Molecules
Mostrando 1-12 de 16456 artigos, teses e dissertações.
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1. Effects of antidiabetics and exercise therapy on suppressors of cytokine signaling-1, suppressors of cytokine signaling-3, and insulin receptor substrate-1 molecules in diabetes and obesity
SUMMARY OBJECTIVE: Pathological destruction of insulin signaling molecules such as insulin receptor substrate, especially due to the increase in suppressors of cytokine signaling molecules, has been demonstrated in experimental diabetes. The contribution of suppressors of cytokine signaling proteins to the development of insulin resistance and the effects o
Revista da Associação Médica Brasileira. Publicado em: 2023
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2. Bimetallic Au-Pd/α-MoO3 Catalyst with High Oxygen Vacancies for Selective Oxidation of Cinnamyl Alcohol
Supported Au-Pd nanoparticles (NPs) have been extensively studied in alcohol oxidation reactions. However, few studies use reducible metal oxides as support, which can activate oxygen molecules and boost the selectivity of the reaction. In this work, Au-Pd NPs were supported on α-MoO3 and evaluated in the selective oxidation of cinnamyl alcohol without solv
Journal of the Brazilian Chemical Society. Publicado em: 2023
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3. Synthesis of Conjugated Molecules Based on Dithienopyrrole Derivatives and Pyrene as Chemosensor for Mesotrione Detection
The conjugated molecules based on pyrene and dithienopyrrole derivatives including 4-(2-ethylhexyl)-2-(pyren-1-yl)-4H-dithieno[3,2-b:2’,3’-d]pyrrole (EP4HP) and 4-(2-ethylhexyl)-2,6-di(pyren-1-yl)-4H-dithieno[3,2-b:2’,3’-d]pyrrole (EDP4HP) have been successfully synthesized via C-H direct arylation reaction. The structures of these conjugated molecul
Journal of the Brazilian Chemical Society. Publicado em: 2022
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4. RECENT ADVANCES IN CYANATION REACTIONS
Transformations involving structurally complex molecules, natural products and representative molecules are extremely important to obtain key reaction intermediates, in addition to accessing molecules with bioactive properties. The development of cyanation methodologies in those molecules becomes important, because nitriles are versatile and important buildi
Química Nova. Publicado em: 2022
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5. Association between inflammatory molecules, nitric oxide metabolites and leg ulcers in individuals with sickle cell anemia
Abstract Introduction Leg ulcers (LUs) are relatively common in patients with sickle cell anemia (SCA). The role of inflammation and nitric oxide (NO) pathways in the pathophysiology of the LU is not understood. Objective The aim of this study was to verify the association between inflammatory molecules and nitric oxide metabolites (NOx) and the occurrence
Hematology, Transfusion and Cell Therapy. Publicado em: 2022
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6. Seleno- and Telluro-Functionalization of Quinones: Molecules with Relevant Biological Application
Quinones and organochalcogens are classes of compounds with great biological applicability, such as antioxidant, anticancer, anti-Alzheimer, and antidepressant activities, among others. Thus, the combination of these two classes of compounds is important to obtain new hits with biological activities that are additive or synergistic. Several methodologies for
Journal of the Brazilian Chemical Society. Publicado em: 2022
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7. Epicardial Fat Tissue Thickness and Omentin in Patients with Atrial Fibrillation
Abstract Background: Although electrical and structural remodeling has been recognized to be important in the pathophysiology of atrial fibrillation, the mechanisms underlying remodeling process are unknown. There has been increasing interest in the involvement of inflammatory molecules and adipokines released from the epicardial fat tissue in the pathophys
International Journal of Cardiovascular Sciences. Publicado em: 2022
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8. Unveiling the Bacterial Sesquiterpenome of Streptomyces sp. CBMAI 2042 Discloses Cyclases with Versatile Performances
Terpenes are the most abundant class of natural product that exist in nature. They possess a myriad of industrial applications including pharmaceutical, perfumery and flavors, bulk chemicals, and fuel. Intriguingly, until today, the vast majority of characterized terpenoids have been isolated from plants and fungi, and only in recent years bacteria were foun
Journal of the Brazilian Chemical Society. Publicado em: 2022
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9. Avanços recentes na síntese do Remdesivir, Molnupiravir (EIDD-2801) e Tenofovir: moléculas promissoras no tratamento da COVID-19
RECENT ADVANCES IN THE SYNTHESIS OF REMDESIVIR, MOLNUPIRAVIR (EIDD-2801) AND TENOFOVIR: PROMISING MOLECULES IN THE TREATMENT OF COVID-19. The search for new treatments to contain the Covid-19 pandemic has highlighted the importance of nucleoside antivirals, such as Remdesivir, Tenofovir and Molnupiravir. Over the last two years, these molecules have been int
Química Nova. Publicado em: 2022
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10. Zinc tungstate: a review on its application as heterogeneous photocatalyst
Abstract ZnWO4 crystallizes in a monoclinic wolframite-like structure, which has been studied for applications in heterogeneous photocatalysis for degradation, oxidation, and reduction of various contaminants. This type of tungstate has proved to be an efficient photocatalyst under both ultraviolet and visible light irradiation and, when ZnWO4 forms a hetero
Cerâmica. Publicado em: 2022
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11. Molecular signature of immunological mechanism behind impaired endometrial receptivity in polycystic ovarian syndrome
ABSTRACT Objective: Despite the treatment of anovulation, infertility is still one of the main complications in PCOS women during reproductive age, which appears to be mainly due to impaired uterine receptivity. This study investigated the transcriptome profiles of endometrium in PCOS patients and healthy fertile individuals as the control group. Material
Archives of Endocrinology and Metabolism. Publicado em: 2022
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12. A New Synthetic Route and Comprehensive Topological Study of a Benzimidazole Derivative
Benzimidazole and its derivatives are molecules that have diverse biological properties, therefore we synthesized and studied a new benzimidazole to understand their physical/chemical properties. The compound was obtained through a new synthetic route, using graphite oxide, in the absence of solvent, with crystalline packaging supported by C-H…N and C-H…
Journal of the Brazilian Chemical Society. Publicado em: 2022