Lateral Hypothalamic Area
Mostrando 1-12 de 24 artigos, teses e dissertações.
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1. Mapeamento anátomo-funcional dos sítios neurais envolvidos nas respostas observadas durante exposição ao ambiente contextual de uma derrota social. / Anatomic and functional mapping of the neural sites involved in the observed responses during the exposition of the environment of a social defeat.
We investigated the neural systems involved in the contextual defense to a social defeat. We established a protocol to observe contextual defensive responses in animals previously defeated by an aggressive conspecific: animals were kept ten days living in a apparatus composed by two cages (room and resident cages). On the 11th day animals were exposed to an
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/08/2012
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2. Estradiol-induced hypophagia is associated with the differential mRNA expression of hypothalamic neuropeptides
Estradiol participates in the control of energy homeostasis, as demonstrated by an increase in food intake and in body weight gain after ovariectomy in rats. In the present study, female Wistar rats (200-230 g, N = 5-15 per group), with free access to chow, were individually housed in metabolic cages. We investigated food intake, body weight, plasma leptin l
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-08
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3. Organization of the ventral tegmental area projections to the VTA-nigral complex and to the hypothalamus in the rat and VTA neurons projecting to the accumbens express insulin receptor substrates. / Organização das projeções da área tegmental ventral para o complexo VTA-substância negra e para o hipotálamo no rato e estudo da expressão dos substratos do receptor de insulina em neurônios da VTA que se projetam para o estriado
Numa primeira etapa, estudamos as conexões da VTA para o complexo VTA-substância negra (SN) utilizando a leucoaglutinina do Phaseolus vulgaris (PHA-L). Estas conexões são substanciais, topograficamente organizadas, com destaque para o pólo caudal da VTA que inerva bilateralmente toda a extensão deste complexo. Numa segunda etapa, estudamos as projeçõ
Publicado em: 2010
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4. Melanin-concentrating hormone and orexin A neuropeptidergic systems in the dorsal motor nucleus of the vagus nerve in rat / Sistema neuropeptidergico do hormonio concentrador de melanina e da orexina A no nucleo motor dorsal do nervo vago em rato
Melanin-concentrating hormone (MCH) and orexin-A (OXA) are neuromediators expressed in neurons distributed in the diencephalum, mainly in the lateral hypothalamic area, projecting nerve fibers to several parts of the central nervous system. These neuropeptides exert potent orexigenic activity, increasing feeding and controlling the energetic balance. Consequ
Publicado em: 2009
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5. Temporal evaluation of c-fos expression in amygdaloid and hypothalamic areas following experimental tooth movement in rats / Avaliação temporal da expressão da proteína FOS em áreas amigdalóides e hipotalâmicas após movimentação dentária experimental em ratos
In the accomplishment of the orthodontic treatment, it is described that the pain happens immediately after the application of orthodontic forces and disappears after few days. Regarding the neural pathways involved in the sensorial mediation of the orthodontic movement (OM) few are the studies that approach this theme, and in the last decades solid founds d
Publicado em: 2008
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6. Efeitos da lesão do núcleo septal intermediário sobre a ingestão de água e parâmetros cardiovasculares em ratos induzidas por diferentes protocolos.
The involvement of the septal area in important regulatory mechanisms of water intake and cardiovascular adjustments has been shown by several studies. The aim of this work is to study the involvement of a subdivision of the lateral septal area on dipsogenic and cardiovascular adjustments. The effects of lateral septal intermediate nucleus lesions (LSI) on t
Publicado em: 2006
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7. Reciprocal Hunger-Regulating Circuits Involving Alpha-and Beta-Adrenergic Receptors Located, Respectively, in the Ventromedial and Lateral Hypothalamus*
The injection of adrenergic and adrenolytic drugs directly into the brain through permanently implanted cannulas has yielded results showing that food consumption in the rat is regulated by a hypothalamic alpha-adrenergic „hunger” system. and a hypothalamic beta-adrenergic „satiety” system. The rats' differential responses to alpha-adrenergic and bet
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8. Ventromedial hypothalamic lesions in rats suppress counterregulatory responses to hypoglycemia.
The central nervous system has been implicated in the activation of counterregulatory hormone release during hypoglycemia. However, the precise loci involved are not established. To determine the role of the ventromedial hypoglycemia, we performed hypoglycemic clamp studies in conscious Sprague-Dawley rats with bilateral VMH lesions produced by local iboteni
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9. Evidence for a hypothalamothalamocortical circuit mediating pheromonal influences on eye and head movements.
A method for simultaneous iontophoretic injections of the anterograde tracer Phaseolus vulgaris leukoagglutinin and the retrograde tracer fluorogold was used to characterize in the rat a hypothalamothalamocortical pathway ending in a region thought to regulate attentional mechanisms by way of eye and head movements. The relevant medial hypothalamic nuclei re
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10. The relationship of the locus coeruleus to the amygdala in the cat.
In eight cats a unilateral lesion was produced in the locus coeruleus using either a 20 degree or a 30 degree rostrocaudal parasagittal electrode approach. The animals were killed after a survival period of 10 days. Ascending locus coeruleus projections found in the five animals with the best area destruction went through the dorsal pontine tegmentum into th
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11. Pro-dynorphin peptides are found in the same neurons throughout rat brain: immunocytochemical study.
It is known that the opioid peptide dynorphin A has a broad distribution throughout the neuraxis. Recent biochemical studies have extended the sequence of dynorphin A by 15 amino acids to include another [Leu]enkephalin-containing peptide known as dynorphin B. These sequence data have been validated by the elucidation of the structure of the hypothalamic mRN
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12. Identification of 26RFa, a hypothalamic neuropeptide of the RFamide peptide family with orexigenic activity
A neuropeptide was isolated from a frog brain extract by HPLC purification and characterized by mass spectrometry. This 26-aa neuropeptide, which belongs to the RFamide peptide family, was designated 26RFa, and its primary structure was established as VGTALGSLAEELNGYNRKKGGFSFRF-NH2. Research in databases revealed the presence of sequences homologous to frog
National Academy of Sciences.