Igf I
Mostrando 1-12 de 637 artigos, teses e dissertações.
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1. Correlation of body mass index to Ghrelin and IGF-1 among children with short stature
Abstract Objective: To assess the BMI among children with Growth Hormone Deficiency (GHD) and Idiopathic Short Stature (ISS) and its correlation to ghrelin, Growth Hormone (GH), and Insulin-like Growth Factor-1 (IGF-1) levels. Methods: A cross-sectional descriptive study in which 42 patients attending the Pediatric endocrine clinic were enrolled, allocated
Jornal de Pediatria. Publicado em: 2022
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2. Molecular signature of immunological mechanism behind impaired endometrial receptivity in polycystic ovarian syndrome
ABSTRACT Objective: Despite the treatment of anovulation, infertility is still one of the main complications in PCOS women during reproductive age, which appears to be mainly due to impaired uterine receptivity. This study investigated the transcriptome profiles of endometrium in PCOS patients and healthy fertile individuals as the control group. Material
Archives of Endocrinology and Metabolism. Publicado em: 2022
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3. Insulina e IGF-1 no meio extensor de criopreservação seminal bovina
RESUMO Objetivou-se avaliar a condição metabólica e estrutural das células espermáticas bovinas após congelação, com adição prévia de IGF-I e insulina no meio diluidor seminal. Os ejaculados de seis touros Nelore foram submetidos a quatro tratamentos: controle; insulina (100µUI/mL); IGF-I (150ng/mL) e insulina + IGF-I (50µUI/mL e 75ng/mL, respec
Arq. Bras. Med. Vet. Zootec.. Publicado em: 2020-05
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4. Laboratory investigations in the diagnosis and follow-up of GH-related disorders
ABSTRACT In addition to auxiological, clinical and metabolic features measurements of growth hormone (GH) and insulin-like growth factor I (IGF-I) complement our tools in diagnosis and follow-up of GH-related disorders. While comparably robust during the pre-analytical phase, measurement and interpretation of concentrations of both hormones can be challengin
Arch. Endocrinol. Metab.. Publicado em: 10/01/2020
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5. Pegvisomant in acromegaly: a multicenter real-life study in Argentina
ABSTRACT Objective To describe the long term safety and efficacy of pegvisomant (PEGV), and the predictors of treatment response in patients with acromegaly in the real life setting. Subjects and methods We retrospectively reviewed the clinical, hormonal and radiological data of acromegalic patients treated with PEGV in 17 Argentine centers. Results Se
Arch. Endocrinol. Metab.. Publicado em: 22/08/2019
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6. Brazilian multicenter study on pegvisomant treatment in acromegaly
ABSTRACT Objective Investigate the therapeutic response of acromegaly patients to pegvisomant (PEGV) in a real-life, Brazilian multicenter study. Subjects and methods Characteristics of acromegaly patients treated with PEGV were reviewed at diagnosis, just before and during treatment. All patients with at least two IGF-I measurements on PEGV were include
Arch. Endocrinol. Metab.. Publicado em: 29/07/2019
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7. Clinical and functional variables can predict general fatigue in patients with acromegaly: an explanatory model approach
ABSTRACT Objective To evaluate whether hormonal profile, arterial function, and physical capacity are predictors of fatigue in patients with acromegaly. Subjects and methods: This is a cross-sectional study including 23 patients. The subjects underwent a Modified Fatigue Impact Scale (MFIS) assessment; serum growth hormones (GH) and IGF-1 measurements; pul
Arch. Endocrinol. Metab.. Publicado em: 25/04/2019
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8. Correlation analysis between short-term insulin-like growth factor-I and glucose intolerance status after transsphenoidal adenomectomy in acromegalic patients: a large retrospective study from a single center in China
ABSTRACT Objectives: Our study aimed to investigate the associations of glucose tolerance status with insulin-like growth factor-I (IGF-I) and other clinical laboratory parameters of acromegalic patients before and after the patients underwent transsphenoidal adenomectomy (TSA) by conducting a single-center, retrospective study. Subjects and methods: A tot
Arch. Endocrinol. Metab.. Publicado em: 21/03/2019
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9. Lack of association between genetic polymorphisms in IGF1 and IGFBP3 with twin births in a Brazilian population (Cândido Godói, Rio Grande do Sul)
Abstract Insulin-like growth factor (IGF-1) is an important peptide hormone involved in the reproduction and fetal development of mammals, and it is suggested that it may influence the human twinning rate. This study aimed to test such possible association, investigating the genetic polymorphisms IGF1 (CA)n and IGFBP3 rs2854744 in the population from Candido
Genet. Mol. Biol.. Publicado em: 29/11/2018
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10. Efeito da somatotrofina suína sobre o metabolismo, o tamanho testicular e a qualidade espermática de cachaços jovens
RESUMO O objetivo deste estudo foi determinar o efeito da administração de pST sobre o metabolismo, o tamanho testicular e a qualidade espermática de cachaços jovens. Foram usados leitões com 22 dias de idade, divididos em dois grupos: pST (n=30) e controle (n=30). O grupo pST foi submetido a injeções de pST (90µg/kg de peso vivo) a cada três dias a
Arq. Bras. Med. Vet. Zootec.. Publicado em: 2018-01
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11. Padronização da quantificação do fator de crescimento semelhante à insulina I (IGF-I) em plasma bovino por ELISA
RESUMO: Esse estudo teve como objetivo a padronização de um ensaio imunoenzimático competitivo (cELISA) in house para a determinação das concentrações plasmáticas do fator de crescimento semelhante a insulina I (IGF-I) total para a espécie bovina, utilizando o sistema de amplificação biotina-estreptavidina peroxidase. O IGF-I foi extraído das pro
Pesq. Vet. Bras.. Publicado em: 2017-12
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12. Expressão gênica de IGF-I e GHR no fígado e no músculo do peito de codornas de corte suplementadas com diferentes níveis de metionina em duas gerações sucessivas
RESUMO Este estudo foi desenvolvido com o objetivo de avaliar a expressão gênica do fator de crescimento semelhante à insulina I (IGF-I) e do receptor do hormônio do crescimento (GHR) no fígado e no músculo do peito de codornas de corte, alimentadas com dietas contendo diferentes níveis de suplementação de metionina, em duas gerações sucessivas. F
Arq. Bras. Med. Vet. Zootec.. Publicado em: 2017-02