Modified Release
Mostrando 1-12 de 392 artigos, teses e dissertações.
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1. Nerve-sparing robotic-assisted radical prostatectomy: how I do it after 15.000 cases
ABSTRACT Introduction: Over the years, since Binder and Kramer described the first Robotic-assisted Radical Prostatectomy (RARP) in 2000, different Nerve-sparing (NS) techniques have been proposed by several authors (1). However, even with the robotic surgery advantages, functional outcomes following RARP, especially erection recovery, still challenge surge
International braz j urol. Publicado em: 2022
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2. Novel PEG 4000 derivatives and its use in controlled release of drug indomethacin
The insertion of functional groups in polymer compounds may facilitate their interaction with different drugs. PEG polymers are widely used for their low melting point, low toxicity, drug compatibility, and hydrophilicity. They are used as pharmaceutical excipients for the formulation of conventional or modified released drugs and are designed to be upgraded
Quím. Nova. Publicado em: 2020-06
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3. Effect of a novel bioceramic root canal sealer on the angiogenesis-enhancing potential of assorted human odontogenic stem cells compared with principal tricalcium silicate-based cements
Abstract Objective: This study evaluated the angiogenesis-enhancing potential of a tricalcium silicate-based mineral trioxide aggregate (ProRoot MTA), Biodentine, and a novel bioceramic root canal sealer (Well-Root ST) in human dental pulp stem cells (hDPSCs), human periodontal ligament stem cells (hPLSCs), and human tooth germ stem cells (hTGSCs). Methodo
J. Appl. Oral Sci.. Publicado em: 10/01/2020
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4. AVALIAÇÃO DO PERFIL DE LIBERAÇÃO DO FÁRMACO IBUPROFENO EM MEMBRANAS SIMÉTRICAS E ASSIMÉTRICAS DE ACETATO DE CELULOSE: EFEITO DA MORFOLOGIA
Cellulose derivatives still receive special attention in today biomedical applications due to their biocompatibility, ability to form resistant membranes and compatibility with various bioactive agents. In this work, cellulose acetate (CA) was used to prepare membranes with different morphologies aiming to evaluate the release profile of the drug ibuprofen (
Quím. Nova. Publicado em: 21/10/2019
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5. Sutures modified by incorporation of chlorhexidine and cinnamaldehyde: anti-Candida effect, bioavailability and mechanical properties
Resumo Introdução Fios de suturas com antimicrobianos são uma alternativa terapêutica para o controle de infecções orais. Objetivo Incorporar Clorexidina (CHX) e Cinamaldeído (CN) em fios de sutura e avaliar o efeito anti-Candida, liberação de antimicrobianos e as propriedades mecânicas. Material e método Fios de Seda (S) e Poliglactina 910 (P)
Rev. odontol. UNESP. Publicado em: 22/08/2019
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6. Preparation and characterization of novel, mucoadhesive ofloxacin nanoparticles for ocular drug delivery
The efficacy of conventional ocular formulations is limited by poor corneal retention and permeation, resulting in low ocular bioavailability. Mucoadhesive chitosan (CS)/ tripolyphosphatesodium (TPP) and chitosan (CS)/ tripolyphosphatesodium (TPP)-alginate (ALG) nanoparticles were investigated for the prolonged topical ophthalmic delivery of ofloxacin. A mod
Braz. J. Pharm. Sci.. Publicado em: 15/08/2019
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7. Study on influence of polymer and surfactant on in vitro performance of biodegradable aqueous-core nanocapsules of tenofovirdisoproxil fumarate by response surface methodology
The major objective of this study was to investigate the effect of biodegradable polymer type and surfactant concentration on various characteristics viz. particle size, entrapment efficiency and drug release rate constant of aqueous core nanocapsules (ACNs) containing tenofovirdisoproxil fumarate. In this study, the nanocapsules were prepared by modified mu
Braz. J. Pharm. Sci.. Publicado em: 12/08/2019
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8. Development, characterization and stability of microemulsionated formulations of bacaba, Oenocarpus bacaba oil
RESUMO Os avanços no âmbito da nanotecnologia, aliados ao uso de produtos naturais, representam uma área promissora de pesquisa. O Brasil é um país de rica biodiversidade, especialmente na floresta amazônica. Frutos utilizados comumente nas comunidades locais, como a bacaba (Oenocarpus bacaba), são potencialmente interessantes para prospecção de apl
Acta Amaz.. Publicado em: 12/08/2019
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9. SYNTHESIS, CHARACTERIZATION AND in vitro CYTOTOXICITY OF Acacia mearnsii PROANTHOCYANIDIN LOADED PLGA MICROPARTICLES
ABSTRACT One of the highlighted areas in the development of new materials is the generation of micro- and nanoparticles as drug carriers which allow the progress in formulations with the ability to release active agents in a controlled way. The proanthocyanidins (PAC) extracted from the bark of the Black Wattle have stood out for their biological activities.
Braz. J. Chem. Eng.. Publicado em: 15/07/2019
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10. A New Phe-Free Protein Substitute Engineered to Allow a Physiological Absorption of Free Amino Acids for Phenylketonuria
Abstract An innovative technology (Physiomimic Technology) has been applied to amino acids (AAs) formulated for patients with phenylketonuria, with the objective of masking AA taste and odor and prolonging AA release in the gut, allowing a physiological absorption. This technology entails that the AAs are processed with functional additives that are able to
J. inborn errors metab. screen.. Publicado em: 28/02/2019
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11. Fluoride release and uptake in enhanced bioactivity glass ionomer cement (“glass carbomer™”) compared with conventional and resin-modified glass ionomer cements
Abstract Objectives To study the fluoride uptake and release properties of glass carbomer dental cements and compare them with those of conventional and resin-modified glass ionomers. Materials and Methods Three materials were used, as follows: glass carbomer (Glass Fill), conventional glass ionomer (Chemfil Rock) and resin-modified glass ionomer (Fuji II
J. Appl. Oral Sci.. Publicado em: 21/02/2019
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12. Resin-modified glass ionomer containing calcium glycerophosphate: physico-mechanical properties and enamel demineralization
Abstract Sources of calcium and phosphate have been added to dental restorative materials to improve their anticaries effect. Objective This study evaluated the effect of adding calcium glycerophosphate (CaGP) to resin-modified glass ionomer cement (RMGIC) on the physico-mechanical properties, ion release, and enamel demineralization. Material and Methods:
J. Appl. Oral Sci.. Publicado em: 21/02/2019