Mesenchymal Stromal Cells
Mostrando 1-12 de 60 artigos, teses e dissertações.
-
1. Stem cell therapy as a potential treatment option for psoriasis
Abstract Psoriasis is a chronic inflammatory dermatological disorder characterized by white scales and clearly demarcated erythematous plaques. The prevalence of psoriasis varies from country to country and can occur at any age, implying that ethnicity, environmental factors, and genetic background all play a role in its onset. According to the World Psorias
Anais Brasileiros de Dermatologia. Publicado em: 2022
-
2. Effects of intravenous administration of allogeneic mesenchymal stromal cells, derived from adipose tissue, in five dogs with chronic kidney disease
ABSTRACT Este estudo teve como objetivo avaliar a segurança do tratamento com células estromais mesenquimais alogênicas derivadas do tecido adiposo (aASC) em cães com doença renal crônica (CKD) no momento das infusões e durante o acompanhamento de 120 dias após a última infusão. Cinco cães com CKD receberam três infusões intravenosas de aproxima
Arquivo Brasileiro de Medicina Veterinária e Zootecnia. Publicado em: 2022
-
3. 5-Azacytidine restores interleukin 6-increased production in mesenchymal stromal cells from myelodysplastic patients
ABSTRACT Introduction: Myelodysplastic syndromes (MDS) are a heterogeneous group of clonal hematological diseases. In addition to defects in hematologic progenitor and stem cells, dysfunctions in the bone marrow microenvironment (BMM) participate in the MDS pathogenesis. Furthermore, the immune response is deregulated by the pro-inflammatory response prevai
Hematol., Transfus. Cell Ther.. Publicado em: 2021-03
-
4. Growth hormone in the tumor microenvironment
ABSTRACT Tumor development is a multistep process whereby local mechanisms enable somatic mutations during preneoplastic stages. Once a tumor develops, it becomes a complex organ composed of multiple cell types. Interactions between malignant and non-transformed cells and tissues create a tumor microenvironment (TME) comprising epithelial cancer cells, cance
Arch. Endocrinol. Metab.. Publicado em: 10/01/2020
-
5. TRANSPLANTATION OF ADIPOSE-DERIVED MESENCHYMAL STEM CELLS IN REFRACTORY CROHN’S DISEASE: SYSTEMATIC REVIEW
RESUMO Racional: Há diferentes opções de tratamento para a doença de Crohn, porém, em alguns casos, há a necessidade de outras abordagens terapêuticas, como o uso de células-tronco mesenquimais derivadas do tecido adiposo. Objetivo: Revisar sistematicamente a literatura para determinar as diferentes formas de administração das células-tronco mes
ABCD, arq. bras. cir. dig.. Publicado em: 20/12/2019
-
6. Jejunal stromal tumor and neurofibromatosis
Resumo Os tumores estromais gastrointestinais, embora raros, são as neoplasias mesenquimais primárias mais comuns do trato gastrointestinal e originam-se das células intersticiais de Cajal. Apresentam crescimento lento e manifestam sintomas como sangramento, dor ou desconforto abdominal e presença de massa abdominal. Os órgãos mais acometidos são est�
J. Coloproctol. (Rio J.). Publicado em: 05/12/2019
-
7. Mesenchymal Stromal Cells Modulate PAF-stimulated Equine Alveolar Macrophages
Abstract Platelet-activating factor (PAF) is a potent proinflammatory mediator that is produced in increased amounts in the lungs of asthmatic humans and horses. The present pilot study, shows that mesenchymal stromal cells can modulate alveolar macrophage function in asthma, interfering in the activity of PAF, being another potential pathway for mesenchyma
Braz. arch. biol. technol.. Publicado em: 25/11/2019
-
8. Standardization and quality assessment for clinical grade mesenchymal stem cells from human adipose tissue
Abstract Background Mesenchymal stem cells have immense potential in stem cell-based therapies, however there is a pre-requisite to develop a curative cell dose. Adipose tissue-derived mesenchymal stem cells are promising mainly due to their potential abundance, immunomodulatory effect and remarkable differentiation potential. Nevertheless, senescence may d
Hematol., Transfus. Cell Ther.. Publicado em: 15/04/2019
-
9. Isolation and characterization of mesenchymal stem/stromal cells from Ctenomys minutus
Abstract Mesenchymal stem/stromal cells (MSCs) are multipotent cells distributed in all tissues and characterized by adherence, morphology, immunophenotype and trilineage differentiation potential. The present study aimed to isolate and characterize adherent MSC-like populations from different tissues of Ctenomys minutus, a threatened wildlife rodent popular
Genet. Mol. Biol.. Publicado em: 29/11/2018
-
10. Micromass cultures are effective for differentiation of human amniotic fluid stem cells into chondrocytes
OBJECTIVES: Articular cartilage is vulnerable to injuries and undergoes an irreversible degenerative process. The use of amniotic fluid mesenchymal stromal stem cells for the reconstruction of articular cartilage is a promising therapeutic alternative. The aim of this study was to investigate the chondrogenic potential of amniotic fluid mesenchymal stromal
Clinics. Publicado em: 05/04/2018
-
11. Fetal Cerebrospinal Fluid Promotes Proliferation and Neural Differentiation of Stromal Mesenchymal Stem Cells Derived from Bone Marrow
ABSTRACT Embryonic cerebrospinal fluid (E-CSF) contains many neurotrophic and growth factors, acts as a growth medium for cortical progenitors, and can modulate proliferation and differentiation of neural stem cells. Mesenchymal stem cells (MSCs) are multipotential stem cells that can differentiate into several types of mesenchymal cells as well as nonmesenc
Braz. arch. biol. technol.. Publicado em: 08/01/2018
-
12. Differential profile of CDKN1A and TP53 expressions in bone marrow mesenchymal stromal cells from myeloid neoplasms
Rev. Bras. Hematol. Hemoter.. Publicado em: 2016-12