Hamsters
Mostrando 25-36 de 888 artigos, teses e dissertações.
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25. The use of halloysite clay and carboxyl-functionalised multi-walled carbon nanotubes for recombinant LipL32 antigen delivery enhanced the IgG response
We studied the feasibility of using halloysite clay nanotubes (HNTs) and carboxyl-functionalised multi-walled carbon nanotubes (COOH-MWCNTs) as antigen carriers to improve immune responses against a recombinant LipL32 protein (rLipL32). Immunisation using the HNTs or COOH-MWCNTs significantly increased the rLipL32-specific IgG antibody titres (p < 0.05) of G
Mem. Inst. Oswaldo Cruz. Publicado em: 23/01/2015
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26. Cross-protection between experimental anti-leptospirosis bacterins
We investigated the existence of cross-protection between two anti-leptospirosis monovalent experimental bacterins produced with two strains of Leptospira serogroup Pomona: Fromm strain of serovar Kennewicky, isolated from pigs in the United States, and strain GR6 of serovar Pomona isolated from pigs in Brazil. Both were added of aluminum hydroxide as an adj
Braz. J. Microbiol.. Publicado em: 2014-09
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27. In vivo assessment of antiretroviral therapy-associated side effects
Antiretroviral therapy has been associated with side effects, either from the drug itself or in conjunction with the effects of human immunodeficiency virus infection. Here, we evaluated the side effects of the protease inhibitor (PI) indinavir in hamsters consuming a normal or high-fat diet. Indinavir treatment increased the hamster death rate and resulted
Mem. Inst. Oswaldo Cruz. Publicado em: 23/06/2014
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28. Protective microcirculatory and anti-inflammatory effects of heparin on endotoxemic hamsters
RESUMO OBJETIVO: Além de suas propriedades anticoagulantes, a heparina apresenta efeitos vasodilatadores e anti-inflamatórios que podem ajudar na reversão das alterações sépticas da microcirculação. Este artigo investiga os efeitos da heparina sobre alterações da microcirculação relacionadas com endotoxemia e compara-os com os observados com o u
MedicalExpress (São Paulo, online). Publicado em: 2014-06
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29. Antitumor activity of C-phycocyanin from Arthronema africanum (Cyanophyceae)
Pure C-phycocyanin (C-PC) was isolated from Arthronema africanumto evaluate its potential antitumor effects in vivo and in vitro. Experimental myeloid Graffi tumor in hamsters was used as a model. The cell proliferation assay showed that C-PC treatment, at concentration of 100 µg mL-1 for 24 h, significantly inhibited the growth of Graffi tumor cells (51.4%
Braz. arch. biol. technol.. Publicado em: 29/04/2014
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30. Padronização de um modelo de infecção por Clostridium difficile em hamsters sírios Mesocricetus auratus
O objetivo do presente trabalho foi padronizar um modelo de infecção por Clostridium difficile (ICD) em hamsters sírios (Mesocricetus auratus). Para seleção dos isolados capazes de causar letalidade, cinco animais por grupo receberam uma dose de clindamicina (30mg kg-1) por gavagem. Após 48 horas, administraram-se 107 unidades formadoras de colônia (U
Cienc. Rural. Publicado em: 2014
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31. Gender differences in microcirculation: Observation using the hamster cheek pouch
OBJECTIVES: Estrogen has been shown to play an important protective role in non-reproductive systems, such as the cardiovascular system. Our aim was to observe gender differences in vivo with regard to the increase in macromolecular permeability and leukocyte-endothelium interaction induced by ischemia/reperfusion as well as in microvascular reactivity to v
Clinics. Publicado em: 2013-12
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32. Peso como determinante da evolução clínica em hamsters (Mesocricetus auratus) infectados com Leishmania (Viannia) panamensis
RESUMO O resultado clínico da infecção por espécies de Leishmania do subgênero Viannia no modelo de hamster (Mesocricetus auratus) tem se mostrado diferente, dependendo do protocolo experimental. O peso corporal tem sido um importante determinante da evolução clínica da infecção em hamsters com leishmaniose visceral, mas sua importância como par�
Rev. Inst. Med. trop. S. Paulo. Publicado em: 2013-09
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33. Descrição morfológica e morfométrica da glândula vesicular de cobaias durante o desenvolvimento pós-natal
Glândulas vesiculares são essenciais para a reprodução, pois suas secreções afetam a função espermática. Cobaias (Cavia porcellus) são um excelente modelo experimental para estudo destas glândulas, contudo não existem dados morfológicos e morfométricos durante seu desenvolvimento. Neste estudo a morfologia (projeções das pregas (PP) e altura
Pesq. Vet. Bras.. Publicado em: 2013-07
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34. Effect of laser phototherapy in the prevention and treatment of chemo-induced mucositis in hamsters
The aim of this study was to investigate the effect of laser phototherapy (LPT) in the prevention and/or treatment of oral mucositis induced by 5-fluorouracil (5-FU; Eurofarma, São Paulo, Brazil) in hamsters. Ninety-six hamsters were divided into four groups (n = 24): Control (no treatment); Preventive [LPT from day (D) D-5 to D+5]; Therapeutic (LPT from D+
Braz. oral res.. Publicado em: 11/06/2013
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35. Ionic imbalance and lack of effect of adjuvant treatment with methylene blue in the hamster model of leptospirosis
Leptospirosis in humans usually involves hypokalaemia and hypomagnesaemia and the putative mechanism underlying such ionic imbalances may be related to nitric oxide (NO) production. We previously demonstrated the correlation between serum levels of NO and the severity of renal disease in patients with severe leptospirosis. Methylene blue inhibits soluble gua
Mem. Inst. Oswaldo Cruz. Publicado em: 2013-06
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36. Characterization of a virulent Leptospira interrogans strain isolated from an abandoned swimming pool
Pathogenic Leptospira spp. are the etiological agents of leptospirosis, an important disease of both humans and animals. In urban settings, L. interrogans serovars are the predominant cause of disease in humans. The purpose of this study was to characterize a novel Leptospira isolate recovered from an abandoned swimming pool. Molecular characterization throu
Braz. J. Microbiol.. Publicado em: 14/05/2013