Hypothalamic Action
Mostrando 1-12 de 137 artigos, teses e dissertações.
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1. Tadalafil: Protective Action against the Development of Multiple Organ Failure Syndrome
Abstract Introduction: Multiple organ failure syndrome (MOFS) is a pathology associated to unspecified and severe trauma, characterized by elevated morbidity and mortality. The complex inflammatory MOFS-related reactions generate important ischemia-reperfusion responses in the induction of this syndrome. Nitric oxide elevation, through the activation of cyc
Braz. J. Cardiovasc. Surg.. Publicado em: 2017-08
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2. Effects of the phytoestrogen genistein on the development of the reproductive system of Sprague Dawley rats
OBJECTIVES: Genistein is known to influence reproductive system development through its binding affinity for estrogen receptors. The present study aimed to further explore the effect of Genistein on the development of the reproductive system of experimental rats. METHODS: Eighteen post-weaning female Sprague Dawley rats were divided into the following groups
Clinics. Publicado em: 2013
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3. Tratamento com topiramato melhora a sensibilidade hipotalâmica à insulina em camundongos obesos / Topiramate improves insulin sigmalling the hypothalamus of mice on high-fat diet
Topiramate (TPM) is an anticonvulsant drug used for the treatment of epilepsy and prophylaxis of migraine. Weight loss is a frequently side effect reported in patients and animal models treated with TPM. In animal models topiramate may increase levels of hypothalamic corticotropic-releasing hormone (CRH), which is an anorexigenic neuropeptide and may decreas
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 18/11/2011
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4. Modulação do metabolismo muscular da glicose pela ação hipotalâmica da leptina / Modulation of glucose metabolism in muscle by the leptin hypothalamic action
Sobrepeso e obesidade são caracterizados por um aumento de tecido adiposo corpóreo, que resulta da interação entre muitos fatores, incluindo genéticos, metabólicos, comportamentais e ambientais. A obesidade está relacionada ao desenvolvimento de diabetes mellitus do tipo 2 (DM2). O principal mecanismo envolvido na associação entre obesidade e DM2 é
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 16/08/2011
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5. Dieta hiperlipídica poliinsaturada afeta as vias insulínica e inflamatória em hipotálamo de ratos/ / Hyperlipidic diet polyunsaturated affect the via insulinic and inflammatory in the hypothalamus of rats.
Insulin leads an anorexigenic response by acting on hypothalamic neurons. Studies suggest that resistance to its action is involved with diet-induced obesity (diet rich in saturated fatty acids) and its association with hypothalamic inflammation. However, the effects of polyunsaturated fatty acids on insulin and inflammatory signaling pathways are poorly und
Publicado em: 2010
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6. Temporal evaluation of c-fos expression in amygdaloid and hypothalamic areas following experimental tooth movement in rats / Avaliação temporal da expressão da proteína FOS em áreas amigdalóides e hipotalâmicas após movimentação dentária experimental em ratos
In the accomplishment of the orthodontic treatment, it is described that the pain happens immediately after the application of orthodontic forces and disappears after few days. Regarding the neural pathways involved in the sensorial mediation of the orthodontic movement (OM) few are the studies that approach this theme, and in the last decades solid founds d
Publicado em: 2008
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7. Imprinting estrogenico : efeito sobre a expressão do receptor de androgeno no hipotalamo de ratos Wistar / Effects of estrogenic imprinting on the androgen receptor expression in the hypothalamus of Wistar rats
In male rats, complete reproductive function is critically dependent on adequate estrogen action at different levels of the hypothalamic-pituitary-gonadal axis. The administration of high doses during the period of sexual differentiation results in irreversible alterati ns in the male reproductive system. In brief, the estrogens have anti-androgenic effects
Publicado em: 2008
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8. Reduction hypothalamic of PTP-1B improves the sensibility to the insulin and leptin in normal and obese rats / Redução hipotalamica da PTP-1B melhora a sensibilidade a insulina e leptina em ratos normais e obesos
Protein tyrosine phosphatase (PTP1B) has been implicated in the negative regulation of insulin and leptin signaling. PTP1B knockout mice are hypersensitive to insulin and leptin and resistant to obesity when fed a high-fat diet. We investigated the role of hypothalamic PTP1B in the regulation of food intake, insulin and leptin actions and signaling in rats t
Publicado em: 2007
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9. Redução hipotalamica da PTP-1B melhora a sensibilidade a insulina e leptina em ratos normais e obesos / Reuction hypothalamic of PTP-1B improves the sensibility to the insulin and leptin in normal and obese rats
Protein tyrosine phosphatase (PTP1B) has been implicated in the negative regulation of insulin and leptin signaling. PTP1B knockout mice are hypersensitive to insulin and leptin and resistant to obesity when fed a high-fat diet. We investigated the role of hypothalamic PTP1B in the regulation of food intake, insulin and leptin actions and signaling in rats t
Publicado em: 2007
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10. Novel mechanisms of growth hormone regulation: growth hormone-releasing peptides and ghrelin
Growth hormone secretion is classically modulated by two hypothalamic hormones, growth hormone-releasing hormone and somatostatin. A third pathway was proposed in the last decade, which involves the growth hormone secretagogues. Ghrelin is a novel acylated peptide which is produced mainly by the stomach. It is also synthesized in the hypothalamus and is pres
Brazilian Journal of Medical and Biological Research. Publicado em: 2006-08
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11. Inter-relação entre as vias de transmissão do sinal de insulina e leptina em hipotalamo e figado de ratos
Insulin and leptin have overlapping effects in the control of energy homeostasis and glucose metabolism, but the molecular basis of this synergism is unknown. Insulin signals through a receptor tyrosine kinase that phosphorylates and activates the docking proteins IRSs (insulin receptor substrates), whereas the leptin receptor and its associated protein tyro
Publicado em: 2002
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12. Role of the hypothalamic pituitary adrenal axis in the control of the response to stress and infection
The release of adrenocorticotropin (ACTH) from the corticotrophs is controlled principally by vasopressin and corticotropin-releasing hormone (CRH). Oxytocin may augment the release of ACTH under certain conditions, whereas atrial natriuretic peptide acts as a corticotropin release-inhibiting factor to inhibit ACTH release by direct action on the pituitary.
Brazilian Journal of Medical and Biological Research. Publicado em: 2000-10