Imidazolidines
Mostrando 1-4 de 4 artigos, teses e dissertações.
-
1. Immunological studies and in vitro schistosomicide action of new imidazolidine derivatives
Schistosomiasis is a major public health problem with 207 million people infected and more than 779 million at risk. The drug of choice for treating schistosomiasis is praziquantel (PZQ); however, it is inefficient against immature forms of schistosomes. The aim of this study was to test new imidazolidine derivatives LPSF/PT09 and LPSF/PT10 against adult Sch
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2011
-
2. Efeito do tratamento com novos derivados imidazolidÃnicos e praziquantel sobre os lipÃdios de camudongos infectados por Schistosoma mansoni
The Schistosomiasis mansoni is the second human parasitosis more prevalent in the world, being in Brazil a problem of public health. The schistosomiasis alters lipid metabolism, promoting decrease in plasma levels of total cholesterol (TC), total phospholipids (TF) and triglycerides (TG). The praziquantel (PZQ) is the principal agent schistosomicidal employe
Publicado em: 2008
-
3. AvaliaÃÃo da atividade esquistossomicida do 3 - (4-clorobenzil)-5-(4-nitrobenzilideno)-imidazolidina-2,4-diona (FZ-4) e do Praziquantel frente a Schistosoma mansoni (cepa BH)
Failures, faced in schitossomiasis treatment with prazinquantel, are signing to the necessity to search new drugs to the treatment of this disease as well as monitoring its activity against strains of Schistosoma. The objective of the present work is to evaluate the schistossomicide activity in vivo of the Prazinquantel (PZQ) and the imidazolidine derived 3-
Publicado em: 2006
-
4. Novas 2-tioxo-imidazolidin-4-onas candidatas a fÃrmacos esquistossomicidas: sÃntese, elucidaÃÃo estrutural e atividade biolÃgica
The Schistosomiasis, infection broadly disseminated all over the world, is caused by species of the genus Schistosoma. According to reports of WHO, about 200.000 people die annually victims of this parasitiasis. The chemotherapy represents the principal instrument now for her control. Due the occurrence of Schistosoma mansoni isolated resistant to the only a
Publicado em: 2005