Mir
Mostrando 25-36 de 396 artigos, teses e dissertações.
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25. Prevalence of mental disorders among elderly men: a systematic review and meta-analysis
ABSTRACT BACKGROUND: Elderly men have been characterized as a group vulnerable to suicide, motivated by loneliness, loss of loved ones and feelings of uselessness to family members. OBJECTIVES: To ascertain the prevalence of different mental disorders among elderly men who attempted suicide. DESIGN AND SETTING: Systematic review of observational studie
Sao Paulo Med. J.. Publicado em: 2020-06
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26. Manipulating miR-125a-5p to regulate cancer stem cells phenotype and epithelial to mesenchymal transition in glioblastoma
Resumen El objetivo de este artículo es presentar una investigación etnomatemática y su utilización en la formación de profesores indígenas Kaingang en el área de matemáticas y ciencias naturales. La experiencia trascurre en el marco de las Licenciaturas Interculturales Indígenas de la Universidad Comunitaria de la Región de Chapecó (Unochapecó),
Rev. Assoc. Med. Bras.. Publicado em: 2020-05
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27. miR-125a-5p inhibits cancer stem cells phenotype and epithelial to mesenchymal transition in glioblastoma
RESUMO OBJETIVO O glioblastoma (GBM) é um câncer comum e de alta mortalidade. A transição epitélio-mesênquima (EMT) desempenha um papel vital no desenvolvimento do glioblastoma. O objetivo deste estudo é avaliar o papel do miR-125a-5p no glioblastoma e a tumorigênese de células-troco cancerígenas resistentes a medicamentos quimioterápicos em gli
Rev. Assoc. Med. Bras.. Publicado em: 2020-04
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28. GDF11 ameliorated myocardial ischemia reperfusion injury by antioxidant stress and up-regulating autophagy in STZ-induced type 1 diabetic rats
Abstract Purpose: To investigate whether GDF11 ameliorates myocardial ischemia reperfusion (MIR) injury in diabetic rats and explore the underlying mechanisms. Methods: Diabetic and non-diabetic rats subjected to MIR (30 min of coronary artery occlusion followed by 120 min of reperfusion) with/without GDF11 pretreatment. Cardiac function, myocardial infarc
Acta Cir. Bras.. Publicado em: 13/01/2020
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29. lncRNA OIP5-AS1 targets ROCK1 to promote cell proliferation and inhibit cell apoptosis through a mechanism involving miR-143-3p in cervical cancer
Opa-interacting protein 5 antisense transcript 1 (OIP5-AS1) is one kind of cytoplasmic long non-coding RNA (lncRNA), which has been demonstrated to play a critical function in multiple cancers. However, the detailed mechanism of OIP5-AS1 in the regulation of cervical cancer progression is still obscure. Here, we demonstrated that lncRNA OIP5-AS1 was upregula
Braz J Med Biol Res. Publicado em: 2020-01
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30. IDENTIFICAÇÃO DE ADULTERANTES DE BIODIESEL METÍLICO DE CRAMBE EM MISTURAS COM DIESEL, USANDO FT-MIR E CARTAS DE CONTROLE MULTIVARIADAS BASEADAS NO SINAL ANALÍTICO LÍQUIDO
Adulterants in biodiesel/diesel blends modifies its physical and chemical properties. In this work, Fourier Transform Mid-Infrared spectrometry (FT-MIR) and multivariate control charts based on Net Analyte Signal (NAS) were used to monitor the quality of Crambe methyl biodiesel in relation to the biodiesel content and the presence of adulterants. The calibra
Quím. Nova. Publicado em: 2020-01
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31. Biochanin A attenuates myocardial ischemia/reperfusion injury through the TLR4/NF-κB/NLRP3 signaling pathway
Abstract Purpose: Myocardial ischemia/reperfusion (Ml/R) injury is a leading cause of damage in cardiac tissues, with high rates of mortality and disability. Biochanin A (BCA) is a main constituent of Trifolium pratense L. This study was intended to explore the effect of BCA on Ml/R injury and explore the potential mechanism. Methods: In vivo MI/R injury w
Acta Cir. Bras.. Publicado em: 20/12/2019
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32. Exosomes secreted from miRNA-29b-modified mesenchymal stem cells repaired spinal cord injury in rats
Exosomes, a kind of extracellular vesicle, are promising therapeutic agents for spinal cord injury (SCI). This article aimed to investigate effects of exosomes secreted from miRNA-29b-modified bone marrow mesenchymal stem cells (BMSCs) on SCI. Exosomes were extracted from BMSCs transfected with miRNA-29b or negative control (miR NC). SCI rats were injected i
Braz J Med Biol Res. Publicado em: 05/12/2019
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33. Identification of differentially expressed microRNAs in middle-size ovarian follicles of Meishan and Duroc sows
ABSTRACT This study aimed to investigate the roles of miRNA in the development of ovarian follicles in sows with high ovulation rate. The miRNA expression profiles in middle-size ovarian follicles between Meishan and Duroc sows were characterized by Affymetrix miRNA GeneChip. Seven differentially expressed miRNA were identified. KEGG pathways analyzed the pr
R. Bras. Zootec.. Publicado em: 28/11/2019
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34. Clinical significance and correlation of microRNA-21 expression and the neutrophil-lymphocyte ratio in patients with acute myocardial infarction
OBJECTIVES: To explore the clinical significance and correlation of microRNA-21 (miR-21) and the neutrophil-lymphocyte ratio (NLR) in patients with acute myocardial infarction (AMI). METHODS: The observation group contained 184 patients, while the control group contained 150 patients. The expression of miR-21 in the serum of each group was detected by qRT-
Clinics. Publicado em: 07/11/2019
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35. Identification of the molecular mechanisms associated with acute type A aortic dissection through bioinformatics methods
Aortic dissection is characterized by the redirection of blood flow, which flows through an intimal tear into the aortic media. The purpose of this study was to find potential acute type A aortic dissection (AAAD)-related genes and molecular mechanisms by bioinformatics. The gene expression profiles of GSE52093 were obtained from Gene Expression Omnibus (GEO
Braz J Med Biol Res. Publicado em: 07/11/2019
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36. Upregulation of miR-129-5p increases the sensitivity to Taxol through inhibiting HMGB1-mediated cell autophagy in breast cancer MCF-7 cells
Although Taxol has improved the survival of cancer patients as a first-line chemotherapeutic agent, an increasing number of patients develop resistance to Taxol after prolonged treatment. The potential mechanisms of cancer cell resistance to Taxol are not completely clear. It has been reported that microRNAs (miRNAs) are involved in regulating the sensitivit
Braz J Med Biol Res. Publicado em: 28/10/2019