Glycogen Muscle Depletion
Mostrando 13-24 de 33 artigos, teses e dissertações.
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13. Motor units of juvenile rat lumbrical muscles and fibre type compositions of the glycogen-depleted component.
1. Fourth deep lumbrical muscles were dissected out, with their nerve supply, from juvenile rats aged 8-15 days (a period corresponding to maximal rate of decline of polyneuronal innervation), and aged 28, 29 and 30 days (when developmental synapse elimination is complete). Preparations were superfused with rat Ringer solution at 25 degrees C. 2. Isometric t
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14. Topographical projections of segmental nerves to the frog glutaeus muscle during loss of polyneuronal innervation.
The development of synaptic connexions to the frog (Limnodynastes tasmaniansis) glutaeus muscle from segmental nerves 8 and 9 was determined using glycogen depletion, contraction and electrophysiological methods between stages 54 and 60 (Nieuwkoop & Faber, 1975). There was no change in the number of muscle cells in the glutaeus from stage 55 onwards; the mat
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15. The muscle findings in the neuroleptic malignant syndrome associated with lysergic acid diethylamide.
A detailed pathological description of the muscle findings in a case of the neuroleptic malignant syndrome (NMS) following ingestion of lysergic acid diethylamide (LSD) is given, including the first ultrastructural analysis. Focal necrosis, oedema, and hypercontraction of fibres with glycogen and lipid depletion, were identified, all of which had resolved co
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16. Carbohydrate homeostasis and post-exercise ketosis in trained and untrained rats.
1. Experiments were carried out to establish what relationship there is between the concentration of ketone bodies in the blood and the concentrations of glycogen in muscle and liver of thirty-six trained and thirty-six untrained rats exercised at the same absolute load. There were, in addition, non-exercised control animals (of which thirty-six were trained
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17. The organization and development of compartmentalized innervation in rat extensor digitorum longus muscle.
1. We have examined the innervation of the rat extensor digitorum longus (EDL) muscle by the two extramuscular branches formed from the bifurcation of its muscle nerve. Observations of muscle contractions, recordings of end-plate potentials, and glycogen depletion of young adult muscles show that each branch innervates a separate region or 'compartment' in t
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18. The importance of competition between motoneurones in developing rat muscle; effects of partial denervation at birth.
1. The number of motor units in developing fourth deep lumbrical muscles was reduced by unilateral partial denervation of the muscle at birth, by cutting the lateral plantar nerve. A minority of the motor axons arrive via the sural nerve, and were thus not cut. Those muscles that contained one motor unit (one-unit muscles) after partial denervation developed
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19. The formation of topographical maps in developing rat gastrocnemius muscle during synapse elimination.
1. The rat lateral gastrocnemius muscle (LG) is a complex of four muscle compartments, each defined in terms of its unique innervation by a single primary nerve branch of the muscle nerve. A study has been made of the topographical distribution of motor units in the medial compartment of the LG (LGM) both before and after the loss of polyneuronal innervation
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20. Energy metabolism in single human muscle fibres during intermittent contraction with occluded circulation.
1. Glycogenolysis in type I and II muscle fibres was investigated in five healthy volunteers during electrical stimulation of the quadriceps muscle group with blood flow occluded. 2. The quadriceps femoris muscles were stimulated intermittently (1.6 s stimulation, 1.6 s rest) at a frequency of 50 Hz for 64 s and isometric contraction force was recorded. Musc
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21. Effect of Endotoxin on Pyruvate Kinase Activity in Mouse Liver
The pyruvate kinase (PK) activity of mouse liver increases after injection of endotoxin. It decreases in animals given cortisone alone and remains essentially unchanged in those given cortisone and endotoxin at the same time. CCl4 causes an increase in liver PK activity, but neither it nor endotoxin changes the activity of muscle PK. Addition of octonoate to
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22. Effect of endotoxin-induced monokines on glucose metabolism in the muscle cell line L6.
Exposure of fully differentiated L6 myotubes to a crude monokine preparation from endotoxin-stimulated RAW 264.7 cells resulted in a rapid and substantial (70%) increase in fructose 2,6-bisphosphate concentration coincident with a depletion of cellular glycogen and an increased lactate production. During the time required for glycogen depletion (3 hr), stimu
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23. Abnormalities in exercising skeletal muscle in congestive heart failure can be explained in terms of decreased mitochondrial ATP synthesis, reduced metabolic efficiency, and increased glycogenolysis.
OBJECTIVE: To distinguish between the effects of reduced oxidative capacity and reduced metabolic efficiency on skeletal muscle bioenergetics during exercise in patients with congestive heart failure. DESIGN AND PATIENTS: Patients were studied by 31P magnetic resonance spectroscopy during aerobic exercise and recovery, and results compared with controls. RES
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24. Effects of age on contractile and enzyme-histochemical properties of fast- and slow-twitch single motor units in the rat.
1. Contractile, enzyme-histochemical and morphometrical properties of muscle fibres were studied in single motor units of tibialis anterior (t.a.) and soleus muscles in young (3-6 months) and old (20-24 months) male albino rats. The technique of measuring glycogen depletion as a marker of previous muscle contraction was used for direct correlation of enzyme-