Host Virus Relationship
Mostrando 1-12 de 179 artigos, teses e dissertações.
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1. Overexpression of miR-484 and miR-744 in Vero cells alters Dengue virus replication
BACKGROUND Dengue is considered one of the world’s most important mosquito-borne diseases. MicroRNAs (miRNAs) are small non-coding single-stranded RNAs that play an important role in the regulation of gene expression in eukaryotes. Although miRNAs possess antiviral activity against many mammalian-infecting viruses, their involvement in Dengue virus (DENV
Mem. Inst. Oswaldo Cruz. Publicado em: 02/03/2017
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2. Prevalence of IFNL3 gene polymorphism among blood donors and its relation to genomic profile of ancestry in Brazil
ABSTRACT The recent development of interferon-free regimens based on direct-acting antivirals for the treatment of chronic hepatitis C virus infection has benefited many but not all patients. Some patients still experience treatment failure, possibly attributed to unknown host and viral factors, such as IFNL3 gene polymorphism. The present study assessed the
Braz J Infect Dis. Publicado em: 2016-12
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3. Interspecific transmission of small ruminant lentiviruses from goats to sheep
This study was conducted in order to evaluate the transmission of caprine lentivirus to sheep using different experimental groups. The first one (colostrum group) was formed by nine lambs receiving colostrum from goats positive for small ruminant lentiviruses (SRLV). The second group (milk group) was established by nine lambs that received milk of these g
Braz. J. Microbiol.. Publicado em: 21/07/2015
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4. Mycobacterium fortuitum-related lymphadenitis associated with the varicella-zoster virus
Lymphadenitis caused by non-tuberculous mycobacteria is an uncommon manifestation in immunocompetent individuals. Here, we report a case of Mycobacterium fortuitum infection in a previously healthy 9-year-old patient who developed cervical lymphadenitis evolving to a suppurative ulcer associated with a varicella-zoster virus infection. We discuss the relatio
Rev. Soc. Bras. Med. Trop.. Publicado em: 2014-01
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5. The role of human T cell lymphotrophic virus type 1, hepatitis B virus and hepatitis C virus coinfections in leprosy
Leprosy spectrum and outcome is associated with the host immune response against Mycobacterium leprae. The role of coinfections in leprosy patients may be related to a depression of cellular immunity or amplification of inflammatory responses. Leprosy remains endemic in several regions where human T cell lymphotrophic virus type 1 (HTLV-1), hepatitis B virus
Mem. Inst. Oswaldo Cruz. Publicado em: 2012-12
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6. Desmodus rotundus and Artibeus spp. bats might present distinct rabies virus lineages
In Brazil, bats have been assigned an increasing importance in public health as they are important rabies reservoirs. Phylogenetic studies have shown that rabies virus (RABV) strains from frugivorous bats Artibeus spp. are closely associated to those from the vampire bat Desmodus rotundus, but little is known about the molecular diversity of RABV in Artibeus
Braz J Infect Dis. Publicado em: 2012-12
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7. In vitro expression and antiserum production against the movement protein of Citrus leprosis virus C (CiLV-C)
Citrus leprosis, caused by Citrus leprosis virus C (CiLV-C), is currently considered the most important viral disease in the Brazilian citrus industry due to the high costs required for the chemical control of its vector, the mite Brevipalpus phoenicis. The pathogen induces a non-systemic infection and the disease is characterized by the appearance of locali
Tropical Plant Pathology. Publicado em: 2012-04
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8. Modelagem molecular de uma série de compostos inibidores da enzima integrase do vírus HIV-1 / Molecular modelling for a series of integrase HIV-I inhibitors
An essential step in the HIV life cycle is integration of the viral DNA into the host chromosome. This step is catalyzed by a 32-kDa viral enzyme HIV integrase (IN). HIV-1 IN is an important and validated target, and the drugs that selectively inhibit this enzyme, when used in combination with reverse transcriptase (RT) and protease (PR) inhibitors, are beli
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 20/07/2011
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9. Mechanisms of virus resistance and antiviral activity of snake venoms
Viruses depend on cell metabolism for their own propagation. The need to foster an intimate relationship with the host has resulted in the development of various strategies designed to help virus escape from the defense mechanisms present in the host. Over millions of years, the unremitting battle between pathogens and their hosts has led to changes in evolu
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2011
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10. Heterogeneity in extracellular nucleotide hydrolysis among clinical isolates of Trichomonas vaginalis
Trichomonas vaginalis is a parasitic protozoan that causes trichomonosis, a sexually-transmitted disease, with serious sequelae to women and men. As the host–parasite relationship is complex, it is important to investigate biochemical aspects of the parasite that contribute to our understanding of trichomonal biology and pathogenesis. Nucleoside triphospha
Publicado em: 2011
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11. Genetic analysis of the porcine group B rotavirus NSP2 gene from wild-type Brazilian strains
Group B rotaviruses (RV-B) were first identified in piglet feces, being later associated with diarrhea in humans, cattle, lambs, and rats. In human beings, the virus was only described in China, India, and Bangladesh, especially infecting adults. Only a few studies concerning molecular analysis of the RV-B NSP2 gene have been conducted, and porcine RV-B has
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-01
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12. Esteato-hepatite não alcoólica e esteatose em hepatite crônica pelo vírus C: prevalência e relações entre dados demográficos e clínico-laboratoriais com parâmetros histopatológicos / Nonalcoholic steatohepatitis and steatosis in chronic hepatitis C: prevalence and the relationship between demographic, clinical and laboratory data with histopathological parameters
Chronic hepatitis C is the leading cause of progressive liver damage and related complications, such as cirrhosis and primary hepatocellular carcinoma. Fibrosis stage and necro-inflammatory activity grade are good predictors of disease progression in chronic hepatitis C (CHC).The global epidemic of obesity and diabetes are associated with the increasing inci
Publicado em: 2010