Mitral Cell
Mostrando 1-12 de 40 artigos, teses e dissertações.
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1. miR-27a protects human mitral valve interstitial cell from TNF-α-induced inflammatory injury via up-regulation of NELL-1
MicroRNAs (miRNAs) have been reported to be associated with heart valve disease, which can be caused by inflammation. This study aimed to investigate the functional impacts of miR-27a on TNF-α-induced inflammatory injury in human mitral valve interstitial cells (hMVICs). hMVICs were subjected to 40 ng/mL TNF-α for 48 h, before which the expressions of miR-
Braz J Med Biol Res. Publicado em: 19/04/2018
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2. Programa de computador para simulação de modelos de neurônios: aplicação à célula mitral do bulbo olfatório / Computer program for neuron models simulation: application to the olfactory bulb mitral cell
O presente trabalho descreve um programa de computador em linguagem Java que reproduz o modelo compartimental reduzido de célula mitral do bulbo olfativo construído por Davison, Feng e Brown (Brain Res. Bull. 51:393-399,2000), como uma simplificação do modelo detalhado de Bhalla e Bower (J. Neurophysiol., 69:1948-1965, 1993). O modelo reduzido considera
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 06/06/2011
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3. A célula periglomerular do bulbo olfatório e seu papel no processamento de odores: um modelo computacional / The Periglomeural Cell of the Olfactry Bulb and its Role in the odor processing: A computational Model.
Os interneurônios do bulbo olfatório são elementos chave para o entendimento do processamento de odores. O papel funcional desses neurônios ainda não é bem compreendido, em especial o papel da célula periglomerular (PG). O presente trabalho consiste em construir um modelo biologicamente plausível da célula PG e investigar os efeitos dessa célula em
Publicado em: 2010
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4. ComputaÃÃo dendrÃtica: uma abordagem de fÃsica estatÃstica
No campo da neurociÃncia computacional, a atividade elÃtrica dos neurÃnios à tradicionalmente modelada por equaÃÃes diferenciais nÃo-lineares acopladas, representando a evoluÃÃo do potencial de membrana e certas variÃveis relacionadas Ãs condutÃncias iÃnicas presentes no sistema. Uma tendÃncia recente consiste na extensÃo desta estratÃgia de
Publicado em: 2007
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5. The distribution of the size and number of mitral cells in the olfactory bulb of the rat.
A computer assisted method was used to measure the distribution of the size and number of cells in the mitral cell layer of ten olfactory bulbs from six Sprague-Dawley rats. The size of mitral cells was found to vary around the coronal but not along the rostrocaudal extent of the bulb. Cells were smaller in the ventral and dorsal aspects of the bulb, and lar
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6. Action potential propagation in mitral cell lateral dendrites is decremental and controls recurrent and lateral inhibition in the mammalian olfactory bulb
In the mammalian main olfactory bulb (MOB), the release of glutamate from lateral dendrites of mitral cells onto the dendrites of granule cells evokes recurrent and lateral inhibition of mitral cell activity. Whole-cell voltage recordings in the mouse MOB in vivo and in vitro show that recurrent and lateral inhibition together control the number, durati
The National Academy of Sciences.
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7. Theta bursts in the olfactory nerve paired with β-adrenoceptor activation induce calcium elevation in mitral cells: A mechanism for odor preference learning in the neonate rat
Odor preference learning in the neonate rat follows pairing of odor input and noradrenergic activation of β-adrenoceptors. Odor learning is hypothesized to be supported by enhanced mitral cell activation. Here a mechanism for enhanced mitral cell signaling is described. Theta bursts in the olfactory nerve (ON) produce long-term potentiation (LTP) of glomeru
Cold Spring Harbor Laboratory Press.
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8. Electrophysiological analysis of mitral cells in the isolated turtle olfactory bulb.
1. An in vitro preparation of the turtle olfactory bulb has been developed. Electrophysiological properties of mitral cells in the isolated bulb have been analysed with intracellular recordings. 2. Mitral cells have been driven antidromically from the lateral olfactory tract, or activated directly by current injection. Intracellular injections of horseradish
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9. Odor-evoked calcium signals in dendrites of rat mitral cells
Mitral cell dendrites do more than passively integrate and convey synaptic potentials to the soma, they release transmitter onto local interneurones to mediate recurrent and lateral inhibition. Several mechanisms may control the level of dendritic intracellular calcium ([Ca2+]) and define timing for dendritic release. Here we investigated in vivo, how o
The National Academy of Sciences.
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10. Mitral stenosis together with a giant cell myocarditis limited to the left atrium
A case is described in which mitral stenosis was associated with a giant cell myocarditis; the latter lesion was, however, localized to the left atrium. A quite high proportion of reported cases of giant cell myocarditis have occurred in association with rheumatic heart disease. The nature of this relationship is discussed and it is concluded that, in such c
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11. TGF-β–dependent pathogenesis of mitral valve prolapse in a mouse model of Marfan syndrome
Mitral valve prolapse (MVP) is a common human phenotype, yet little is known about the pathogenesis of this condition. MVP can occur in the context of genetic syndromes, including Marfan syndrome (MFS), an autosomal-dominant connective tissue disorder caused by mutations in fibrillin-1. Fibrillin-1 contributes to the regulated activation of the cytokine TGF-
American Society for Clinical Investigation.
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12. Mitral Cell β1 and 5-HT2A Receptor Colocalization and cAMP Coregulation: A New Model of Norepinephrine-Induced Learning in the Olfactory Bulb
In the present study we assess a new model for classical conditioning of odor preference learning in rat pups. In preference learning β1-adrenoceptors activated by the locus coeruleus mediate the unconditioned stimulus, whereas olfactory nerve input mediates the conditioned stimulus, odor. Serotonin (5-HT) depletion prevents odor learning, with 5-HT2A/2C ag
Cold Spring Harbor Laboratory Press.