Hemolysis Antioxidant
Mostrando 1-12 de 14 artigos, teses e dissertações.
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1. A Theoretical Antioxidant Mechanism for Cytoprotective Effect of p-Acetamide-Salicylate Derivatives against Free Radical Initiator AAPH in Human Erythrocytes
The molecular mechanism of cytoprotective effect on human erythrocytes of aminophenol and salicylates associated derivatives was related to their antioxidant capacity. The oxidative hemolysis induced by water-soluble free-radical initiator 2,2’-azobis-(2-amidine-propane)-dihydrochloride (AAPH) was inhibited by drug candidates named benzaminophen (BZL), sal
J. Braz. Chem. Soc.. Publicado em: 2021-07
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2. The role of seasonality on the chemical composition, antioxidant activity and cytotoxicity of Polish propolis in human erythrocytes
ABSTRACT Propolis extracts possess beneficial biological effects, such as antioxidant activity. However, the composition of propolis and biological properties of its extracts depend on many factor, including time of harvesting. The main purpose of this study was to evaluate the seasonal effect on the phenolic profile of Polish propolis extracts and their ant
Rev. bras. farmacogn.. Publicado em: 26/08/2019
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3. Characteristics of hemolytic activity induced by skin secretions of the frog Kaloula pulchra hainana
Background The hemolytic activity of skin secretions obtained by stimulating the frog Kaloula pulchra hainana with diethyl ether was tested using human, cattle, rabbit, and chicken erythrocytes. The skin secretions had a significant concentration-dependent hemolytic effect on erythrocytes. The hemolytic activity of the skin secretions was studied in the pre
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 18/04/2013
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4. Electron paramagnetic resonance study of lipid and protein membrane components of erythrocytes oxidized with hydrogen peroxide
Electron paramagnetic resonance (EPR) spectroscopy of spin labels was used to monitor membrane dynamic changes in erythrocytes subjected to oxidative stress with hydrogen peroxide (H2O2). The lipid spin label, 5-doxyl stearic acid, responded to dramatic reductions in membrane fluidity, which was correlated with increases in the protein content of the membran
Brazilian Journal of Medical and Biological Research. Publicado em: 2012-06
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5. Investigation of antioxidant and anti-glycation properties of essential oils from fruits and branchlets of Juniperus oblonga
Plants represent the best and most extensively studied source of natural antioxidants. The present study investigated the antioxidant and anti-glycation properties of different concentrations of essential oils obtained from fruits and branchlets of Juniperus oblonga M. Bieb., Cupressaceae, using different assays. The essential oils were obtained by steam dis
Rev. bras. farmacogn.. Publicado em: 12/04/2012
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6. Antioxidant activities of Juniperus foetidissima essential oils against several oxidative systems
The present study aimed to evaluate the antioxidant activity of essential oils obtained from branchlets of male and female trees as well as fruits of Juniperus foetidissima Willd., Cupressaceae, from Iran. For this purpose, essential oils of J. foetidissima were phytochemically analyzed and different concentrations of them were tested in five oxidative syste
Revista Brasileira de Farmacognosia. Publicado em: 08/07/2011
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7. ESTUDO QUÍMICO E BIOATIVIDADES DE Baccharis uncinella DC.
Baccharis uncinella (Asteraceae), popularmente conhecida como vassoura, é pouco conhecida do ponto de vista químico, havendo apenas dois trabalhos científicos anteriores sobre seus metabólitos secundários - os constituintes voláteis. No presente estudo, o óleo essencial das folhas de B.uncinella e nove extratos obtidos em Soxhlet com solventes orgâni
Publicado em: 2007
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8. Poliformismo da haptoglobina, status de ferro e proteinas de fase aguda em pacientes infectados pelo virus da imunodeficiencia humana (HIV)
Haptoglobin (Hp) is a plasma protein with antioxidant and immunomodulatory properties. Three main genotypes/phenotypes (Hp1-1, Hp2-1, Hp2-2) show distinctive efficiencies in their activities and have been related to susceptibility and/or outcome in different diseases, including HIV-infection. We compared the Hp genotype distribution between 387 Brazilian HIV
Publicado em: 2005
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9. Efeito da rutina em eritrocitos de ratos : estudo in vitro e in vivo
Many studies have investigated the ability of different compounds to protect biological systems from oxidative damage. In particular, flavonoids obtained from plants have been shown to inhibit reactions, whieh involve the produetion of radicais sueh as hidroxyl radical, and superoxide anion, as well as peroxyl and alkoxyl radicais. The antioxidant action of
Publicado em: 2001
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10. Targeted disruption of Nrf2 causes regenerative immune-mediated hemolytic anemia
A basic leucine zipper transcription factor, NF-E2-related factor 2 (Nrf2), plays a critical role in the cellular defense mechanism by mediating a coordinate up-regulation of antioxidant responsive element-driven detoxification and antioxidant genes. Here, we report that targeted disruption of Nrf2 causes regenerative immune-mediated hemolytic anemia due to
National Academy of Sciences.
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11. Thermal injury, intravascular hemolysis, and toxic oxygen products.
Acute thermal injury of rat skin produces an early, acute hemoglobinemia that is associated with the presence in blood of osmotically fragile red cells (RBC) that do not contain on their surfaces measurable amounts of complement components. The hemoglobinemia and the appearance in blood of osmotically fragile RBC appear to be the result of complement activat
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12. Involvement of oxidative damage in erythrocyte lysis induced by amphotericin B.
Lysis of human erythrocytes induced by amphotericin B was retarded when the oxygen tension of the incubation mixture was reduced or when the antioxidant catalase was added; lysis was accelerated when cells were preincubated with the prooxidant ascorbate. In the atmosphere of reduced oxygen tension, the erythrocytes containing carboxyhemoglobin lysed at a slo