Quantification of Glyphosate and AMPA by HPLC-ICP-MS/MS and HPLC-DAD: A Comparative Study

AUTOR(ES)

Pimenta, Emanuella M.; Silva, Fabio F. da; Barbosa, Érica S.; Cacique, Ane P.; Cassimiro, Douglas L.; Pinho, Gevany P. de; Silvério, Flaviano O.

FONTE

J. Braz. Chem. Soc.

DATA DE PUBLICAÇÃO

2020-02

RESUMO

In this work, the direct determination methodology of glyphosate and aminomethylphosphonic acid (AMPA) by high performance liquid chromatography (HPLC) using inductively coupled plasma with triple quadrupole mass spectrometer (ICP-MS/MS) was compared with the conventional method using diode array detector (HPLC-DAD). Both methods were selective, but the chromatographic analysis using ICP-MS/MS as detector was four times faster than DAD. The methodology using ICP-MS/MS as detector was linear from 27 to 218 µg L-1, while by the conventional method it was 1 to 8 mg L-1. Detection limits of the glyphosate achieved with the HPLC-ICP-MS/MS and HPLC-DAD methods were 8.2 and 300 µg L-1, respectively. The direct determination using ICP-MS/MS as detector showed a lower number of stages in sample preparation because it did not need the derivatization step. Seven real samples were analyzed by HPLC-ICP-MS/MS and the results showed that these analytes were not detected.

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