Lactones
Mostrando 13-24 de 183 artigos, teses e dissertações.
-
13. Sesquiterpene lactones from Hedyosmum brasiliense induce in vitro relaxation of rat aorta and corpus cavernosum
Abstract Hedyosmum brasiliense Miq., Chloranthaceae, has been used in Southern Brazil as a sedative, anti-inflammatory, and aphrodisiac. In this study, endothelium-intact and endothelium-denuded rat aortic rings and strips of corpus cavernosum were used to investigate the relaxant effects of an hexane fraction of leaves of H. brasiliense and its sesquiterpen
Rev. bras. farmacogn.. Publicado em: 2016-06
-
14. Effects of budlein A on human neutrophils and lymphocytes
ABSTRACT Sesquiterpene lactones (SLs) are the active constituents of a variety of medicinal plants used in traditional medicine for the treatment of inflammatory diseases and other ailments. Objective In this study, we evaluated whether budlein A modulates the activation of innate and adaptive immune cells such as neutrophils and lymphocytes. Material and
J. Appl. Oral Sci.. Publicado em: 2016-06
-
15. Synthesis and Insecticidal Activity of Lactones Derived from Furan-2(5H)-one
Ten 4,7-methanoisobenzofuran-1(3H)-ones were synthesized and their insecticidal activities against the insect pest Diaphania hyalinata were evaluated. The most active substances have been selected from the initial screening to find the dose to kill 50 (LD50) and 90% (LD90) of the melonworm. Time-mortality curves of the three selected formulations at the LD90
J. Braz. Chem. Soc.. Publicado em: 2015-11
-
16. Cytotoxic sesquiterpene lactones from the aerial parts of Inula aucheriana.
Inula aucheriana DC, uma espécie da família Asteraceae, é conhecida pela produção de lactonas sesquiterpênicas que são metabólitos secundários cititóxicos. No presente estudo, as seguintes lactonas sesquiterpênicas foram isoladas de I. aucheriana: inuchinenolida B, 6-desoxichamissonolida (estevina) e 14-acetoxi-1β,5α,7αH-4β-hidroxi-guai-9(10,
An. Acad. Bras. Ciênc.. Publicado em: 08/05/2015
-
17. Anti-inflammatory sesquiterpene lactones from Tithonia diversifolia trigger different effects on human neutrophils
Abstract The tagitinins isolated of Tithonia diversifolia (Hemsl.) A. Gray, Asteraceae, are the most studied sesquiterpene lactones due to their wide spectrum of pharmacologic activities, especially related with nuclear factor-kappa B inhibition. Nevertheless, detailed studies about the mechanism of action of its active compounds are still lacking. Neutrophi
Rev. bras. farmacogn.. Publicado em: 2015-04
-
18. Lack of AHL-based quorum sensing in Pseudomonas fluorescens isolated from milk
Numerous bacteria coordinate gene expression in response to small signalling molecules in many cases known as acylhomoserine lactones (AHLs), which accumulate as a function of cell density in a process known as quorum sensing. This work aimed to determine if phenotypes that are important to define microbial activity in foods such as biofilm formation, swarmi
Braz. J. Microbiol.. Publicado em: 2014-09
-
19. Composition, anti-quorum sensing and antimicrobial activity of essential oils from Lippia alba
Many Gram-negative pathogens have the ability to produce N-acylhomoserine lactones (AHLs) as signal molecules for quorum sensing (QS). This cell-cell communication system allows them to coordinate gene expression and regulate virulence. Strategies to inhibit QS are promising for the control of infectious diseases or antibiotic resistant bacterial pathogens.
Braz. J. Microbiol.. Publicado em: 2014-09
-
20. Natural sesquiterpen lactones as acetylcholinesterase inhibitors
Embasamento teórico e proposta de estudo: A quantidade de pessoas idosas que sofrem da doença de Alzheimer está aumentando a cada ano. Inibidores de colinesterase têm mostrado serem eficazes em amenizar os sintomas da doença, abrindo, então, um campo de pesquisa para estes tratamentos. Produtos de origem vegetal, que possuem uma reputação como agente
An. Acad. Bras. Ciênc.. Publicado em: 14/05/2014
-
21. Methylobacterium-plant interaction genes regulated by plant exudate and quorum sensing molecules
Bacteria from the genus Methylobacterium interact symbiotically (endophytically and epiphytically) with different plant species. These interactions can promote plant growth or induce systemic resistance, increasing plant fitness. The plant colonization is guided by molecular communication between bacteria-bacteria and bacteria-plants, where the bacteria reco
Braz. J. Microbiol.. Publicado em: 2013-12
-
22. Topical anti-inflammatory activity of yacon leaf extracts
Smallanthus sonchifolius (Poepp.) H. Rob. , Asteraceae, known as yacon, is an herb that is traditionally used for the treatment of diabetes in folk medicine. However, recent studies have demonstrated that this plant has other interesting properties such as anti-microbial and anti-inflammatory actions. Thus, the purpose of this study was to evaluate the topic
Rev. bras. farmacogn.. Publicado em: 10/05/2013
-
23. Antiproliferative activity of Eremanthus crotonoides extracts and centratherin demonstrated in brain tumor cell lines
The genus Eremanthus is recognized by the predominance of sesquiterpene lactones from the furanoheliangolide type, a class of substances extensively tested against cancer cell lines. Thus, the species E. crotonoides (DC.) Sch. Bip., Asteraceae, obtained on "restinga" vegetation was evaluated against U251 and U87-MG glioma cell lines using the MTT colorimetri
Rev. bras. farmacogn.. Publicado em: 16/11/2012
-
24. Genus Mikania: chemical composition and phytotherapeutical activity
The genus Mikania ranks high in the list of best-selling natural products in the world. Its main distribution is in South America, but some species are found in Asia, North America and Africa. It is used for treating fever, rheumatism, colds and respiratory diseases, as well as snake bites and scorpion stings, due to its broad spectrum of action. There are a
Rev. bras. farmacogn.. Publicado em: 23/08/2012