Lipogenesis And Lipolysis
Mostrando 1-12 de 18 artigos, teses e dissertações.
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1. Obesity-associated Pathways of Anthocyanins
Abstract Anthocyanins have a great potential for human health, as a sub-group of phenolic compounds. Interactions of anthocyanin involved in digestion and thus in obesity consist of inhibition of pancreatic lipase, regulation of lipolysis and lipogenesis, activation of an activated protein kinase enzyme, controlling of digestion hormones (leptin, insulin, gh
Food Sci. Technol. Publicado em: 2021-06
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2. Renin-angiotensin system blockers regulate the metabolism of isolated fat cells in vitro
Due to the presence of the renin-angiotensin system (RAS) in tissues and its specific influence on white adipose tissue, fat cells are possible targets of pharmacological RAS blockers commonly used as anti-hypertensive drugs. In the present study, we investigated the effects of different RAS blockers on fat cell metabolism, more specifically on lipolysis, li
Braz J Med Biol Res. Publicado em: 28/07/2016
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3. New concepts in white adipose tissue physiology
Numerous studies address the physiology of adipose tissue (AT). The interest surrounding the physiology of AT is primarily the result of the epidemic outburst of obesity in various contemporary societies. Briefly, the two primary metabolic activities of white AT include lipogenesis and lipolysis. Throughout the last two decades, a new model of AT physiology
Braz J Med Biol Res. Publicado em: 18/02/2014
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4. Effect of ractopamine on lipid metabolism in vivo - a systematic review
The aim of this article was to evaluate the in vivo mechanism of action through which ractopamine reduces the amount of adipose tissue in carcass of animals fed diets supplemented with this drug. Literature search was carried out, using the keywords Ractopamine, lipogenesis, lipolysis, fatty acid and adipose tissue. The scoring system was designed for the ad
Braz. arch. biol. technol.. Publicado em: 2013-02
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5. Repercussões do destreinamento físico sobre o metabolismo e a celularidade do tecido adiposo branco periepididimal de ratos. / Physical detraining repercussions on metabolism and cellularity of white adipose tissue periepididymal in rats.
All adaptations acquired through physical training are reversible during inactivity. Significant reductions in maximal oxygen uptake (VO2Max) are observed within two-four weeks of detraining. Conversely, the consequences of detraining on adipose tissue are poorly known. The objective was to investigate the physical detraining effects on metabolism and cellul
Publicado em: 2010
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6. Caracterização do perfil diário da lipólise e lipogênese no tecido adiposo de ratos adultos e a influência da pinealectomia. / Characterization of the daily profile of lipolysis and lipogenesis in adipose tissue of adult rats and the influence of pinealectomy.
O objetivo do trabalho foi investigar se há ritmicidade dos eventos lipolíticos e lipogênicos no TA peri-epididimal e caracterizar se a pinealectomia interfere nesse processo. O sacrifício dos animais, controles e pinealectomizados, foi realizado de quatro em quatro horas. Em relação a lipogênese observaram-se diferenças significativas entre os horá
Publicado em: 2010
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7. A expressão da proteína de transferência de colesteril éster (CETP) modula a adiposidade e a expressão de genes envolvidos em lipólise e lipogênese / Cholesteryl ester transfer protein (CETP) expression modulates adiposity and expression of genes involved in lipolysis and lipogenesis
A CETP é uma proteína plasmática que promove a transferência de lípides entre lipoproteínas, causando redução de HDL-colesterol e, portanto, aumento do risco de aterosclerose. Neste trabalho, investigamos o efeito da expressão desta proteína sobre a adiposidade e a expressão diferencial de genes em dois modelos animais. Inicialmente, comparamos ca
Publicado em: 2010
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8. The glucose intolerance that is manifested early in the life in rats retards pubertal development and derranges carbohydrate and lipid metabolism. / A intolerância à glicose que se instala precocemente em ratos retarda o desenvolvimento puberal e desregula o metabolismo lipídico e glicídico.
A crescente prevalência de diabetes mellitus (DM) em nível mundial, a sua incidência cada vez maior em crianças e adolescentes e resultados prévios obtidos em nosso laboratório (piora do quadro diabético em ratos na puberdade) nos levaram a investigar o metabolismo de glicose em tecido adiposo branco na puberdade em ratos controle (CO) e intolerantes
Publicado em: 2008
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9. A suplementação crônica com ácido linoléico conjugado promove redução da massa adiposa e compromete a sensibilidade à insulina no tecido adiposo branco periepididimal. / Chronic supplementation with conjugated linoleic acid reduces adipose mass and mpairs insulin sensitivity in periepidydimal white adipose tissue.
O ácido linoléico conjugado (CLA) é um ácido graxo poliinsaturado, encontrado nos produtos da alimentação. Estudos indicam que o CLA possui ações contra câncer, aterogênese e DM 2 e obesidade. O presente trabalho avaliou os efeitos da suplementação crônica com CLA em ratos Wistar machos e teve como objetivo investigar o desenvolvimento corporal
Publicado em: 2008
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10. Efeito do ácido linoléico conjugado trans-10, cis-12 na regulação da lipogênese e expressão gênica em culturas de tecido adiposo de suínos em crescimento / Efect of trans-10, cis-12 conjugated linoleic acid on lipogenesis and gene expression regulation in adipose tissue cultures from growing pigs
O objetivo deste estudo foi avaliar os efeitos do ácido linoléico conjugado (CLA), especificamente do isômero trans-10, cis-12 em culturas de explante de tecido adiposo de suínos, em crescimento.
Publicado em: 2005
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11. Inhibition of insulin-dependent lipogenesis and anti-lipolysis by protein tyrosine kinase inhibitors.
Protein tyrosine kinase (PTK) blockers which competitively inhibit the kinase activity of insulin receptors were synthesized and their properties examined. The best insulin receptor kinase (IRK) inhibitors possess either one hydroxyphenyl ring and two carboxyl groups or two phenyl rings and one carboxyl group. All the inhibitors, except tBoc-tyrosine aminoma
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12. Lipolysis and lipogenesis from glucose in human fat cells of different sizes: Effects of insulin, epinephrine, and theophylline
Lipogenesis from glucose and lipolysis in human omental and subcutaneous fat cells were studied as functions of adipose cell size and number in adult females. Since subcutaneous fat cells were larger than those prepared from the greater omentum, a comparison could be made of the metabolism of different sizes of cells within individual subjects. Rates per cel