Molecular Biology Database
Mostrando 1-12 de 73 artigos, teses e dissertações.
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1. System-Pharmacology Dissection of Traditional Chinese herbs SINI Decoction for Treatment of Cardiovascular Diseases
Abstract: Cardiovascular diseases (CVDs) are leading causes of death in the world, owing to noticeable incidence and mortality. Traditional Chinese Medicine (TCM) SINI Decoction (SND) is used to prevent and treat CVDs, which has attracted extensive attention for its moderate and little side effects. However, the involved molecular mechanisms are exceedingly
An. Acad. Bras. Ciênc.. Publicado em: 23/09/2019
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2. A quality model for characterizing and selecting molecular biology databases / Um modelo de qualidade para caracterização e seleção de bancos de dados de biologia molecular
O número de banco de dados de biologia molecular presentes na Web vem aumentando significativamente nos últimos anos. A dificuldade de localizar estes bancos de dados na Web incentivou a criação de uma série de catálogos. Mesmo com estes catálogos, persiste o desafio de selecionar aqueles bancos de dados que possuem maior qualidade. Normalmente, a sel
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2012
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3. Analysis of the expression of genes involved in the maintenance of copper homeostasis in the human pathogen Paracoccidioides brasiliensis / Análise da expressão de genes envolvidos na manutenção da homeostase de cobre no patógeno humano Paracoccidioides brasiliensis
The fungus Paracoccidioides brasiliensis is a human pathogen with a wide distribution in Latin America. The fungus causes paracoccidioidomycosis when mycelia reachs the lungs. The success of the infection depends on the acquisition of essential micronutrients such as copper, which is required as cofactor for a variety of enzymes important in biological in se
Publicado em: 2009
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4. Interaction of the nuclear receptors with its ligands: Structural studies of the thyroid hormone receptor, mineralocorticoid receptor and peroxisome proliferator-activated receptor / Interações dos receptores nucleares com seus ligantes: Estudos estruturais do receptor de hormônio tireoidiano, do receptor de mineralocorticóide e do receptor ativado por proliferadores peroxissomais
Nuclear receptors are a superfamily of hormone-regulated transcriptional factors. This superfamily includes, for example, the receptor for thyroid hormone, estrogen, androgen, gluco and mineralocorticoid. In this work, we used structural biology and bioinformatic tools to study the interactions between some members of the nuclear receptor superfamily and its
Publicado em: 2009
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5. Identification and partial characterization of SEPALLATA genes in coffee arabica / IdentificaÃÃo e caracterizaÃÃo parcial de genes SEPALLATA em cafà arÃbica
Coffee is one of the most important international commodity, produced in more than sixty countries and it is classified as one of the five agricultural exportation most valued in development countries. One of the biggest difficulties in this crop is the heterogeneity of the flowering process, therefore, imbalance on the fruit maturation, which makes the harv
Publicado em: 2009
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6. ObtenÃÃo e CaracterizaÃÃo de calos e plÃntulas a partir de embriÃes zigÃticos imaturos de Coffea arabica L. e anÃlise in silico do Gene Serk / Obtaining and characterization of calluses and plantules starting from immature zygotic embryos of Coffea arabica L. and gene SERK in silico analysis
It was intended in this work be obtained alternatives to the explant to foliate and nodal seeking the micropropagation of you cultivate of coffee plants related to the quality of the drink, like âBourbon Amareloâ and to the productivity as the âRubiâ for the south area of Minas Gerais. A main plant of Bourbon Amarelo was used for obtaining of the fruits
Publicado em: 2008
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7. FMNL1 : caracterização de um novo gene humano relacionado com a familia das forminas
Formins are proteins that are involved in processes such as morphogenesis, embryonic differentiation, cytokinesis, cell polarity and survival. The formins are multidomain proteins that are conserved from plants to fungi and vertebrates. A search of the ORESTES database, generated from the Human Cancer Genome Project, identified 2 ESTs that were similar to th
Publicado em: 2006
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8. Genoma funcional e análise "in silico" na caracterização e no isolamento de genes envolvidos em gliomas humanos / Caracterization and isolation of genes involved in human gliomas by functional genome and in silico anlysis
Gliomas are the most fatal central nervous system tumors and to date, satisfactory results from chemotherapies or surgical interventions are still not available. The ST1 rat glioma cell line is hyper-responsive to treatment with glucocorticoids (GC), undergoing a complete tumoral to normal phenotypic reversion, both in vitro and in vivo. The P7 glioma cell l
Publicado em: 2006
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9. A CONCEPTUAL MODEL FOR MOLECULAR BIOLOGY / UM MODELO CONCEITUAL PARA BIOLOGIA MOLECULAR
Projetos de genômica e biológica molecular estão gerando dados cujos volumes e complexidades jamais foram observados nesta área. Além disso, fontes de dados e de conhecimento são produzidas e utilizadas por grupos de pesquisa os quais utilizam terminologias diferentes (sinônimos, apelido e fórmulas), sintaxes diferentes (estrutura de arquivos e separ
Publicado em: 2005
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10. Predição de promotores de Bacillus subtilis usando técnicas de aprendizado de máquina
One of the most important goals of bioinformatics is the ability to identify genes in uncharacterized DNA sequences on world wide database. Gene expression on prokaryotes initiates when the RNA-polymerase enzyme interacts with DNA regions called promoters. In these regions are located the main regulatory elements of the transcription process. Despite the imp
Publicado em: 2005
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11. Identification and characterization of homeobox genes in Eucalyptus
Homeobox genes encode transcriptional factors, usually involved in molecular control of plant developmental patterns. They can be divided into several classes according to conserved sequences within the homeobox region and the presence of specific additional sequences. Based on these conserved sequences, we developed a search procedure to identify possible h
Genetics and Molecular Biology. Publicado em: 2005
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12. Soroprevalencia e epidemiologia molecular do herpesvirus humano 8 (HHV-8) em populações brasileiras
CHANG et al first identified human Herpesvirus Type 8 (HHV-8) in 1994 from skin biopsies of patients with Acquired Immunodeficiency Syndrome (AIDS) associated Kaposi?s Sarcoma (KS). HHV-8 is an oncovirus from the Herpesviridae family, Gamaherpesvirinae subfamily and Rhadinovirus genus. It is the only one of its genus to infect humans. Its ultra structure rem
Publicado em: 2005