L Asparagine
Mostrando 1-12 de 285 artigos, teses e dissertações.
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1. Asparaginase: an old drug with new questions
ABSTRACT The long-term outcome of acute lymphoblastic leukemia has improved dramatically due to the development of more effective treatment strategies. L-asparaginase (ASNase) is one of the main drugs used and causes death of leukemic cells by systematically depleting the non-essential amino acid asparagine. Three main types of ASNase have been used so far:
Hematol., Transfus. Cell Ther.. Publicado em: 2020-09
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2. PEG-asparaginase and native Escherichia coli L-asparaginase in acute lymphoblastic leukemia in children and adolescents: a systematic review
Abstract Introduction Acute lymphoblastic leukemia (ALL) is the cancer with the highest incidence in childhood and adolescence, and pharmacotherapy is the primary form of treatment. Objective and methods A systematic review of the efficacy and safety of polyethylene glycol (PEG)-asparaginase in acute lymphoblastic leukemia therapy in children and adolescen
Hematol., Transfus. Cell Ther.. Publicado em: 2020-03
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3. An Appraisal on the Source-to-Sink Relationship in Plants: an Application of Desorption Electrospray Ionization Mass Spectrometry Imaging
Amino acids/ureides and carbohydrates are the main nutrients for the plants growth. These metabolites are continuously translocated through the plant organism via well-known transportation mechanisms. The well-established source-to-sink relationship involves the transfer of these nutrients from mature (source) to young (sink) leaves. Desorption electrospray
J. Braz. Chem. Soc.. Publicado em: 2018-01
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4. Current applications and different approaches for microbial L-asparaginase production
ABSTRACT L-asparaginase (EC 3.5.1.1) is an enzyme that catalysis mainly the asparagine hydrolysis in L-aspartic acid and ammonium. This enzyme is presented in different organisms, such as microorganisms, vegetal, and some animals, including certain rodent's serum, but not unveiled in humans. It can be used as important chemotherapeutic agent for the treatmen
Braz. J. Microbiol.. Publicado em: 2016-12
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5. Luminescent Terbium Doped Aluminate Particles: Properties and Surface Modification with Asparagine
New luminescent organic-inorganic hybrid particles based on Tb-doped aluminates and asparagine (Asn) surface modifiers were investigated. The Tb3+ doped inorganic core was obtained by spray pyrolysis, at 200 ºC γ-AlOOH (BOE:Tbx%) or at 700 ºC γ-Al2O3 (γTA:Tbx%). The reaction of Asn with boehmite in water disaggregated the sub-micronic boehmite particles
J. Braz. Chem. Soc.. Publicado em: 2015-12
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6. Kinetic properties of Streptomyces canarius L- Glutaminase and its anticancer efficiency
Abstract L-glutaminase was produced by Streptomyces canarius FR (KC460654) with an apparent molecular mass of 44 kDa. It has 17.9 purification fold with a final specific activity 132.2 U/mg proteins and 28% yield recovery. The purified L-glutaminase showed a maximal activity against L-glutamine when incubated at pH 8.0 at 40 °C for 30 min. It maintained its
Braz. J. Microbiol.. Publicado em: 09/10/2015
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7. Mass spore production and inoculation of Calonectria pteridis on Eucalyptus spp. under different environmental conditions
Calonectria pteridis is one of the most important causal agents of Calonectria leaf blight (CLB) of Eucalyptus spp. in Brazil, which is a limiting factor for growth of Eucalyptus plantations. In this study we developed standard procedures for in vitro mass spore production and inoculation of C. pteridis for screening plant species and clones for resistance t
Trop. plant pathol.. Publicado em: 2013-10
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8. Fox grape cv. Bordô (Vitis labrusca L.) and grapevine cv. Chardonnay (Vitis vinifera L.) cultivated in vitro under different carbohydrates, amino acids and 6-Benzylaminopurine levels
The aim of this work was to study the influence of sucrose and glucose, amino acids and BAP (6-Benzylaminopurine) levels on in vitro shoot regeneration of fox grape cv. Bordô and grapevine cv. Chardonnay. The nodal segments from micropropagated material were used as explants and half-strength MS medium as the basal medium. Sucrose and glucose at 15, 30 and
Braz. arch. biol. technol.. Publicado em: 2013-04
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9. GROWTH AND CHARACTERIZATION OF OPTICAL CRYSTALS AND PURE L-ASPARAGINE L-ASPARAGINE RADIATED. / CRESCIMENTO E CARACTERIZAÇÃO ÓPTICA DE CRISTAIS DE L-ASPARAGINA PURA E L-ASPARAGINA IRRADIADA.
Neste trabalho apresentamos os resultados do crescimento de cristais de L-Asparagina●H2O e do estudo de suas propriedades ópticas, lineares e não lineares, do cristal como é crescido e após ser submetido a altas doses de raios-X. Os cristais foram crescidos em solução aquosa pelo método de evaporação lenta do solvente. Foram realizadas medidas
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/02/2012
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10. Caracterização e expressão do gene SERK durante a indução de embriogênese somática em soja / Characterization and expression of SERK gene during induction of somatic embryogenesis in soybean
Somatic embryogenesis is a useful tool for plant propagation and a suitable model system for deciphering early events during embryo development. Molecular and genetic studies focused in plant development have reported the involvement of SERK (Somatic Embryogenesis Receptor Kinase) gene in the acquisition of embryogenic competence. In order to increase the ef
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 20/09/2010
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11. Production, purification and characterization of L-asparaginase from Streptomyces gulbargensis
L-asparaginase is an anti-neoplastic agent used in the lymphoblastic leukaemia chemotherapy. In the present study a novel strain, Streptomyces gulbargensis was explored for the production of extra-cellular L-asparaginase using groundnut cake extract. The optimum pH, temperature, inoculum size and agitation speed for enzyme production were pH 8.5, 40ºC, 1x10
Brazilian Journal of Microbiology. Publicado em: 2010-03
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12. The role of nitrate reductase and asparagine synthetase in soybean (Glycine max L.) under nitrogen stress / Papel da redutase do nitrato e da asparagina sintetase em plantas de soja (Glycine max L.) sob condições de estresse de nitrogenio
The root system of soybean (Glycine max L.) is an important site for the assimilation of nitrogen, whether by nitrate assimilation in the roots, or by symbiotic nitrogen fixation in the nodules. The main products of inorganic nitrogen assimilation, the amino acids asparagine and glutamine and the ureides allantoin and allantoic acid, are used in the transpor
Publicado em: 2007