Human S100a12
Mostrando 1-12 de 185 artigos, teses e dissertações.
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1. Chemical Prospection of Qualea grandiflora Mart. Fruit and Stem Extracts and Their in vitro and in vivo Antiplasmodial Activity
Qualea grandiflora Mart. (“pau-terra”) is a medicinal plant symbolic from Cerrado biome. Qualea species reportedly have antiparasitic properties, but their active compounds have yet to be identified. In this study, we investigated the antiplasmodial activity of Q. grandiflora fruit and stem extracts against Plasmodium falciparum. The polar extracts of bo
J. Braz. Chem. Soc.. Publicado em: 2020-07
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2. Triatomine dispersion rates and their association with socioeconomic and environmental conditions in Northeastern Brazil, from 2009 to 2013
ABSTRACT Triatomines are vectors of Trypanosoma cruzi , the etiological agent of Chagas disease, which affects between 6 and 12 million people in Latin America, with an incidence rate of 12 thousand cases per year. In the Ceara State, the predominance of the caatinga biome, coupled with a large rural area with precarious human habitations, provides several s
Rev. Inst. Med. trop. S. Paulo. Publicado em: 12/09/2019
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3. Ortho-nitrobenzyl derivatives as potential anti-schistosomal agents
ABSTRACT In the search for new anti-schistosomal agents, a series of fifteen ortho-nitrobenzyl derivatives was assayed in vitro against both the schistosomulum (somule) and adult forms of Schistosoma mansoni. Compounds 8 and 12 showed significant activity against somules at low micromolar concentrations, but none was active against adults. The SAR demonstrat
Braz. J. Pharm. Sci.. Publicado em: 26/07/2018
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4. ISOLATION OF CYTOTOXIC NEOLIGNANS FROM Saururus cernuus L. (SAURURACEAE) USING IONIC LIQUID IN THE MICROWAVE ASSISTED EXTRACTION (MAE)
In the present work, dried leaves of Saururus cernuus (Saururaceae) were subjected to extraction using an ionic liquid (1-butyl-3-methylimidazolium bromide - BMImBr) in the microwave assisted extraction (MAE). The obtained extract was partitioned using n-hexane and cytotoxicity activity of this organic phase against murine melanoma cell line (B16F10-Nex2) wa
Quím. Nova. Publicado em: 2018-07
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5. Phenotypic and Genotypic Antibiotic Resistance of Salmonella from Chicken Carcasses Marketed at Ibague, Colombia
ABSTRACT Salmonella enterica is responsible for alimentary toxic infections associated with the consumption of contaminated poultry products and the antimicrobial resistant patterns of Salmonella circulating in the Tolima region are currently unknown. To address this issue, both the phenotype and genotype antibiotic resistance patterns of 47 Salmonella isola
Rev. Bras. Cienc. Avic.. Publicado em: 2017-06
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6. Preventive effect of toothpastes with MMP inhibitors on human dentine erosion and abrasion in vitro
ABSTRACT The use of gels and mouthrinses with MMP inhibitors (chlorhexidine, and green tea extract) was shown to prevent erosive wear. The aim of this study was to analyze the protective effect of toothpastes containing MMP inhibitors on dentine loss induced by erosion in vitro. Material and Methods Five groups each containing 12 specimens of human root de
J. Appl. Oral Sci.. Publicado em: 2016-02
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7. Human sepsis-associated Escherichia coli (SEPEC) is able to adhere to and invade kidney epithelial cells in culture
The adhesins of extraintestinal pathogenic Escherichia coli are essential for mediating direct interactions between the microbes and the host cell surfaces that they infect. Using fluorescence microscopy and gentamycin protection assays, we observed that 49 sepsis-associated E. coli (SEPEC) strains isolated from human adults adhered to and invaded Vero cells
Brazilian Journal of Medical and Biological Research. Publicado em: 2012-05
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8. Produção, isolamento e identificação de metabólito com atividade citotóxica de cultura de Streptomyces carpaticus / Production, isolation and identification of citotoxic activity metabolite of streptomyces carpaticus culture
This study addresses the production, isolation and identification of the substance present in culture broth of Streptomyces carpaticus which showed high biological activity against human tumor cell lines HL-60 (promyelocytic leukemia), MDA-MB 435 (breast carcinoma ), HCT-8 (colon carcinoma), SF-295 (glioblastoma). Cultures of Streptomyces carpaticus in cultu
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 21/09/2011
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9. PADRÃES E TENDÃNCIAS DE MORBIMORTALIDADE E SOBREVIDA EM CRIANÃAS COM AIDS NO BRASIL / PATTERNS AND TRENDS OF MORTALITY AND SURVIVAL IN BRAZILIAN CHILDREN WITH AIDS
A infecÃÃo pelo HIV/aids em crianÃas vem sendo eliminada como problema de saÃde pÃblica em paÃses desenvolvidos, mas mantÃm elevada carga de morbimortalidade naqueles em desenvolvimento. O Brasil se destaca pela polÃtica consistente de controle, especialmente pela adoÃÃo universal/gratuita da HAART em 1996. Esta tese visa caracterizar padrÃes e te
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/03/2011
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10. Sensitive determination of perphenazine in pharmaceuticals and human serum by flow injection chemiluminescence method using [Ru(phen)3]2+-ce(IV) system and a chemometrical optimization approach
Este artigo descreve um método de quimioluminescência (CL) simples, rápido e sensível para a determinação de perfenazina usando sistema de injeção em fluxo (FI). Todas as variáveis que podem afetar a resposta do método CL foram otimizadas empregando planejamento composto central (CCD) para o planejamento experimental e metodologia de superfície de
Journal of the Brazilian Chemical Society. Publicado em: 2011-01
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11. Estudos da dinâmica estrutural da proteína ligante de cálcio S100A12 humana e da lisozima T4 / Structural dynamics studies of human calcium binding protein S100A12 and T4 lysozyme
The work presented here was conceived with two main objectives. The first one, more general, involved the implementation of a new methodology for the study of conformational changes in proteins, i.e., its structural dynamics. The technique of Site-directed Spin Labeling combined with Electronic Paramagnetic Resonance (SDSL-EPR) are the pillars of this new me
Publicado em: 2011
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12. Beneficial effects of exercise training (treadmill) on insulin resistance and nonalcoholic fatty liver disease in high-fat fed C57BL/6 mice
C57BL/6 mice develop signs and symptoms comparable, in part, to the human metabolic syndrome. The objective of the present study was to evaluate the effects of exercise training on carbohydrate metabolism, lipid profile, visceral adiposity, pancreatic islet alterations, and nonalcoholic fatty liver disease in C57BL/6 mice. Animals were fed one of two diets d
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-05