Hypospadias Embryology
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1. Medroxyprogesterone acetate administered during pre-natal period causes hypospadia in male and virilization in female mice / "Acetato de medroxiprogesterona administrado em período pré-natal induz hipospádia em machos e virilização em fêmeas de camundongos"
In vitro fertilization (IVF) has been associated with an increase incidence of hypospadias. IVF protocols require the maternal use of progesterone which may be a factor in causing hypospadias. To test these hypotheses in an animal model, we describe the effects of maternal progesterone exposure on genital development in mice. Medroxyprogesterone acetate (MPA
Publicado em: 2005