Memory T Cells
Mostrando 1-12 de 587 artigos, teses e dissertações.
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1. Comparative evaluation of memory T cells in COVID-19 patients and the predictive role of CD4+CD8+ double positive T lymphocytes as a new marker
RESUMO OBJETIVO: A pandemia de COVID-19 tem afetado o mundo todo, constituindo uma ameaça grave para a saúde humana. As células T desempenham um papel crítico na imunidade celular contra infecções virais. Procuramos desvendar a relação entre sub grupos de células T e a severidade da doença. MÉTODOS: Um total de 40 pacientes com COVID-19 foram al
Rev. Assoc. Med. Bras.. Publicado em: 2020-12
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2. Immunosenescence: participation of T lymphocytes and myeloid-derived suppressor cells in aging-related immune response changes
RESUMO O envelhecimento saudável está relacionado, pelo menos em parte, com a função adequada do sistema imunológico. Isso porque já foi relatado que, com o envelhecimento, algumas mudanças desse sistema são observadas, como a diminuição da percentagem e do repertório de células T pela involução tímica, acúmulo de células T de memória por i
Einstein (São Paulo). Publicado em: 02/05/2019
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3. Dendritic cells and their relation to apical peridontitis
Abstract: The purpose of this manuscript was to re-discuss apical periodontitis, apical biofilm, and its possible relationship with dendritic cells (DC). DCs are potent regulators of the immune system and their function is divided into three categories that involve the presentation of antigens: the presentation of antigens and activation of T cells; a not we
Braz. oral res.. Publicado em: 18/10/2018
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4. Immune development in HIV-exposed uninfected children born to HIV-infected women
ABSTRACT Immunological and clinical findings suggestive of some immune dysfunction have been reported among HIV-exposed uninfected (HEU) children and adolescents. Whether these defects are persistent or transitory is still unknown. HEU pediatric population at birth, 12 months, 6-12 years were evaluated in comparison to healthy age-matched HIV-unexposed contr
Rev. Inst. Med. trop. S. Paulo. Publicado em: 01/06/2017
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5. The role of intradermal proliferation of T-cells in the pathogenesis of psoriasis
Abstract: BACKGROUND: Psoriasis is a common immune-mediated chronic inflammatory disease of the skin and joints, affecting 1-3% of the population. It is generally accepted that the pathogenesis of psoriasis involves accumulation of effector T-cells within lymph nodes and their subsequent migration into the skin through the blood system. Here we provide evid
An. Bras. Dermatol.. Publicado em: 2017-02
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6. B cells expressing IL-10 mRNA modulate memory T cells after DNA-Hsp65 immunization
In DNA vaccines, the gene of interest is cloned into a bacterial plasmid that is engineered to induce protein production for long periods in eukaryotic cells. Previous research has shown that the intramuscular immunization of BALB/c mice with a naked plasmid DNA fragment encoding the Mycobacterium leprae 65-kDa heat-shock protein (pcDNA3-Hsp65) induces prote
Braz J Med Biol Res. Publicado em: 18/09/2015
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7. T-cell receptor Vβ repertoire of CD8+ T-lymphocyte subpopulations in cutaneous leishmaniasis patients from the state of Rio de Janeiro, Brazil
In human cutaneous leishmaniasis (CL), the immune response is mainly mediated by T-cells. The role of CD8+ T-lymphocytes, which are related to healing or deleterious functions, in affecting clinical outcome is controversial. The aim of this study was to evaluate T-cell receptor diversity in late-differentiated effector (LDE) and memory CD8+ T-cell subsets in
Mem. Inst. Oswaldo Cruz. Publicado em: 24/06/2015
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8. Involvement of memory T-cells in the pathophysiology of chronic lymphocytic leukemia
The role of T-cells in the pathogenesis of chronic lymphocytic leukemia has recently gained much attention due to the importance of the constant interaction between neoplastic B-cells with microenvironment substratum and T-cells. It is believed that these interactions modulate the clinical course of the disease, mainly through the regulation of the expansion
Rev. Bras. Hematol. Hemoter.. Publicado em: 2014-01
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9. Decreased memory T-cell response and function in human immunodeficiency virus-infected patients with tegumentary leishmaniasis
The effects of human immunodeficiency virus (HIV) on the immune response in patients with cutaneous leishmaniasis have not yet been fully delineated. This study quantified and evaluated the function of memory T-cell subsets in response to soluble Leishmania antigens (SLA) from patients coinfected with HIV and Leishmania with tegumentary leishmaniasis (TL). E
Mem. Inst. Oswaldo Cruz. Publicado em: 02/10/2013
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10. Environmental influences on antibody-enhanced dengue disease outcomes
Because an enriched environment (EE) enhances T-cell activity and T-lymphocytes contribute to immunopathogenesis during heterologous dengue virus (DENV) infections, we hypothesised that an EE increases dengue severity. To compare single serotype (SS) and antibody-enhanced disease (AED) infections regimens, serial intraperitoneal were performed with DENV3 (ge
Mem. Inst. Oswaldo Cruz. Publicado em: 2012-12
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11. Papel de SOCS2 na resposta imune e função cardíaca durante a infecção experimental por Trypanosoma cruzi
Infection with Trypanosoma cruzi induces robust inflammation that limits parasite proliferation but may result in Chagas heart disease. The 5-Lipoxygenase pathway induces suppressor of cytokine signaling(SOCS)2 expression, an important regulator of immune responses. Here, we investigated the role of SOCS2 for the pathogenesis of T. cruzi infection. We invest
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 20/12/2011
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12. Caracterização fenotípica e funcional de linfócitos T de memória de indivíduos infectados pelo HIV reativos a epitopos T CD4+ derivados de sequências do consenso B do HIV-1 / Phenotypic and functional characterization of memory T lymphocytes from HIV infected individuals reactive to CD4-T epitopes derived from sequences of the HIV-1 B consensus
The persistence of functional memory T cell is important to ensure a protective immunity to Human Immunodeficiency Virus (HIV) infection. Memory T cells have been subdivided into central memory (TCM), effector memory (TEM) and highly differentiated effector memory (TEMRA) based on the expression of surface molecules such as CCR7 and CD45RA, and the ability t
Publicado em: 2010