Mhc Class I
Mostrando 13-24 de 863 artigos, teses e dissertações.
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13. Estudo dos polimorfismos do HLA e microssatélites na infecção pelo HIV-1/AIDS. / Study of HLA and microsatellite markers polymorphisms in the HIV-1 disease.
[INTRODUÇÃO] Fatores genéticos do hospedeiro podem promover resistência à infecção pelo HIV-1 e o retardo no curso da doença. O polimorfismo do HLA é considerado determinante na infecção do HIV-1 e AIDS. Os genes HLA, localizados na região de classe I do MHC, ganham destaque nos estudos de associação como fortes candidatos à patogenia da AIDS.
Publicado em: 2008
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14. Imunolocalização e alterações patológicas induzidas pela infecção por Strongyloides venezuelensis em camundongos geneticamente deficientes em MHC de classe I ou II
In the present study, we investigated the mechanisms involved in the immune response of Major Histocompatibility Complex class I or class II knockout mice (MHC I-/- or MHC II-/-), after S. venezuelensis infection. Wild-type C57BL/6 (WT), MHC II -/- and MHC I -/- mice were individually inoculated with 3.000 larvae (L3) of Strongyloides venezuelensis and sacri
Publicado em: 2007
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15. ImunolocalizaÃÃo e alteraÃÃes patolÃgicas induzidas pela infecÃÃo por Strongyloides venezuelensis em camundongos geneticamente deficientes em MHC de classe I ou II
In the present study, we investigated the mechanisms involved in the immune response of Major Histocompatibility Complex class I or class II knockout mice (MHC I-/- or MHC II-/-), after S. venezuelensis infection. Wild-type C57BL/6 (WT), MHC II -/- and MHC I -/- mice were individually inoculated with 3.000 larvae (L3) of Strongyloides venezuelensis and sacri
Publicado em: 2007
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16. Polymorphism of exon 2-3 of bovine major histocompatibility complex class I BoLa-A gene
The exon 2-3 region of bovine major histocompatibility complex (MHC) class I BoLa-A gene was investigated for polymorphisms in three breeds of cattle originated in the Indian subcontinent namely Sahiwal, Tharparkar, Hariana, as well as crossbred (Bos taurus x Bos indicus) cattle and Jersey, the exotic breed (Bos taurus). The PCR amplified fragment of 714 bp
Genetics and Molecular Biology. Publicado em: 2007
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17. Expressão do MHC classe I e sua Influencia sobre as alterações sinaptologicas em camundongos de diferentes linhagens isogenicas, 1 e 3 semanas após a transecção do nervo ciatico / Expression of MHC class I influences synaptological changes in different isogenic mice strains, 1 and 3 weeks after sciatic nerve transection
o estabelecimento das redes nervosas que compõem o Sistema Nervoso Central (SNC) é um processo imensamente complexo dependente, não somente da formação de novos pontos de comunicação, as sinapses, mas também da eliminação de sinapses supranumerárias ou incorretas durante o desenvolvimento. Recentemente, foi descrito um mecanismo demonstrando que a
Publicado em: 2007
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18. À procura do Ped bovino / Searching for the Ped gene
The aim of the present work was to identify bovine MHC class I genes similar to the murine Ped gene expressing during embryonic development and pregnancy. Bovine in vitro produced embryos and placentas obtained from natural mating or cloning-derived fetuses had their RNA extracted. cDNA was synthesized to isolate fragments showing similarity with the gene de
Publicado em: 2005
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19. Caracterização do polimorfismo dos alelos HLA de classe I e nos microssatelites do fator de necrose tumoral em pacientes brasileiros com psoriase vulgar
Introduction - Psoriasis is a genetic chronic inflammatory skin disorder with genes involved in disease predisposition located within the highly polymorphic Major Histocompatibility Complex (MHC) region on the chromosome 6p21.3. The goal of the present study was to identify, evaluate distribution and determine genetic associations of HLA class I genes and Tu
Publicado em: 2005
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20. PRECONDITIONING OF ORGAN DONORS WITH LOW LEVELS OF CARBON MONOXIDE REDUCES GRAFT IMMUNOGENICITY AND IMPROVES LONGTERM ALLOGRAFT FUNCTION
Background: Chronic rejection remains the major obstacle for successful transplantation, and to date there is no effective treatment. Events occurring prior to organ transplantation such as brain death, harvesting procedure, and ischemia-reperfusion injury lead to unspecific inflammatory damages danger signals - that increase graft immunogenicity and reduce
Publicado em: 2005
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21. Expressão da molecula do MHC classe I pelo tumor de Walker 256 durante sua conversão de variante A (agressiva) em variante AR (regressiva)
Novel tumor cell variants can be obtained by serially passaging tumor cells in different media and/or environments. In vivo environmental selective pressures usually account for this phenomenon, leading to tumor cell changes and/or clonal expansions. Serial intraperitoneal (ip) passages of the Walker 256 (W256) tumor A variant was followed in rats for studyi
Publicado em: 2004
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22. Expressão das Moléculas de Histocompatibilidade de Classe I e II em Células Linfomonocitárias de Pacientes com Diabetes Mellitus do Tipo 1 Recentemente Diagnosticados. / Expression of histocompatibility class I and II molecules on lymphomononuclear cells of patients with type 1 diabetes mellitus newly diagnosed.
Althougth the role of MHC molecules in the susceptibility to DM1 has not been elucidated, the density of MHC molecules on cell surface may influence the outcome of the immune response. In this study, the number of CD3+, CD4+, CD8+, CD19+ and CD14+ cells coexpressing MHC class I and II, and the correlation between the density of MHC molecules and the immunoge
Publicado em: 1999
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23. Human Parainfluenza Virus Type 3 Up-Regulates Major Histocompatibility Complex Class I and II Expression on Respiratory Epithelial Cells: Involvement of a STAT1- and CIITA-Independent Pathway
Human parainfluenza virus type 3 (HPIV3) infection causes severe damage to the lung epithelium, leading to bronchiolitis, pneumonia, and croup in newborns and infants. Cellular immunity that plays a vital role in normal antiviral action appears to be involved, possibly because of inappropriate activation, in the infection-related damage to the lung epitheliu
American Society for Microbiology.
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24. Major histocompatibility complex class I molecule expression is normal on peripheral blood lymphocytes from patients with insulin-dependent diabetes mellitus.
Recent work from one laboratory has shown, in both nonobese diabetic mice and humans, an association between insulin-dependent diabetes mellitus (IDDM) and quantitative difference in MHC class I molecule expression. This reported decrease in MHC class I molecule expression is very controversial in the nonobese diabetic mouse model of IDDM, but to our knowled