Malformations Of Cortical Development
Mostrando 1-11 de 11 artigos, teses e dissertações.
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1. Espectroscopia de fósforo por ressonância magnética em malformações do desenvolvimento cortical
IntroductionMalformations of cortical development (MCD) result from disruptions in the dynamic process of cerebral corticogenesis and are important causes of epilepsy, motor deficits and cognitive impairment.ObjectivesThe aim of this study was to evaluate phospholipids metabolism in vivo in a series of patients with epilepsy and MCD.MethodsThirty-seven patie
Arq. Neuro-Psiquiatr.. Publicado em: 2013-07
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2. Estratégia para investigação molecular de epilepsia com identificação de genes relacionados a formas de polimicrogiria = : Strategy of molecular investigation on epilepsy with the identification of genes related to poymicrogyrias / Strategy of molecular investigation on epilepsy with the identification of genes related to poymicrogyrias
A polimicrogiria (PMG) é uma malformação do córtex cerebral causada por falhas no seu desenvolvimento, caracterizando-se por um número excessivo de pequenos giros e laminação anormal, dando à superfície cortical uma aparência irregular e grosseira. A gravidade de suas manifestações clínicas se relaciona diretamente com a extensão da malformaç�
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/08/2012
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3. O papel dos microRNAs nas displasias corticais focais = : The role of microRNAs in focal cortical dysplasias / The role of microRNAs in focal cortical dysplasias
A displasia cortical focal (DCF) é uma malformação do córtex cerebral humano que ocorre na fase de proliferação e diferenciação neuronal e está frequentemente associada com a refratariedade das crises epilépticas. É designada como um espectro de anormalidades da estrutura laminar do córtex, associada com características citopatológicas que incl
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 04/07/2012
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4. Espectroscopia de fósforo por ressonância magnética em malformações do desenvolvimento cortical / Phosphorus magnetic resonance spectroscopy in malformations of cortical development
INTRODUÇÃO: As malformações do desenvolvimento cortical (MDC) resultam de distúrbios no dinâmico processo de corticogênese cerebral e são importante causa de epilepsia grave, atraso do desenvolvimento, déficits motores e cognitivos. O papel do metabolismo na epilepsia humana tem sido extensamente debatido, e há inúmeras evidências que apontam par
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 26/08/2011
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5. Auditory processing assessment in the perisylvian syndrome / Caracterização dos achados da avaliação do processamento auditivo na Sindrome Perysylviana
Perisylvian syndrome (PS) comprises a variety of clinical manifestations due to lesions on the perisylvian or opercular regions. Bilateral perisylvian polymicrogyria is a malformation of cortical development characterized by excessively small gyri seen around the Sylvian fissure on magnetic resonance imaging. Studies suggest that language and learning impair
Publicado em: 2010
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6. Disturbios do desenvolvimento cortical e epilepsia autossomica dominante com auras auditivas : estudos geneticos e moleculares / Malformations of cortical development and autosomal dominant partial epilepsy with auditory features
Temporal Lobe Epilepsy (TLE) and malformations of cortical development (MCD) are two of the most important causes of epilepsy. Extensive molecular genetic studies have resulted in gene discovery for MCD such as periventricular nodular heterotopia (PNH), lisencephaly/ subcortical band heterotopia spectrum (LIS-SBH), schizencephaly, polymicrogyria and for a su
Publicado em: 2008
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7. Estudos de neuroimagem quantitativa em individuos com anomalias craniofaciais
31 individuals were studied with different cranium-facial anomalies using a previously defined protocol, composed by clinical and cytogenetics evaluation, morphological evaluation (magnetic resonance image [MRI] with multiplanar reformatting [MPR]) and of functional investigation (Electroencephalogram [EEG] and/or single-photon emission computed tomographic
Publicado em: 2005
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8. Estudo de mutações em genes responsaveis por diferentes formas de disturbios do desenvolvimento cortical
Cortical development malformations (CDM) are one of the most important causes of epilepsy and developmental delay. Extensive molecular genetic studies have resulted in gene discovery for CDM such as periventricular nodular heterotopia (PNH), lisencephaly/ subcortical band heterotopia spectrum (LIS/SBH) and schizencephaly. The main goals of this project were
Publicado em: 2003
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9. Reelin' in Genes for Cortical Dysplasia
Malformations of cortical development are a broad family of disorders that are characterized by abnormal cytoarchitecture of the cerebral cortex and a high association with epilepsy. In recent years positional cloning strategies have been implemented to identify several distinct gene mutations that are responsible for developmental brain malformations. The d
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10. A Locus for Bilateral Perisylvian Polymicrogyria Maps to Xq28
Polymicrogyria (PMG) is one of a large group of human cortical malformations that collectively account for a significant percentage of patients with epilepsy, congenital neurological deficits, and intellectual disability. PMG is characterized by an excess of small gyri and abnormal cortical lamination. The most common distribution is bilateral, symmetrical,
The American Society of Human Genetics.
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11. Developmental disruption of serotonin transporter function impairs cerebral responses to whisker stimulation in mice
There is growing evidence that serotonin (5-hydroxtryptamine, 5-HT) has major influences on brain development in mammals. Genetic and pharmacological disruption of 5-HT signaling during early postnatal development in rodents causes neuroanatomical cortical abnormalities, including malformations in the somatosensory cortex. Possible functional consequences of
National Academy of Sciences.