Genomics
Mostrando 13-24 de 915 artigos, teses e dissertações.
-
13. Nutritional and health benefits of legumes and their distinctive genomic properties
Abstract Legumes are indispensable for human diet in respect to their valuable and nutritive bioactive molecules. Legumes and derivative foodstuffs are rich in fiber, proteins, vitamins and some valuable phytochemicals, which exhibit important biological activities. Due to their remarkable molecular content, they are receiving great attention by researchers
Food Sci. Technol. Publicado em: 20/12/2018
-
14. Precision Medicine: Changing the way we think about healthcare
Health care has changed since the decline in mortality caused by infectious diseases as well as chronic and non-contagious diseases, with a direct impact on the cost of public health and individual health care. We must now transition from traditional reactive medicine based on symptoms, diagnosis and treatment to a system that targets the disease before it o
Clinics. Publicado em: 03/12/2018
-
15. Phylogenomic and single nucleotide polymorphism analyses revealed the hybrid origin of Spondias bahiensis (family Anacardiaceae): de novo genome sequencing and comparative genomics
Abstract The genus Spondias (family Anacardiaceae) comprises 19 taxa, ten of which occur in Neotropical regions. Spondias bahiensis has been suggested to be a hybrid, although initial evidence does not support this hypothesis. The aim of this study was to test the hypothesis of the hybrid origin of S. bahiensis using high-throughput sequencing with single nu
Genet. Mol. Biol.. Publicado em: 29/11/2018
-
16. Exploration of gene functions for esophageal squamous cell carcinoma using network-based guilt by association principle
Gene networks have been broadly used to predict gene functions based on guilt by association (GBA) principle. Thus, in order to better understand the molecular mechanisms of esophageal squamous cell carcinoma (ESCC), our study was designed to use a network-based GBA method to identify the optimal gene functions for ESCC. To identify genomic bio-signatures fo
Braz J Med Biol Res. Publicado em: 19/04/2018
-
17. Advances in Cryptococcus genomics: insights into the evolution of pathogenesis
Cryptococcus species are the causative agents of cryptococcal meningitis, a significant source of mortality in immunocompromised individuals. Initial work on the molecular epidemiology of this fungal pathogen utilized genotyping approaches to describe the genetic diversity and biogeography of two species, Cryptococcus neoformans and Cryptococcus gattii. Whol
Mem. Inst. Oswaldo Cruz. Publicado em: 19/02/2018
-
18. Comparative genomics of pathogenic Leptospira interrogans serovar Canicola isolated from swine and human in Brazil
Leptospira interrogans serovar Canicola is one of the most important pathogenic serovars for the maintenance of urban leptospirosis. Even though it is considered highly adapted to dogs, serovar Canicola infection has already been described in other animals and even a few human cases. Here, we present the genomic characterisation of two Brazilian L. interroga
Mem. Inst. Oswaldo Cruz. Publicado em: 2018-02
-
19. Efficient In Vitro Somatic Embryogenesis and Plant Regeneration from Mature and Immature Embryos of Wheat ( Triticum aestivum L.)
ABSTRACT An efficient regeneration system is a pre-requisite for the application of genetic transformation and functional genomics study of important plants. In this study, the effect of different factors (plant growth regulators, casein hydrolysate, aspartic acid and ascorbic acid) on in vitro embryogenesis and regeneration of Arta, Bahar and Zagros cultiva
Braz. arch. biol. technol.. Publicado em: 08/01/2018
-
20. Characterisation of a rare, reassortant human G10P[14] rotavirus strain detected in Honduras
BACKGROUND Although first detected in animals, the rare rotavirus strain G10P[14] has been sporadically detected in humans in Slovenia, Thailand, United Kingdom and Australia among other countries. Earlier studies suggest that the strains found in humans resulted from interspecies transmission and reassortment between human and bovine rotavirus strains. OB
Mem. Inst. Oswaldo Cruz. Publicado em: 2018-01
-
21. Draft genome sequence of phenol degrading Acinetobacter sp. Strain V2, isolated from oil contaminated soil
Abstract We report here the draft genome sequence of Acinetobacter sp. Strain V2 isolated from the oil contaminated soil collected from ENGEN, Amanzimtoti, South Africa. Degradation of phenolic compounds such as phenol, toluene, aniline etc. at 400 ppm in 24 h and oil degrading capability makes this organism an efficient multifunctional bioremediator. Genome
Braz. J. Microbiol.. Publicado em: 2017-06
-
22. Application of Next-generation Sequencing in Clinical Molecular Diagnostics
ABSTRACT Next-generation sequencing (NGS) is the catch all terms that used to explain several different modern sequencing technologies which let us to sequence nucleic acids much more rapidly and cheaply than the formerly used Sanger sequencing, and as such have revolutionized the study of molecular biology and genomics with excellent resolution and accuracy
Braz. arch. biol. technol.. Publicado em: 18/05/2017
-
23. The search for novel insecticide targets in the post-genomics era, with a specific focus on G-protein coupled receptors
Insects are considered pests globally, implicated in the destruction of agricultural fields and transmission of pathogens that cause deadly human diseases, such as dengue, Zika and malaria. The diversity of the insecticide arsenal has remained stagnant for decades, but the recent rise of insecticide resistance fueled the discovery of novel modes of action, a
Mem. Inst. Oswaldo Cruz. Publicado em: 2017-01
-
24. Value of genomics in breeding objectives for beef cattle
ABSTRACT The objective of this research was to discern the contribution of genomic information to multiple-trait breeding objectives and thus understand the economic value of that information. True genetic values were simulated for each of n, possibly correlated, traits. These true genetic values, combined with uncorrelated random noise, resulted in both gen
R. Bras. Zootec.. Publicado em: 2016-12