Histocompatibility Antigens
Mostrando 1-12 de 840 artigos, teses e dissertações.
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1. Investigation of MHC gamma block C4A and C4B polymorphisms in unrelated hematopoietic stem cell transplantation
ABSTRACT Background: Immunological life-threatening complications frequently occur in post-hematopoietic stem cell transplantation (HSCT), despite matching recipient and donor (R/D) pairs for classical human leukocyte antigens (HLA). Studies have shown that R/D non-HLA disparities within the major histocompatibility complex (MHC) are associated with adverse
Hematol., Transfus. Cell Ther.. Publicado em: 2020-09
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2. Human leukocyte antigen allele linkage disequilibrium and haplotype structure in volunteer bone marrow donors of Paraná State
Abstract Background Bone marrow transplantation has been used in the treatment of various diseases, especially hematologic diseases. The success of this treatment, among other factors, requires human leukocyte antigens (HLA) compatibility between patient and donor. Knowing the human leukocyte antigens allele group and haplotype frequencies as well as the li
Rev. Bras. Hematol. Hemoter.. Publicado em: 2017-09
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3. Comparative study of lymphocytes from individuals that were vaccinated and unvaccinated against the pandemic 2009-2011 H1N1 influenza virus in Southern Brazil
ABSTRACTINTRODUCTION:While no single factor is sufficient to guarantee the success of influenza vaccine programs, knowledge of the levels of immunity in local populations is critical. Here, we analyzed influenza immunity in a population from Southern Brazil, a region with weather conditions that are distinct from those in the rest of country, where influenza
Rev. Soc. Bras. Med. Trop.. Publicado em: 2015-10
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4. Freqüências de alelos e haplótipos HLA A, -B e DRB1 em uma amostra de doadores voluntários de medula óssea do estado do Rio Grande do Sul
As moléculas HLA (Human Leucocyte Antigens) são proteínas codificadas por genes altamente polimórficos localizados na região do MHC (Major Histocompatibility Complex) no braço curto do cromossomo 6 humano. Elas estão envolvidas em processos de resposta imunológica, sendo responsáveis pela apresentação de antígenos aos linfócitos T. O sistema HLA
Publicado em: 2011
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5. Heterotopic transplantation of glycerin-preserved trachea : effect of respiratory epithelium desquamation on acute rejection
An effective preservation method and decreased rejection are essential for tracheal transplantation in the reconstruction of large airway defects. Our objective in the present study was to evaluate the antigenic properties of glycerin-preserved tracheal segments. Sixty-one tracheal segments (2.4 to 3.1 cm) were divided into three groups: autograft (N = 21),
Publicado em: 2010
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6. Artrite reumatoide em Afro-brasileiros : "O papel do HLA" / Rheumatoid arthritis in Afro-brazilians : "The role of HLA"
The association of histocompatibility antigens with Rheumatoid Arthritis (RA) comes being demonstrated in innumerable studies. However, the evaluation in afrodescendents populations still little was studied. The aim of this study has been to determine the frequency of HLA-DRB1 alleles, and the contributions of the polymorphism of these alleles in the suscept
Publicado em: 2009
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7. Mucous-cutaneuos hyalinosis : the clinical and histocompatibility antigens study / Hialinose cutaneo-mucosa : estudo clinico e das especificidades HLA
A hialinose cutâneo-mucosa (HCM) é uma dermatose autossômica recessiva rara, congênita, de aparecimento precoce na infância. Caracteriza-se por deposição de material hialino, que se acumula na pele e mucosas. Foram descritos 258 casos na literatura mundial e no Brasil, doze casos. A HCM apresenta aumento da expressão do colágeno tipo IV e V e reduç
Publicado em: 2008
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8. Immunogenetics and infectious diseases: special reference to the mayor histocompatibility complex
Many studies have tried to identify genetic markers for infectious diseases, some of them have focused on human leukocyte antigens (HLA). The products of HLA genes interact with surface-specific receptors of T lymphocytes, resulting in activation of the host's immune response. Association of bacterial, viral, parasitic and fungal infections with the host's H
Brazilian Journal of Infectious Diseases. Publicado em: 2006-04
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9. Heterotopic transplantation of glycerin-preserved trachea: effect of respiratory epithelium desquamation on acute rejection
An effective preservation method and decreased rejection are essential for tracheal transplantation in the reconstruction of large airway defects. Our objective in the present study was to evaluate the antigenic properties of glycerin-preserved tracheal segments. Sixty-one tracheal segments (2.4 to 3.1 cm) were divided into three groups: autograft (N = 21),
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-07
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10. Antigen-Binding Specificity of Isolated Cell-Surface Immunoglobulin from Thymus Cells Activated to Histocompatibility Antigens
Lactoperoxidase-catalyzed radioiodination of cell-surface proteins was used in the isolation of cell-surface immunoglobulin from thymus-derived thoracic duct lymphocytes activated to histocompatibility-2 antigens. Immunoglobulin was identified by specific precipitation with antiserum to mouse immunoglobulin. Polyacrylamide gel electrophoresis of reduced and
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11. Histocompatibility antigens in coal miners with pneumoconiosis.
Twenty-five histocompatibility antigens have been measured in 100 coal miners with pneumoconiosis attending a pneumoconiosis medical panel and the results compared with a panel of 200 normal volunteers not exposed to dust. Chest radiographs were read independently by three readers according to the ILO U/C classification. On a combined score, 40 men were thou
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12. Major histocompatibility complex products restrict the adherence of cytolytic T lymphocytes to minor histocompatibility antigens or to trinitrophenyl determinants on schistosomula of Schistosoma mansoni.
We have previously shown that schistosomula passaged through mice acquire histocompatibility (H) antigens that can be recognized either by alloantibody or by alloreactive cytolytic T lymphocytes (CTL). The latter specifically adhere to but fail to damage the parasite. In this paper we describe the use of trinitrophenyl (TNP)-labeled schistosomula to show tha