Mechanical Nociceptive Threshold
Mostrando 1-12 de 23 artigos, teses e dissertações.
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1. Morphological and nociceptive effects of mechanical vibration on the sciatic nerve of oophorectomized Wistar rats
Abstract Aim: To evaluate the effects of whole-body vibration in the sciatic nerve of oophorectomized Wistar rats, on nociceptive and morphological parameters, such as fiber, axon, and myelin sheath diameters, G ratio, number of nerve fiber and nuclei of Schwann cells, and percentage of connective tissue. Method: Sixty-four rats were used in the groups sha
Motriz: rev. educ. fis.. Publicado em: 25/04/2019
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2. Potencial Antinocipcetivo Mecânico E Efeitos Sobre A Hiperalgesia Pós-Incisional Do Tramadol Em Equinos / Mechanical antinociceptive potential and effects in the post incisonal iperalgesia of tramadol in horses
O tramadol é um fármaco analgésico com ação em receptores opioides e não opioides, que atua promovendo ativação central dos mecanismos inibitórios da dor. Na última década, houve significativo avanço em pesquisas relacionadas ao seu emprego em equinos. Há indícios de que o fármaco possua efeito analgésico considerável nessa espécie por meca
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 25/03/2011
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3. Potencial Antinocipcetivo Mecânico E Efeitos Sobre A Hiperalgesia Pós-Incisional Do Tramadol Em Equinos / Mechanical antinociceptive potential and effects in the post incisonal iperalgesia of tramadol in horses
O tramadol é um fármaco analgésico com ação em receptores opioides e não opioides, que atua promovendo ativação central dos mecanismos inibitórios da dor. Na última década, houve significativo avanço em pesquisas relacionadas ao seu emprego em equinos. Há indícios de que o fármaco possua efeito analgésico considerável nessa espécie por meca
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 25/03/2011
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4. Investigation of adenosine endogenous increase decurrent of D-Frutose-1,6-difosfato administration, a glycolytic intermediate. / Investigação do aumento endógeno de adenosina decorrente da administração do intermediário glicolítico D-Frutose-1,6-difosfato
D-Fructose-1,6-bisphosphate (F1,6BP), a high-energy glycolytic pathway intermediate, is reported to have a many pharmacologically effect, but its underlying mechanism of action in inflammation is incompletely understood. In this study, the aim was to examine the function of F1,6BP on cytokines and adenosine. Then, the possible F1,6BP anti-inflammatory activi
Publicado em: 2009
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5. Blockade by calcium antagonists of chemical excitation and sensitization of polymodal nociceptors in the cat's cornea.
1. The possibility that a modified Ca2+ channel mediates chemical and thermal excitation of nociceptors was examined in single polymodal nociceptive fibres of the cat's cornea. 2. Ca2+ channel blockers cadmium (2.5 mM) and diltiazem (1 mM), and high external [Ca2+] (40 mM), markedly reduced nociceptive responses to topical acidic solutions (pH 4.5). 3. Decre
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6. Signalling of a step-like intensity change of noxious mechanical stimuli by dorsal horn neurones in the rat spinal cord.
1. Single-unit extracellular recordings were made from thirty-one dorsal horn neurones in the sacral spinal cord of barbiturate-anaesthetized rats. Each neurone was tested with four noxious mechanical pinches applied to its receptive field on the tail. Each pinch lasted 120 s, with a step-like change in intensity after 60 s. In two pinches the step increased
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7. Cutaneous inhibitory receptive fields of withdrawal reflexes in the decerebrate spinal rat.
1. The inhibitory cutaneous input to the withdrawal reflex pathways to single hindlimb muscles was investigated in decerebrate spinal rats (n = 53) using electromyography. 2. Withdrawal reflexes in the peronei, extensor digitorum longus and tibialis anterior muscles of the leg were strongly inhibited by conditioning mechanical, thermal (CO2 laser) and intrac
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8. The NK1 receptor mediates both the hyperalgesia and the resistance to morphine in mice lacking noradrenaline
Noradrenaline (NA), a key neurotransmitter of the endogenous pain inhibitory system, acutely inhibits nociceptive transmission (including that mediated by substance P), potentiates opioid analgesia, and underlies part of the antinociceptive effects of the widely prescribed tricyclic antidepressants. Lesions of noradrenergic neurons, however, result in either
The National Academy of Sciences.
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9. Determining heat and mechanical pain threshold in inflamed skin of human subjects
In a previous article in the Journal of Visualized Experiments we have demonstrated skin microdialysis techniques for the collection of tissue-specific nociceptive and inflammatory biochemicals in humans. In this article we will show pain-testing paradigms that are often used in tandem with microdialysis procedures. Combining pain tests with microdialysis p
MyJove Corporation.
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10. Relationship of substance P to afferent characteristics of dorsal root ganglion neurones in guinea-pig.
1. The relationship between the afferent properties and substance P-like immunoreactivity (SP-LI) of L6 and S1 dorsal root ganglion (DRG) neuronal somata was examined in anaesthetized guinea-pigs. Glass pipette microelectrodes filled with fluorescent dyes were used to make intracellular recordings and to label DRG somata. The dorsal root conduction velocity
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11. Low-threshold mechanoreceptive and nociceptive units with unmyelinated (C) fibres in the human supraorbital nerve.
1. In recordings from the human supraorbital nerve with tungsten microelectrodes, eleven afferent units with unmyelinated (C) axons were identified on the basis of their conduction velocities (0.6-1.4 m/s). 2. Eight units had low mechanical thresholds (less than or equal to 0.23 g) and could be activated up to their maximal firing rates of about 100 impulses
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12. C nociceptor activity in human nerve during painful and non painful skin stimulation.
Percutaneous recordings from more than one hundred single C fibres have been performed in the radial nerve of conscious human subjects. All these fibres belong to the poly-modal C nociceptor group, being excited by mechanical and thermal and also by chemical stimulation. Conduction velocities showed a monophasic distribution with a mean value of 0.86 m/s (SD