Hre
Mostrando 13-24 de 53 artigos, teses e dissertações.
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13. Preparation, characterization, and application of trimetalic catalysts for direct ethanol fuel cells: Pt-Ru-Sn/C / Preparação, caracterização e aplicação de catalisadores trimetálicos para a oxidação de etanol em célula a combustível direta: Pt-Ru-Sn/C
This work aimed at developing a method for the obtention of carbon-supported Pt nanocatalysts modified with Rhutenium and Tin, which were evaluated for ethanol eletrooxidation in direct fuel cells. To obtain these catalysts, we employed the Pechini method, which consists in the decomposition of a polymeric precursor. Many nanocatalysts containing various PtR
Publicado em: 2007
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14. Clonagem e expressão do fator 1 humano induzível por hipóxia (HIF-1) na levedura Saccharomyces cerevisiae
The hypoxia-inducible factor-1 (HIF-1) is a central regulator in the response to changes in oxygen concentration and plays an important role in physiological and pathological processes in humans. This transcription factor is expressed when mammalian cells are subjected to hypoxia and activates transcription of over 70 oxygen-regulated target genes. HIF-1 is
Publicado em: 2006
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15. Utilização biologica do ferro do feijão "carioca 8 O S.H." (Phaseolus vulgaris, L.), na repleção da hemoglobina de ratos anemicos
A anemia por deficiência de ferro permanece como o maior problema nutricional em todo o mundo, atingindo particular mente crianças entre seis meses e três anos de idade. O objetivo do presente trabalho foi avaliar a utilização do ferro de um novo cultivar de feijão, Carioca 80 S.H. ,na forma de farinha do feijão integral e da papa do feijão, como usu
Publicado em: 1990
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16. HreP, an In Vivo-Expressed Protease of Yersinia enterocolitica, Is a New Member of the Family of Subtilisin/Kexin-Like Proteases
The role of proteases in pathogenesis is well established for several microorganisms but has not been described for Yersinia enterocolitica. Previously, we identified a gene, hreP, which showed significant similarity to proteases in a screen for chromosomal genes of Y. enterocolitica that were exclusively expressed during an infection of mice. We cloned this
American Society for Microbiology.
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17. CArG binding factor A (CBF-A) is involved in transcriptional regulation of the rat Ha-ras promoter
In the present study we identified a positive transcriptional element within the rat Ha-ras promoter previously known as Ha-ras response element (HRE) and identified a trans-acting factor that binds HRE sequences in rat mammary cells. To identify the binding protein we employed sequence specific DNA affinity chromatography. Amino acid sequence analysis of th
Oxford University Press.
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18. The hormone response element of the mouse mammary tumour virus DNA mediates the progestin and androgen induction of transcription in the proviral long terminal repeat region.
Mouse mammary tumour virus (MMTV) gene expression has been shown to be regulated by glucocorticoids. A hormone response element (HRE) located between -202 and -59 upstream of the start of transcription in the long terminal repeat (LTR) region of the proviral DNA is required for this induction. We have investigated the role played by the HRE in the induction
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19. Antibacterial activity of HRE 664, a new parenteral penem.
The antibacterial activity of the new penem compound HRE 664 was evaluated in 451 clinical isolates, including ampicillin-resistant members of the family Enterobacteriaceae, Acinetobacter spp., Haemophilus influenzae, Staphylococcus aureus, and beta-hemolytic streptococci, and compared with those of piperacillin, ceftazidime, ceftriaxone, aztreonam, imipenem
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20. Altered DNA binding specificity of Arnt by selection of partner bHLH–PAS proteins
The Ah receptor (AhR) and HLF are transcription factors involved in xenobiotic metabolism and hypoxic response, respectively. AhR and HLF heterodimerize with Arnt as the common partner, and bind to asymmetric E-boxes termed XRE and HRE, respectively. In order to investigate nucleotide preference of the heterodimers, reporter plasmids with oligonucleotides fo
Oxford University Press.
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21. Adeno-associated viral vector-mediated hypoxia response element-regulated gene expression in mouse ischemic heart model
Intramyocardial injection of genes encoding angiogenic factors could provide a useful approach for the treatment of ischemic heart disease. However, uncontrolled expression of angiogenic factors in vivo may cause some unwanted side effects, such as hemangioma formation, retinopathy, and arthritis. It may also induce occult tumor growth and artherosclerotic p
The National Academy of Sciences.
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22. Expression of maspin in prostate cells is regulated by a positive Ets element and a negative hormonal responsive element site recognized by androgen receptor
Prostate cancer is the most common cancer in men. The molecular mechanisms leading to its development are poorly understood. Maspin is a tumor-suppressing serpin expressed in normal breast and prostate epithelium. We have found that expression of maspin in normal and carcinoma-derived prostate epithelial cells is differentially regulated at the transcription
The National Academy of Sciences of the USA.
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23. Differential gene regulation by the SRC family of coactivators
SRCs (steroid receptor coactivators) are required for nuclear receptor-mediated transcription and are also implicated in the transcription initiation by other transcription factors, such as STATs and NFκB. Despite phenotypic manifestations in gene knockout mice for SRC-1, GRIP1, and AIB1 of the SRC (Steroid Receptor Coactivator) family indicating their diff
Cold Spring Harbor Laboratory Press.
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24. Inhibition of vascular endothelial growth factor with a sequence-specific hypoxia response element antagonist
Vascular endothelial growth factor (VEGF) and its receptors have been implicated as key factors in tumor angiogenesis that are up-regulated by hypoxia. We evaluated the effects of DNA-binding small molecules on hypoxia-inducible transcription of VEGF. A synthetic pyrrole-imidazole polyamide designed to bind the hypoxia response element (HRE) was found to dis
National Academy of Sciences.