Hla Typing
Mostrando 13-24 de 188 artigos, teses e dissertações.
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13. Effect of the human leukocyte antigen HLA-DRB1 and anti-cyclic citrullinated peptide on the outcome of rheumatoid arthritis patients
Our objective was to determine whether the presence of the human leukocyte antigen HLA-DRB1 locus is associated with production of anti-cyclic citrullinated peptide antibodies (anti-CCP Abs) and to what extent they are associated with increased susceptibility to and severity of rheumatoid arthritis (RA) in Egyptian patients. Twenty-nine RA patients gave info
Brazilian Journal of Medical and Biological Research. Publicado em: 2009-09
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14. Estudo epidemiológico da infecção por herpesvírus 8 humano (HHV-8) em população indígena da Amazônia brasileira / Epidemiological study of Human herpesvirus 8 infection (HHV-8) in the Amerindian population from Brazilian Amazon
The human herpesvirus 8 (HHV-8) is endemic in Africa and Amerindian populations from Amazon region. The infection in those populations occurs during childhood and, in Africa, involves a close contact in intrafamilial environment. Several studies confirm the geographical distribution of different subtypes of HHV-8, and the subtype E is typical of the Amerindi
Publicado em: 2009
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15. HLA-DRB1 alleles in juvenile-onset systemic lupus erythematosus: renal histologic class correlations
Human leukocyte antigens (HLA) DRB1*03 and DRB1*02 have been associated with systemic lupus erythematosus (SLE) in Caucasians and black populations. It has been observed that certain HLA alleles show stronger associations with SLE autoantibodies and clinical subsets, although they have rarely been associated with lupus renal histologic class. In the present
Brazilian Journal of Medical and Biological Research. Publicado em: 2007-04
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16. Perfil do HLA de classe II de pacientes com hepatite C e características de hepatite auto-imune / Class II HLA profile oh hepatitis C patients with autoimmune hepatitis features
Introduction: HCV chronic infection is an epidemic condition that affects more than 170 million of people around the world, and often is associated with autoimmunity phenomena. The role of HLA class II alleles has been studied in many autoimmune diseases. Aim: To investigate the presence of laboratory markers of autoimmunity and compatible anatomo pathologic
Publicado em: 2006
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17. Typing class I HLA-A gene using a nested PCR-RFLP procedure
In order to detect several new HLA-A class I alleles that have been described since 1998, the original PCR-RFLP method developed to identify the 78 alleles recognized at that time at high resolution level was adapted by us for low and medium resolution levels using a nested PCR-RFLP approach. The results obtained from blood samples of 23 subjects using both
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-06
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18. Caracterização do polimorfismo dos alelos HLA de classe I e nos microssatelites do fator de necrose tumoral em pacientes brasileiros com psoriase vulgar
Introduction - Psoriasis is a genetic chronic inflammatory skin disorder with genes involved in disease predisposition located within the highly polymorphic Major Histocompatibility Complex (MHC) region on the chromosome 6p21.3. The goal of the present study was to identify, evaluate distribution and determine genetic associations of HLA class I genes and Tu
Publicado em: 2005
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19. Association of human leukocyte antigen DQ1 and dengue fever in a white Southern Brazilian population
Dengue is an infectious disease of viral etiology transmitted by the mosquitoes Aedes aegypti, A. albopictus, and A. scutellaris. It can develop either as a benign form or as a severe hemorrhagic form. Previous work showed an association of the hemorrhagic form with human leukocyte antigens (HLA), suggesting a role of genetic factors in disease susceptibilit
Memórias do Instituto Oswaldo Cruz. Publicado em: 2004-10
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20. Correlação clinica e imunologica do microquimerismo do sangue periferico e impacto dos fatores imunogeneticos em pacientes brasileiros apos o transplante de figado
Background - In liver transplant, a large number of studies has demonstrated allogeneic microclrimerism. Clinical and immunological implications remain inconclusive; on the other hand, influence of HLA mismatch and donor alloreactivity also remain conf1icting. On the basis of these controversial data, the present study analyzed the presence of allogeneic mic
Publicado em: 2004
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21. The availability of full match sibling donors and feasibility of allogeneic bone marrow transplantation in Brazil
The feasibility of allogeneic bone marrow transplantation (alloBMT) in a developing country has not yet been demonstrated. Many adverse factors including social and economic limitations may reduce the overall results of this complex and expensive procedure. Our objective was to characterize the most important clinical, social and economic features of candida
Brazilian Journal of Medical and Biological Research. Publicado em: 2003-03
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22. Haplótipos HLA mais freqüentes em doadores voluntários de medula óssea de Curitiba, Paraná
Bone Marrow Transplant (BMT) is a therapy used to treat patients with hematological diseases. The success of the transplant relies on a HLA match between host and donor. The HLA is located in the Major Histocompatibility Complex in the 6p12.3 region of the chromosome 6. The HLA gene products are involved in the immunomodulation of the immune response due to
Revista Brasileira de Hematologia e Hemoterapia. Publicado em: 2002-12
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23. HLA-DQA1 allele typing by nonisotopic PCR-LIS-SSCP
In the present study we used a simple and reliable method for HLA-DQA1 allele typing based on the single-stranded conformation polymorphism (SSCP) properties of DNA molecules obtained by PCR. The technique consists of PCR amplification of a DNA fragment comprising the second exon of the HLA-DQA1 gene, amplicon denaturation using a low ionic strength solution
Brazilian Journal of Medical and Biological Research. Publicado em: 2001-07
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24. Diagnostico imunologico e efeito de imunizações com linfocitos em pacientes com aborto espontaneo recorrente
t: Pregnancy can be considered as a very successful all graft, but the underlying mechanism is not yet completely understood. HLA all tigens compatibility is very important in c1inic transplant due to their all ore cognition by immune system. Nevertheless, genetic differences between maternal and paternal HLA antigens seem to be an important factor for impla
Publicado em: 1998