Insulin Treatment
Mostrando 1-12 de 947 artigos, teses e dissertações.
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1. Deve-se retirar a sulfonilureia quando for iniciada a insulina em pacientes com diabetes tipo 2 usando metformina e sulfonilureia em doses máximas e sem controle glicêmico adequado?
Não é necessário retirar a sulfonilureia ao iniciar insulina NPH em pacientes com diabetes tipo 2. A manutenção do uso da sulfonilureia durante o início do tratamento com insulina NPH (insulina basal) está associada ao uso de doses 30% menores de insulina, menor risco de hipoglicemias e menor ganho de peso.
Deve-se suspender a sulfonilureia e
Núcleo de Telessaúde Rio Grande do Sul. Publicado em: 12/06/2023
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2. Deve-se suspender o uso de metformina em pacientes diabéticas que engravidam?
O uso da metformina é seguro na gestação, inclusive no primeiro trimestre e pode ser mantido em pacientes diabéticas que engravidam.
A forma de uso é semelhante ao período fora da gestação, assim como a dose. Deve ser considerada como primeira opção em casos de hiperglicemia leve não totalmente controladas com a dieta. Em pacientes com hi
Núcleo de Telessaúde Rio Grande do Sul. Publicado em: 12/06/2023
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3. Effects of antidiabetics and exercise therapy on suppressors of cytokine signaling-1, suppressors of cytokine signaling-3, and insulin receptor substrate-1 molecules in diabetes and obesity
SUMMARY OBJECTIVE: Pathological destruction of insulin signaling molecules such as insulin receptor substrate, especially due to the increase in suppressors of cytokine signaling molecules, has been demonstrated in experimental diabetes. The contribution of suppressors of cytokine signaling proteins to the development of insulin resistance and the effects o
Revista da Associação Médica Brasileira. Publicado em: 2023
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4. The role of intermittent continuous glucose monitoring in a successful outpatient transition from insulin to glibenclamide in a patient with transient neonatal diabetes
SUMMARY Neonatal diabetes mellitus (NDM) is a monogenic form of diabetes occurring mainly in the first 6 months of life. Approximately 30% of transient NDM (TNDM) cases will have an activating mutation in the KATP channel genes ABCC8 and KCNJ11. The majority of the patients with KCNJ11 mutations who are receiving insulin treatment can be transferred to treat
Archives of Endocrinology and Metabolism. Publicado em: 2022
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5. Mediators of energy homeostasis in hyperthyroidism
ABSTRACT Objective: The aim of this study was to assess the effect of hyperthyroidism and its treatment on body weight and composition, insulin resistance, and mediators of appetite and energy homeostasis, namely ghrelin, leptin, adiponectin, and fibroblast growth factor 21 (FGF21). Subjects and methods: Thirty-five adult patients (27 female and 8 male, ag
Archives of Endocrinology and Metabolism. Publicado em: 2022
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6. InsulinAPP application protocol for the inpatient management of type 2 diabetes on a hospitalist-managed ward: a retrospective study
ABSTRACT Objective: We assessed metrics related to inpatient glycemic control using InsulinAPP, an application available for free in Brazil, on the hospitalist-managed ward of our hospital. Subjects and methods: We performed a retrospective study of patients with type 2 diabetes (T2D) admitted from November 2018 to October 2019. InsulinAPP recommends NPH a
Archives of Endocrinology and Metabolism. Publicado em: 2022
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7. Insulin resistance by the triglyceride-glucose index in a rural Brazilian population
ABSTRACT Objective: The aim of this study was to estimate the prevalence of insulin resistance (IR) in a rural population in Brazil, to verify its association with sociodemographic, labor, lifestyle, and health factors. Subjects and methods: This is a cross-sectional study with 790 farmers in the state of Espírito Santo/Brazil. Triglyceride-glucose (TyG)
Archives of Endocrinology and Metabolism. Publicado em: 2022
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8. The effects of macronutrients composition on hormones and substrates during a meal tolerance test in drug-naive and sitagliptin-treated individuals with type 2 diabetes: a randomized crossover study
ABSTRACT Objectives: To evaluate the effect of sitagliptin treatment in early type 2 diabetes mellitus (T2DM) and the impact of different macronutrient compositions on hormones and substrates during meal tolerance tests (MTT). Materials and methods: Half of the drug-naive patients with T2DM were randomly assigned for treatment with 100 mg of sitagliptin, q
Archives of Endocrinology and Metabolism. Publicado em: 2022
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9. Diabetes and bone
Abstract Globally, one in 11 adults has diabetes mellitus of which 90% have type 2 diabetes. The numbers for osteoporosis are no less staggering: 1 in 3 women has a fracture after menopause, and the same is true for 1 in 5 men after the age of 50 years. Aging is associated with several physiological changes that cause insulin resistance and impaired insulin
Archives of Endocrinology and Metabolism. Publicado em: 2022
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10. Hyperglycemia in hospitalized patients of a tertiary care hospital: prevalence and treatment in two cross-sectional evaluations (2011-2020)
ABSTRACT Objective: A study at Centro Hospitalar Universitário do Porto in 2011 revealed suboptimal control of inpatient hyperglycemia and a similar one was carried out in 2020. This study compares the results of 2011 and 2020 regarding prevalence of hyperglycemia, metabolic control, treatment and glycemic profile by infection/non-infection diagnosis. Sub
Archives of Endocrinology and Metabolism. Publicado em: 2022
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11. Pediatric androgenetic alopecia: a retrospective review of clinical characteristics, hormonal assays and metabolic syndrome risk factors in 23 patients
Abstract Background Androgenetic alopecia in the pediatric population is rarely discussed in the literature. Although the prevalence of the metabolic syndrome is increased in patients with early-onset androgenetic alopecia, the presence of metabolic syndrome risk factors in pediatric androgenetic alopecia is unknown. Objective To evaluate the demographics,
Anais Brasileiros de Dermatologia. Publicado em: 2022
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12. Anti-Hyperglycemic Activities, Molecular Docking and Structure-Activity Relationships (SARs) Studies of Endiandric Acids and Kingianins from Endiandra kingiana
Diabetes has become a severe chronic disease worldwide with patients significantly increasing daily. Due to the side effects of insulin and oral hypoglycaemic agents employed in diabetes treatment, scientists are working hard to develop alternative approaches from natural plants that inhibit α-amylase and α-glucosidase. Consequently, by performing a phytoc
Journal of the Brazilian Chemical Society. Publicado em: 2022