Hamsters
Mostrando 13-24 de 888 artigos, teses e dissertações.
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13. Role of the route of leukotrienes in an experimental model of oral mucositis induced by 5-fluorouracil
Abstract Purpose: To investigate the participation of cysteinyl leukotrienes in the pathophysiology of oral mucositis. Methods: Oral mucositis was induced in hamsters using 5-fluorouracil (5-FU; 60 and 40 mg/kg; i.p., on days 1 and 2, respectively, and with excoriations in jugal mucosa on day 4). Montelukast (10, 20, or 40 mg/kg/d; gavage), MK886 (3 mg/kg/
Acta Cir. Bras.. Publicado em: 2017-09
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14. AFETO ENTRE HUMANOS E ANIMAIS NÃO HUMANOS NO BIOTÉRIO
O tema deste artigo são as relações de afeto entre humanos e animais não humanos em um contexto de prática científica: um biotério de uma instituição pública que abriga camundongos, hamsters e ratos para pesquisa. Os personagens centrais nesta narrativa são os animais e os técnicos do biotério. Estes últimos, quando relatam suas experiências c
Rev. bras. Ci. Soc.. Publicado em: 15/05/2017
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15. Tratamento tópico da leishmaniose cutânea experimental em golden hamsters (Mesocricetus auratus) com fórmulas contendo pentamidina
RESUMO O tratamento atual para Leishmaniose Tegumentar Americana é realizado com antimoniais pentavalentes como tratamento padrão, e as drogas de segunda escolha incluem pentamidina e anfotericina B, mas essas terapias apresentam efeitos colaterais e requerem administração parenteral. O objetivo deste trabalho foi avaliar formulações tópicas contendo
Acta Amaz.. Publicado em: 2017-03
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16. In vitro and in vivo antileishmanial activity of Artemisia annua L. leaf powder and its potential usefulness in the treatment of uncomplicated cutaneous leishmaniasis in humans
ABSTRACT INTRODUCTION: Cutaneous leishmaniasis (CL) is a tropical disease that affects millions of individuals worldwide. The current drugs for CL may be effective but have serious side effects; hence, alternatives are urgently needed. Although plant-derived materials are used for the treatment of various diseases in 80% of the global population, the valid
Rev. Soc. Bras. Med. Trop.. Publicado em: 2017-02
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17. In vitro antischistosomal activity of venom from the Egyptian snake Cerastes cerastes
Abstract INTRODUCTION: We studied the potential in vitro antischistosomal activity of Cerastes cerastes venom on adult Schistosoma mansoni worms. METHODS: Live specimens of the horned viper snake, C. cerastes were collected from the Aswan Governorate (Egypt). Venom was collected from snakes by manual milking. Worms of S. mansoni were obtained from infect
Rev. Soc. Bras. Med. Trop.. Publicado em: 2016-12
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18. Immune response in hamsters immunised with a recombinant fragment of LigA from Leptospira interrogans, associated with carrier molecules
Immunisation with the C-terminal region of leptospiral immunoglobulin-like A protein (LigANI) has shown promising results against leptospirosis. We evaluated the humoral immune response and protection induced by LigANI associated with carboxyl multi-walled carbon nanotubes (COOH-MWCNTs), CpG oligodeoxynucleotides (CpG ODNs), or Alhydrogel. Animals immunised
Mem. Inst. Oswaldo Cruz. Publicado em: 13/10/2016
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19. Effect of different anesthetic agents on left ventricular systolic function assessed by echocardiography in hamsters
Determination of left ventricular ejection fraction (LVEF) using in vivo imaging is the cardiac functional parameter most frequently employed in preclinical research. However, there is considerable conflict regarding the effects of anesthetic agents on LVEF. This study aimed at assessing the effects of various anesthetic agents on LVEF in hamsters using tran
Braz J Med Biol Res. Publicado em: 25/08/2016
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20. Prevenção da infecção por Clostridium difficile em hamsters usando uma estirpe não toxigênica
RESUMO: O presente trabalho objetivou a avaliação in vitro de cinco estirpes não toxigênicas de Clostridium difficile (NTCD) e seleção de uma delas para prevenção de infecção por C. difficile (CDI) em hamsters (Mesocricetus auratus ). As estirpes NTCD foram avaliadas quanto à produção de esporos in vitro, sensibilidade antimicrobiana e presenç
Cienc. Rural. Publicado em: 01/03/2016
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21. In vivo antileishmanial activity and chemical profile of polar extract from Selaginella sellowii
The polar hydroethanolic extract from Selaginella sellowii(SSPHE) has been previously proven active on intracellular amastigotes (in vitro test) and now was tested on hamsters infected with Leishmania (Leishmania) amazonensis (in vivo test). SSPHE suppressed a 100% of the parasite load in the infection site and draining lymph nodes at an intralesional dose o
Mem. Inst. Oswaldo Cruz. Publicado em: 19/02/2016
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22. Pesquisa utiliza microrganismo Clostridium difficile para prevenir infecções em hamsters
Cienc. Rural. Publicado em: 2016
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23. DNA prime-protein boost based vaccination with a conserved region of leptospiral immunoglobulin-like A and B proteins enhances protection against leptospirosis
Leptospirosis is a zoonotic disease caused by pathogenic spirochetes of theLeptospira genus. Vaccination with bacterins has severe limitations. Here, we evaluated the N-terminal region of the leptospiral immunoglobulin-like B protein (LigBrep) as a vaccine candidate against leptospirosis using immunisation strategies based on DNA prime-protein boost, DNA vac
Mem. Inst. Oswaldo Cruz. Publicado em: 11/12/2015
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24. Biological aspects of immature stage of Nyssomyia whitmani (Antunes and Coutinho) (Diptera, Psychodidae, Phlebotominae) in laboratory conditions
Nyssomyia whitmani (Antunes and Coutinho, 1939) has been considered as a complex of cryptic species, and some of the populations of this complex plays an important role in the transmission of Leishmania spp. in Brazil. The present study reports the biological aspects concerning the productivity out of eggs and the development time of the descendants of fema
Rev. Bras. entomol.. Publicado em: 2015-06