Intercellular Junctions
Mostrando 1-12 de 185 artigos, teses e dissertações.
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1. Effect of magnesium ion on human osteoblast activity
Magnesium, a promising biodegradable metal, has been reported in several studies to increase bone formation. Although there is some information regarding the concentrations of magnesium ions that affect bone remodeling at a cellular level, little is known about the effect of magnesium ions on cell gap junctions. Therefore, this study aimed to systematically
Braz J Med Biol Res. Publicado em: 04/07/2016
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2. Cytotoxic factor secreted by Escherichia coli associated with sepsis facilitates transcytosis through human umbilical vein endothelial cell monolayers
Abstract Culture supernatant of sepsis-associated Escherichia coli (SEPEC) isolated from patients with sepsis caused loss of intercellular junctions and elongation of human umbilical vein endothelial cells (HUVEC). The cytotoxic factor was purified from culture supernatant of SEPEC 15 (serogroup O153) by liquid chromatography process. PAGE (polyacrylamide ge
Braz J Infect Dis. Publicado em: 2016-06
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3. Structural interaction between GFP-labeled diazotrophic endophytic bacterium Herbaspirillum seropedicae RAM10 and pineapple plantlets 'Vitória'
The events involved in the structural interaction between the diazotrophic endophytic bacterium Herbaspirillum seropedicae, strain RAM10, labeled with green fluorescent protein, and pineapple plantlets 'Vitória' were evaluated by means of bright-field and fluorescence microscopy, combined with scanning electron microscopy for 28 days after inoculation. Afte
Brazilian Journal of Microbiology. Publicado em: 2011-03
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4. Modelagem da Microestrutura de Tecidos Cardíacos
A few decades ago the cardiac tissue was believed to be an uniformly connected continumm. Currently, it is known that the cardiac cells are connected to each other via special protein channels called gap junctions, through which the ionic current flows between neighboring cells. The cardiac cells are arranged in distinct layers of muscle fibers surrounded by
Publicado em: 2011
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5. Tumor necrosis factor alpha increases epithelial barrier permeability by disrupting tight junctions in Caco-2 cells
The objectives of this study were to determine the effect of tumor necrosis factor alpha (TNF-α) on intestinal epithelial cell permeability and the expression of tight junction proteins. Caco-2 cells were plated onto Transwell® microporous filters and treated with TNF-α (10 or 100 ng/mL) for 0, 4, 8, 16, or 24 h. The transepithelial electrical resistance
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-04
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6. Expressão e distribuição celular de proteínas associadas às junções intercelulares no pâncreas endócrino durante o desenvolvimento animal e na diabetes tipo 2 / Cellular expression and distribution of intercellular junction proteins in rodent endocrine pancreas during animal development and type 2 diabetes
As junções intercelulares são especializações da membrana plasmática através das quais células dentro de um tecido podem interagir e aderirem-se umas às outras. Nas ilhotas pancreáticas, as diferentes células endócrinas se interconectam por meio das junções de oclusão, comunicante, aderente e desmossomos. Tais contatos intercelulares parecem s
Publicado em: 2010
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7. Evaluation of connexin 43 expression in the miocardium in health dogs submited or not to a cardiopulmonary baypass / Avaliação da expressão da conexina 43 no miocárdio de cães indenes submetidos ou não à técnica de circulação extracorpórea
Cardiopulmonary bypass (CPB) replaces the heart and lung function during the main period of cardiac surgery, and it allows the access of the surgeon inside the organ for a long time, ensuring tissue oxygenation and the elimination of end products. However, this procedure isn´t used as a routine in veterinary medicine because of the high costs, and besides i
Publicado em: 2009
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8. Papel da comunicação intercelular midiada pelas junções comunicantes no mecanismo de secreção de insulina em modelos in vivo de maturação e disfunção do pancreas endocrino / Intercellular communication mediated by gap junction in in vivo models of pancreatic B-cell maturation and dysfunction
O objetivo central dessa tese foi estudar o papel das junções comunicantes (GJs) no processo de maturação da célula B e na patogênese da diabetes tipo 2. Para isso, foram utilizados dois modelos animais. No modelo in vivo de maturação da célula B e do processo secretório de insulina foram empregados ratos em vários estágios do desenvolvimento (fe
Publicado em: 2009
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9. Remodeling of dystrophin-glycoprotein complex, intercalated disk proteins, and contractile proteins in the hearts of mice subjected to sepsis induced by cecal ligation and puncture. / Remodelamento do complexo de glicoproteínas associadas à distrofina, do disco intercalar e das proteínas contráteis no coração de camundongos submetidos à sépsis induzida por ligação e perfuração do ceco
Sepsis and septic shock represent a complex syndrome of systemic inflammatory response, with multiple physiological and immunological abnormalities, commonly caused by bacterial infection. The most important consequence of the response is the involvement of many organs and tissues. Cardiac dysfunction, caused by impairment in myocardial contractility, has be
Publicado em: 2008
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10. Emissões otoacusticas evocadas por estímulo trasiente em recém-nascidas homozigotos normais e heterozigotos para a mutação 35delg no gene da conexina / Transient Evoked otoacoustic emissions in carriers and non-carriers 35delG neonates
ABSTRACT The many areas in public health are becoming more and more united, aiming to provide better quality of life to the patients. For this reason, Audiology and Genetic are working closely, due to research which relates genetic hearing loss to hearing evaluation tests. Mutations in gene GJB2, which encodes conexin protein 26 represent the main cause of g
Publicado em: 2006
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11. Avaliação do papel da conexina 43 na angiogênese, experimentalmente induzida em córnea de camundongos / Evaluation the role of connexin 43 during angiogenesis, experimentally induced in mice córnea
The GAP junctions are intercellular streams responsible for the communication between close cells, which allow small molecules and ions to pass through them maintaining the cellular homeostasis. The GAP junction is formed of six proteins, the connexin. In the endothelial cell, there are the connexin 37, 40 and 43. In this study, we stimulated the angiogenesi
Publicado em: 2005
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12. Regulation of intercellular coupling in acute and chronic heart disease
Effective pump function of the heart depends on the precise control of spatial and temporal patterns of electrical activation. Accordingly, the distribution and function of gap junction channels are important determinants of the conduction properties of myocardium and undoubtedly play other roles in intercellular communication crucial to normal cardiac funct
Brazilian Journal of Medical and Biological Research. Publicado em: 2000-04