Modified Release
Mostrando 13-24 de 392 artigos, teses e dissertações.
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13. Investigation on Structural, Morphological and Relaxometric Properties of Lamellar Zrp Modified with Long Chain Amine
In order to search nanofiller for controlling release of drugs lamellar α-zirconium phosphate (α-ZrP) was modified with ether-amine oligomer (E-A). Synthesis and chemical modification followed specific reaction conditions and different EA:ZrP ratios. Infrared spectra showed strong interaction between P-OH and NH2 groups. Thermogravimetric curves showed tha
Mat. Res.. Publicado em: 17/01/2019
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14. Directives and requirements for genetically modified (GM) crop regulation in Argentina
Abstract Regulation of GM crops prior to their commercial release requires research under controlled conditions, either in confined field trials, in greenhouses, and/or in the laboratory. Authorizations in Argentina can be obtained for experimental or confined field trials and “counter-season” production of regulated seed. These trials represent the firs
Crop Breed. Appl. Biotechnol.. Publicado em: 2018-09
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15. Adenanthera pavonina GALACTOMANNAN FOR CONTROLLED DELIVERY OF RUTIN - A PRELIMINARY STUDY
Improving the development of modified release matrix systems strictly depends on selecting an appropriate agent capable of controlling the drug's release. In this study, Adenanthera pavonina galactomannan was investigated as a potential basis for developing a controlled release of rutin. This galactomannan was extracted, purified and characterized by GPC, NM
Quím. Nova. Publicado em: 2018-06
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16. Effects of high fat diet on kidney lipid content and the Na,K-ATPase activity
ABSTRACT It is widely known that high fat diet (HFD) can contribute to the advent of health problems. Recent studies have indicated that obesity imposes a hemodynamic overload to the kidneys. In order to further investigate such injuries, two groups of six Swiss mice each were fed with a controlled AIN93G diet or a high fat (AIN93G modified) diet for eight w
Braz. J. Pharm. Sci.. Publicado em: 14/05/2018
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17. Doxycycline-containing glass ionomer cement for arresting residual caries: an in vitro study and a pilot trial
Abstract In a previous study, we demonstrated that the incorporation of doxycycline hyclate (DOX) into resin-modified glass ionomer cement (RMGIC) inhibited important cariogenic microorganisms, without modifying its biological and mechanical characteristics. In this study, we keep focused on the effect of that experimental material as a potential therapy for
J. Appl. Oral Sci.. Publicado em: 07/05/2018
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18. Are stem nectaries common in Gentianaceae Juss.?
ABSTRACT Extrafloral nectaries (EFNs) are specialized structures that produce and release nectar and are located on leaves, cotyledons and, more seldomly, stems. Peculiar leaf nectaries have been described for thirty-three Neotropical species of Gentianaceae, while stem nectaries have been reported for only nine. The aim of this study was to verify the occur
Acta Bot. Bras.. Publicado em: 13/03/2017
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19. Effect of lectin (ScLL) on fibroblasts stimulated with LPS - an in vitro study
Abstract: The lectin (ScLL) extracted from the Synadenium carinatum plant has been evaluated as an immunomodulator in diseases such as asthma, neosporosis and leishmaniasis. However, it has not yet been evaluated in the oral cavity. This study evaluated the effect of ScLL on viability, proliferation and release of IL-10 in human gingival fibroblasts (HGF) st
Braz. oral res.. Publicado em: 22/12/2016
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20. Neutrophil elastase ameliorates matrix metalloproteinase-9 to promote lipopolysaccharide-induced acute lung injury in mice 1
ABSTRACT PURPOSE: To investigate the regulatory roles of neutrophil elastase (NE) and matrix metalloproteinase-9 (MMP-9) in lipopolysaccharide (LPS)-induced acute lung injury (ALI) in mice. METHODS: To construct LPS-induced ALI mouse models, wild-type C57BL/6 mice were administered 5.0 mg/kg of LPS through endotracheal, and/or 1.0 mg/kg of ONO-5046, and/
Acta Cir. Bras.. Publicado em: 2016-06
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21. Functionalized Multi Walled Carbon Nanotubes as a Carrier for Doxorubicin: Drug Adsorption Study and Statistical Optimization of Drug Loading by Factorial Design Methodology
Multi walled carbon nanotubes (MWNTs) have been identified as an efficient drug carrier. Here a controlled drug delivery system based on modified MWNTs with polyethylene glycol (PEG) was developed (MWNTs-PEG). Then doxorubicin (DOX) as an anticancer drug loaded to nanocarrier. All the parameters affecting the DOX adsorption such as: dose of adsorbent, pH, in
J. Braz. Chem. Soc.. Publicado em: 2016-04
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22. ANÁLISES FÍSICO-QUÍMICAS DE BIOFILMES DE SULFATO DE CONDROITOINA MODIFICADO
Numerous investigations are dedicated to the research and development of new polymer materials destined for innovation in pharmaceutical forms. The application of these technological resources has allowed the commercialization of new therapeutic systems for modified drug release. This investigation aimed to evaluate the association of modified chondroitin su
Quím. Nova. Publicado em: 2015-03
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23. Estimation of Aedes aegypti (Diptera: Culicidae) population size and adult male survival in an urban area in Panama
Traditional mosquito control strategies rely heavily on the use of chemical insecticides. However, concerns about the efficiency of traditional control methods, environmental impact and emerging pesticide resistance have highlighted the necessity for developing innovative tools for mosquito control. Some novel strategies, including release of insects carryin
Mem. Inst. Oswaldo Cruz. Publicado em: 22/08/2014
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24. Inhibition of PKC-dependent extracellular Ca2+ entry contributes to the depression of contractile activity in long-term pressure-overloaded endothelium-denuded rat aortas
We examined the contractile responsiveness of rat thoracic aortas under pressure overload after long-term suprarenal abdominal aortic coarctation (lt-Srac). Endothelium-dependent angiotensin II (ANG II) type 2 receptor (AT2R)-mediated depression of contractions to ANG II has been reported in short-term (1 week) pressure-overloaded rat aortas. Contractility w
Braz J Med Biol Res. Publicado em: 01/08/2014