Hplc Uv
Mostrando 13-24 de 430 artigos, teses e dissertações.
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13. A newly validated HPLC–DAD-UV method to study the effects of medicinal plants extracts, fractions and isolate compounds on gastric emptying in rodents
Abstract In this study, we developed and validated a chromatographic method by High-performance Liquid Chromatography coupled to Diode-Array Ultraviolet Detector for quantification of acetaminophen in small volumes of plasma. This analytical method is particularly suitable for studies of gastric emptying time and pharmacokinetics in small rodents. Orally adm
Rev. bras. farmacogn.. Publicado em: 09/12/2019
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14. A New Electrochemical Platform Based on a Polyurethane Composite Electrode Modified with Magnetic Nanoparticles Coated with Molecularly Imprinted Polymer for the Determination of Estradiol Valerate in Different Matrices
A polyurethane composite electrode modified with magnetic nanoparticles (mag; Fe3O4) coated with molecularly imprinted polymers (MIPs) was developed for the electrochemical determination of estradiol valerate. Chemical and morphological analyses of the mag-MIP were performed using scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (E
J. Braz. Chem. Soc.. Publicado em: 24/10/2019
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15. Validated analytical study of the effect of Lycopene on the pharmacokinetics of Paracetamol and Chlorzoxazone in rats
Lycopene was reported to influence some cytochrome P450 enzymes activity. The present study investigates the effect of lycopene on the pharmacokinetics of paracetamol and chlorzoxazone. Lycopene (20 mg/kg) was intra-peritoneally administered to two groups of rats for eight consecutive days and two other groups were given vehicle. On the eighth day, chlorzoxa
Braz. J. Pharm. Sci.. Publicado em: 03/10/2019
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16. Midazolam and haloperidol for palliative sedation: physicochemical stability and compatibility of parenteral admixtures
This study was done to determine the time while the binary admixtures with midazolam and haloperidol drugs are administered by perfusion to the patients in the clinical routine. Samples with different concentrations of both drugs were prepared following the usual clinical practice. Solvents used were 0.9 % sodium chloride solution and 5% dextrose, and viaflo
Braz. J. Pharm. Sci.. Publicado em: 09/09/2019
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17. Chemical composition of propolis extract and its effects on epirubicin-induced hepatotoxicity in rats
ABSTRACT Propolis is a natural substance, produced by honeybees from the resin of various plants. The purpose of this study was to determine the chemical composition and evaluate the hepatoprotective effect of ethyl acetate extract of propolis from Tigzirt, against the toxicity induced by epirubicin which is a anticancer agent, and belongs to the family of a
Rev. bras. farmacogn.. Publicado em: 26/08/2019
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18. Chemical Constituents and Pharmacology properties of Aristolochia triangularis: a south brazilian highly-consumed botanical with multiple bioactivities
Abstract: Aristolochia triangularis Cham., is one of the most frequently used medicinal plant in Southern Brazil. Preparations containing the leaves and/or stems are traditionally used as anti-inflammatory, diuretic, as well as antidote against snakebites. This study screened A. triangularis extracts, fractions and isolated compounds for different bioactivit
An. Acad. Bras. Ciênc.. Publicado em: 12/08/2019
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19. HPLC profile and simultaneous quantitative analysis of tingenone and pristimerin in four Celastraceae species using HPLC-UV-DAD-MS
ABSTRACT A validated method for the identification and authentication of tingenone and pristimerin was developed using HPLC. The chromatographic profile analysis was combined with simultaneous quantification in Crossopetalum rhacoma Crantz, Cassine xylocarpa Vent, Semialarium mexicanum (Miers) Mennega (known as cancerina), and Maytenus phyllanthoides Benth,
Rev. bras. farmacogn.. Publicado em: 27/05/2019
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20. Comparison and correlation analysis of flavonoids and chlorogenic acid contents in different strains of Acer truncatum
Abstract The morphological characteristics, total flavonoid content (TFC) and chlorogenic acid (CGA) contents of leaves from different strains of Acer truncatum were analyzed with the goal of providing guidance for the development and utilization of Acer truncatum leaves (ATLs) and a selection system for the medicinal cultivar of Acer truncatum species. The
Food Sci. Technol. Publicado em: 30/07/2018
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21. Influence of drying methods on cocoa (Theobroma cacao L.): antioxidant activity and presence of ochratoxin A
Abstract This work aimed to evaluate the performance of different drying methods in the development of phenolic compounds, methylxanthines, and antioxidant activity in cocoa bean and to evaluate the presence of ochratoxin A (OTA). Antioxidant activity was determined using DPPH, FRAP, ORAC and β-carotene-linoleic acid assays. Phenolic compounds and methylxa
Food Sci. Technol. Publicado em: 26/07/2018
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22. Complexation and enhancement of temozolomide solubility with cyclodextrins
ABSTRACT Temozolomide is a poorly soluble anti-cancer drug used in the treatment of some brain cancers. Following literature reports about the enhancement of solubility and stability for these kinds of drugs upon complexation with cyclodextrins, we aimed to form an inclusion complex between temozolomide and the different types of cyclodextrins (CDs) to enhan
Braz. J. Pharm. Sci.. Publicado em: 26/07/2018
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23. Determination of Alkyl Esters Content by Gas Chromatography: Validation of Method Based on Short Column and Response Factor
In this study an analytical method, based on gas chromatography with flame ionization detection, using a short column and response factor (GCSCRF), was validated for the quantification of fatty acid alkyl esters (methylic or ethylic). During the validation process, the proposed method was employed to analyze twenty samples of fatty acid methyl esters and fat
J. Braz. Chem. Soc.. Publicado em: 2018-06
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24. EXTRAÇÃO EM FASE SÓLIDA DE RESÍDUOS DE AGROTÓXICOS DE ÁGUA SUPERFICIAL, EMPREGANDO UM SORVENTE DE MENOR RETENÇÃO
Solid phase extraction (SPE) is one of the main sample preparation techniques. However, the cost of cartridges and the strong retention of hydrophobic compounds in traditional solid phases are limiting factors for their use. This paper describes the application of lab-made SPE cartridges with low retention material as solid phase, Si(PDAS) - poly(dimethyl-co
Quím. Nova. Publicado em: 2018-06