com PCE são normalmente limitados pela baixa eficiência de microrganismos sabidamente envolvidos em sua degradação. No entanto, a prospecção de novos micror
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 25/11/2011
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6. Cloning, expression and characterization of flavin-containing monooxygenese from Coffea arabica / Clonagem, expressão e caracterização de uma flavina monooxigenase de Coffea arabica
Uma grande quantidade de genes que codificam flavina monooxigenases (Flavin containing monooxygenases - FMOs) é encontrada em genomas vegetais, embora poucas funções biológicas tenham sido relacionadas com esse grupo de enzimas em plantas. Um importante papel desempenhado por FMOs é a conversão de triptamina em N-hidroxil niptamina, reação catalisada
Publicado em: 2009
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7. Genetic characterization of morphologically variant strains of Paracoccidioides brasiliensis
Molecular characterization of Paracoccidioides brasiliensis variant strains that had been preserved under mineral oil for decades was carried out by random amplified polymorphic DNA analysis (RAPD). On P. brasiliensis variants in the transitional phase and strains with typical morphology, RAPD produced reproducible polymorphic amplification products that dif
Memórias do Instituto Oswaldo Cruz. Publicado em: 30/04/2008
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8. Influencia dos polimorfismos T6235C e A4889G, do gene CYP1A1, e dos haplotipos NAT1*3, NAT1*4 e NAT1*10 do gene NAT1, associados com o metabolismo de carcinogenos, na susceptibilidade ao adenocarcinoma colorretal esporadico / Influence of T6235C and A4889G polymorphisms of the CYP1A1 gene, and NAT1*3, NAT1*4 and NAT1*10 haplotypes of the NAT1 gene, associated with the carcinogens metabolism, in the susceptibility of the sporadic colorectal adenocarcinoma
The exposure of the cells of the colon and rectum to carcinogenic substances is associated with the consumption of foods that are source of substrates, such as aromatic amines and polycyclic aromatic hydrocarbons. Enzymes such as cytochrome P450 monooxygenase, encoded by the CYP1A1 gene, and acetyltransferase, encoded by the NAT1 gene, are related to the met
Publicado em: 2008
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9. Multibiorreações e suas aplicações para as sinteses de compostos enantiomericamente puros / Multibioreactions applied to the syntheses of enantiomerically pure compounds
The utilization of enzymes for organic compound transformations is an alternative to classical syntheses. Enzymes are used as biocatalysts for the syntheses in vitro of asymmetric compounds because they are intrinsically chiral and result in high catalytic efficiency. In front of the biodiversity of existing microorganisms in Nature and of the necessity to d
Publicado em: 2006
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10. Transformação do fungo ocratoxigênico Aspergillus westerdijkiae medida por Agrobacterium tumefaciens
Aspergillus westerdijkiae is a potent ochratoxin A producer fequently associated to coffee beans. Ochratoxin A is known to have nephrotoxic effects and carcinogenic potential in animal species. Here we report the first Agrobacterium-mediated transformation of A. westerdijkiae. Conidia were transformed to hygromicin B resistance using AGL-1 strain of Agrobact
Publicado em: 2006
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11. High-throughput screening in enzyme assays for epoxide hydrolases and monooxygenases activity detection using whole cell / Triagem de alto desempenho para detecção de atividade de epoxido-hidrolases e monooxigenases utilizando celulas integras
Biocatalysis is a multidisciplinary area, where new technologies are developing rapidly in order to offer unique options and solutions to different organic chemistry problems, complementing the classical synthetic chemistry. Facing the need imposed by progress in this area, this project aims at the implementation of high-throughput screening (HTS) methodolog
Publicado em: 2006
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12. Biotransformações de cetonas aromáticas e cíclicas promovidas por fungos / Biotransformations of cyclic and aromatic ketones by fungi
In this work, we evaluated the enzymatic potential of different Aspergillus strains, through the biotransformations of two substrates: 2- and 4-methylcyclohexanone (1a e 1b). All the strains employed showed alcohol dehydrogenase and Baeyer-Villiger monooxygenase (CPMO and CHMO) activities. These enzymes can perform ketone biorreduction and oxidation. Using t
Publicado em: 2005