High Performance Liquid Chromatographic
Mostrando 1-12 de 273 artigos, teses e dissertações.
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1. Evaluation of Antibacterial Activity, Chromatographic Analysis for Rutin and Quercetin Quantification Using HPLC-UV-Vis from the Hydro-Alcoholic Extract Obtained from Bidens pilosa Linné
Novel and miniaturized technique, a dynamic sonication-assisted solvent extraction before the analysis by high performance liquid chromatography-ultraviolet visible (HPLC-UV-Vis) for isolation, identification and quantification of rutin and quercetin metabolites in alcoholic extracts from Bidens pilosa Linné, was developed. The results showed that the flowe
J. Braz. Chem. Soc.. Publicado em: 2021-03
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2. Novo Qualis: rumos e rumores
Pharmaceutical cocrystals are composed of a drug and a coformer and are currently gaining attention due to their possibility of improving drug solubility. Quantitative determination of cocrystals is usually carried out by liquid chromatography method, but an alternative for the same is derivative UV spectrophotometry. Cocrystals of lamotrigine (LAM) were for
Rev. Bras. Hist.. Publicado em: 2020-12
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3. Development of a First-Order Derivative UV Spectrophotometric Method for the Assay and Solubility Evaluation of Lamotrigine and Nicotinamide Cocrystals
Pharmaceutical cocrystals are composed of a drug and a coformer and are currently gaining attention due to their possibility of improving drug solubility. Quantitative determination of cocrystals is usually carried out by liquid chromatography method, but an alternative for the same is derivative UV spectrophotometry. Cocrystals of lamotrigine (LAM) were for
J. Braz. Chem. Soc.. Publicado em: 2020-12
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4. Dereplication of Aporphine Alkaloids by UHPLC-HR-ESI-MS/MS and NMR from Duguetia lanceolata St. -Hil (Annonaceae) and Antiparasitic Activity Evaluation
Although the genus Duguetia is well known for producing alkaloids as chemical constituents, there are no reports of alkaloids identified in the species D. lanceolata. Thus, aiming to identify the chemical composition of this species, the dereplication of alkaloidic phase was performed by use of ultra-high performance liquid chromatography high resolution ele
J. Braz. Chem. Soc.. Publicado em: 2020-09
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5. SPECIATION ANALYSIS OF ARSENIC IN RICE USING HIGH PERFORMANCE LIQUID CHROMATOGRAPHY COUPLED WITH HYDRIDE GENERATION ATOMIC FLUORESCENCE SPECTROMETRY (HPLC-HG-AFS)
The aim of this work was to develop a method using high performance liquid chromatography coupled with hydride generation atomic fluorescence spectrometry (HPLC-HG-AFS) for the determination and speciation analysis of the inorganic and organic species of arsenic found most often in rice samples: As(V), As(III), monomethylarsonic acid (MMA), and dimethylarsin
Quím. Nova. Publicado em: 2020-06
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6. Methodology Development and Validation of Amphotericin B Stability by HPLC-DAD
The high worldwide consumption of antibiotics and their complex impurity profiles has drawn the attention of the scientific community to the development and validation of stability methods for these drugs. Amphotericin B is an antibiotic that is a natural fermentation product of bacterium Streptomyces nodosus, used as a broad-spectrum antifungal agent, and i
J. Braz. Chem. Soc.. Publicado em: 2020-05
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7. AVALIAÇÃO DE ADITIVOS DE FASE MÓVEL E TEMPERATURA NA VIDA ÚTIL DE COLUNAS PARA CROMATOGRAFIA LÍQUIDA DE ALTA EFICIÊNCIA
Buffered solutions, additives, and column temperature are widely used in high-performance liquid chromatography to promote adequate retention of compounds and to improve the chromatographic separation. However, these factors can dramatically reduce the column lifetime. In this work, the effect of column temperature, pH and the salt type and concentration in
Quím. Nova. Publicado em: 2020-03
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8. Application of a New Validated HPLC-PDA Method for Simultaneous Determination of Curcumin and Melatonin in Hyaluronic Acid-Coated Nanoemulsions
In this study, a high-performance liquid chromatography with photodiode array detector (HPLC-PDA) method was developed and validated to simultaneously determine curcumin (CUR) and melatonin (MEL) in hyaluronic acid-coated nanoemulsions, a novel targetable delivery system to CD44 receptors overexpressed in many types of tumors. Chromatographic analyses were p
J. Braz. Chem. Soc.. Publicado em: 2020-03
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9. Quantification of Glyphosate and AMPA by HPLC-ICP-MS/MS and HPLC-DAD: A Comparative Study
In this work, the direct determination methodology of glyphosate and aminomethylphosphonic acid (AMPA) by high performance liquid chromatography (HPLC) using inductively coupled plasma with triple quadrupole mass spectrometer (ICP-MS/MS) was compared with the conventional method using diode array detector (HPLC-DAD). Both methods were selective, but the chro
J. Braz. Chem. Soc.. Publicado em: 2020-02
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10. A newly validated HPLC–DAD-UV method to study the effects of medicinal plants extracts, fractions and isolate compounds on gastric emptying in rodents
Abstract In this study, we developed and validated a chromatographic method by High-performance Liquid Chromatography coupled to Diode-Array Ultraviolet Detector for quantification of acetaminophen in small volumes of plasma. This analytical method is particularly suitable for studies of gastric emptying time and pharmacokinetics in small rodents. Orally adm
Rev. bras. farmacogn.. Publicado em: 09/12/2019
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11. Synthesis of Hybrid Monolithic Columns Using a Click Chemistry Reaction for Application in Capillary Liquid Chromatography
Hybrid monolithic columns present characteristics of both silica and organic monoliths, such as good mechanical properties, wide pH tolerance, high permeability and stability and little swelling or shrinkage. A common way to prepare this type of material is by using alkoxysilanes and organic monomers via the sol-gel process and click chemistry reactions. In
J. Braz. Chem. Soc.. Publicado em: 24/10/2019
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12. Application of quality by design approach in RP-HPLC method development for simultaneous estimation of saxagliptin and dapagliflozin in tablet dosage form
A simple, sensitive, precise, accurate and robust high performance liquid chromatographic method has been developed for simultaneous estimation of saxagliptin (SAXA) and dapagliflozin (DAPA) in pharmaceutical formulation. Design of experiments (DoE) was applied for multivariate optimization of the experimental conditions of RP-HPLC method. Risk assessment wa
Braz. J. Pharm. Sci.. Publicado em: 24/10/2019