Lactones
Mostrando 1-12 de 183 artigos, teses e dissertações.
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1. Isolation and characterization of sesquiterpene lactones from Calea uniflora Less. and their leishmanicidal and trypanocidal activities
Calea uniflora Less., commonly known in Brazil as “erva-de-lagarto” and “arnica-da-praia”, is used in folk medicine to treat internal and external bruises and as anti-inflammatory. However, despite the popular use there is a lack of information in terms of isolation and biological evaluation of its secondary metabolites. Thus, the aims of this study
Quím. Nova. Publicado em: 2021-06
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2. Synthetic Studies toward (−)-Cleistenolide: Highly Stereoselective Synthesis of New γ-Lactone Subunits
This study describes the stereoselective synthesis of two new γ-lactones in 6 and 3 steps and 19 and 32% yield, respectively, directed toward the total synthesis of the natural product (−)-cleistenolide. The starting material was an enantiomerically pure diacetonide diol, derived from d-mannitol with the required stereocenters for (−)-cleistenolide synt
J. Braz. Chem. Soc.. Publicado em: 2021-04
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3. Mango (Mangifera indica) Aroma Discriminate Cultivars and Ripeness Stages
Mango (Mangifera indica) has many nutritional attributes that stimulate its consumption, such as sweetness, balanced acidity and intense fruity aroma. In this study, it was demonstrated that both the variety and ripening stage have a significant impact on the aroma of mango. The volatile compound profile of “Tommy Atkins”, “palmer”, “espada” and
J. Braz. Chem. Soc.. Publicado em: 2020-07
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4. Relationship Between Parameters of Development and Functional Compounds of Yacon Leaves
Abstract Yacon is a tuberous root from the Andean region being increasingly grown across the world due to the low caloric values of their roots and the functional properties of extractions of its leaves. However, there is still a gap in the knowledge of how the plant develops, and if physical and chemical changes are noticed regarding maturity. The subject o
Braz. arch. biol. technol.. Publicado em: 20/12/2019
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5. Bioactive metabolites in of Ginkgo biloba leaves: variations by seasonal, meteorological and soil
Resumo Ginkgo biloba é um fitoterápico tradicional da medicina chinesa que contém vários componentes que contribuem para suas notáveis bioatividades. Variações sazonais, meteorológicos e de plantio do solo sobre os teores fitoquímicos em folhas de G. biloba, devido aos efeitos do crescimento meteorológico e parâmetros do solo, foram investigadas n
Braz. J. Biol.. Publicado em: 02/12/2019
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6. “Arnicas” from Brazil: comparative analysis among ten species
Abstract The “arnicas” found in Brazil are examples of different species of the family Asteraceae used in popular medicine for its attributed anti-inflammatory action. Among the species known and used as “arnica” we selected: Calea uniflora Less., Chaptalia nutans (L.) Polák, Lychnophora ericoides Mart., Lychnophora pinaster Mart., Lychnophora salic
Rev. bras. farmacogn.. Publicado em: 17/10/2019
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7. Chemical Constituents, Antiproliferative and Antioxidant Activities of Vernonanthura nudiflora (Less.) H. Rob. Aerial Parts
Sesquiterpene lactones are an important class of secondary metabolites frequently isolated from Vernonanthura genus that present a variety of biological properties, including antiproliferative activity. Due to the limitation of pharmacological studies on Vernonanthura nudiflora, the aim of this work was to investigate their antioxidant potential and antiprol
J. Braz. Chem. Soc.. Publicado em: 12/08/2019
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8. Oxone®-Mediated Direct α-Hydroxylation of β-Dicarbonyl Compounds: Racemic Synthesis of Harzialactone A
An environmentally benign method is described for the α-hydroxylation of malonates and cyclic analogues in aqueous medium at room temperature under mild conditions, based on the in situ generation of dimethyldioxirane through the combination of acetone and Oxone®. This procedure was found to be substrate-dependent and was successfully performed to provide
J. Braz. Chem. Soc.. Publicado em: 12/08/2019
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9. In vivo anti-hyperuricemic activity of sesquiterpene lactones from Lychnophora species
ABSTRACT Hyperuricemia is the main cause of gout, an inflammation induced by uric acid deposition in joints. Drugs available present side effects, so there is a need for new treatment alternatives. Lychnophora species are used in folk medicine to treat inflammation, rheumatism and muscle pain. Goyazensolide (10 mg/kg), eremantholide C (25 mg/kg) and lychnoph
Rev. bras. farmacogn.. Publicado em: 27/05/2019
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10. Anthelmintic resistance of injectable macrocyclic lactones in cattle: A systematic review and meta-analysis
Resumo O objetivo deste trabalho foi identificar, avaliar criticamente e resumir os dados disponíveis da literatura primária sobre resistência anti-helmíntica a lactonas macrocíclicas injetáveis em bovinos. Uma meta-análise foi realizada para estimar o “Odds Ratio” e Intervalos de Confiança (95%). Dos 1504 resumos selecionados para elegibilidade
Rev. Bras. Parasitol. Vet.. Publicado em: 11/03/2019
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11. Effect of γ-lactones and γ-lactams compounds on Streptococcus mutans biofilms
Abstract Considering oral diseases, antibiofilm compounds can decrease the accumulation of pathogenic species such as Streptococcus mutans at micro-areas of teeth, dental restorations or implant-supported prostheses. Objective To assess the effect of thirteen different novel lactam-based compounds on the inhibition of S. mutans biofilm formation. Material
J. Appl. Oral Sci.. Publicado em: 22/02/2018
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12. Milk quality parameters associated with the occurrence of veterinary drug residues in bulk tank milk
ABSTRACT Veterinary drug residues in bulk tank milk are important to all sectors of the dairy chain because they are one of the major factors which determine the safety of the final product. This study attempted to identify milk quality parameters that are associated with the occurrence of veterinary drug residues using multivariate principal component analy
Sci. agric. (Piracicaba, Braz.). Publicado em: 2017-06