Genome Project
Mostrando 1-12 de 402 artigos, teses e dissertações.
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1. Nutritional genomics, inflammation and obesity
ABSTRACT The Human Genome Project has significantly broadened our understanding of the molecular aspects regulating the homeostasis and the pathophysiology of different clinical conditions. Consequently, the field of nutrition has been strongly influenced by such improvements in knowledge – especially for determining how nutrients act at the molecular leve
Arch. Endocrinol. Metab.. Publicado em: 2020-06
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2. Identification and validation of novel EST-SSR markers in olives
ABSTRACT: The olive (Olea europaea L.) is a leading oil crop in the Mediterranean area. Limited information on the inheritance of agronomic significant traits hinders progress in olive breeding programs, which encourages the development of markers linked to the traits. In this study, we report on the development of 46 olive simple sequence repeat (SSR) marke
Sci. agric. (Piracicaba, Braz.). Publicado em: 2017-06
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3. Evaluation of MC1R high-throughput nucleotide sequencing data generated by the 1000 Genomes Project
Abstract The advent of next-generation sequencing allows simultaneous processing of several genomic regions/individuals, increasing the availability and accuracy of whole-genome data. However, these new approaches may present some errors and bias due to alignment, genotype calling, and imputation methods. Despite these flaws, data obtained by next-generation
Genet. Mol. Biol.. Publicado em: 08/05/2017
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4. Analysis of the ergosterol biosynthesis pathway cloning, molecular characterization and phylogeny of lanosterol 14α-demethylase (ERG11) gene of Moniliophthora perniciosa
The phytopathogenic fungus Moniliophthora perniciosa (Stahel) Aime & Philips-Mora, causal agent of witches' broom disease of cocoa, causes countless damage to cocoa production in Brazil. Molecular studies have attempted to identify genes that play important roles in fungal survival and virulence. In this study, sequences deposited in the M. perniciosa Genome
Genet. Mol. Biol.. Publicado em: 03/11/2014
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5. Significant differe nces in demographic, clinical, and pathological features in relation to smoking and alcohol consumption among 1,633 head and neck cancer patients
OBJECTIVE: As a lifestyle-related disease, social and cultural disparities may influence the features of squamous cell carcinoma of the head and neck in different geographic regions. We describe demographic, clinical, and pathological aspects of squamous cell carcinoma of the head and neck according to the smoking and alcohol consumption habits of patients
Clinics. Publicado em: 2013-06
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6. Análise Integrativa de Perfis Transcricionais de Pacientes com Diabetes Mellitus Tipo 1, Tipo 2 e Gestacional, Comparando-os com Manifestações Demográficas, Clínicas, Laboratoriais, Fisiopatológicas e Terapêuticas / Integrative Analysis of Transcriptional Profiles in Type 1, Type 2 and Gestational Diabetes Mellitus, Compared with Demographic, Clinical, Laboratory, Physiopathology and Therapeutic Manifestations.
O diabetes mellitus tipo 1 (DM1) tem etiologia autoimune, enquanto o diabetes mellitus tipo 2 (DM2) e o diabetes mellitus gestacional (DMG) são considerados como distúrbios metabólicos. Neste trabalho, foi realizada análise do transcriptoma das células mononucleares do sangue periférico (do inglês, peripheral mononuclear blood cells - PBMCs), obtidas
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 09/03/2012
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7. Three decades of studies on chromosomal polymorphism of Drosophila willistoni and description of fifty different rearrangements
Drosophila willistoni (Insecta, Diptera) is considered a paradigm for evolutionary studies. Their chromosomes are characterized by multiple paracentric inversions that make it hard to identify and describe chromosomal poly-morphisms. In the present report we attempted to systematize the description of all the 50 inversions found in the last three decades, si
Genet. Mol. Biol.. Publicado em: 2012
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8. Expression analysis in response to drought stress in soybean: shedding light on the regulation of metabolic pathway genes
Metabolomics analysis of wild type Arabidopsis thaliana plants, under control and drought stress conditions revealed several metabolic pathways that are induced under water deficit. The metabolic response to drought stress is also associated with ABA dependent and independent pathways, allowing a better understanding of the molecular mechanisms in this model
Genetics and Molecular Biology. Publicado em: 2012
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9. Overall picture of expressed Heat Shock Factors in Glycine max, Lotus japonicus and Medicago truncatula
Heat shock (HS) leads to the activation of molecular mechanisms, known as HS-response, that prevent damage and enhance survival under stress. Plants have a flexible and specialized network of Heat Shock Factors (HSFs), which are transcription factors that induce the expression of heat shock proteins. The present work aimed to identify and characterize the Gl
Genetics and Molecular Biology. Publicado em: 2012
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10. Disauthorizing socially patterned suffering in patients suffering from neuromuscular diseases / Desautorizando o sofrimento socialmente padronizado, em pacientes afetados por doenças neuromusculares
From the results of the project (2006 to 2011) at the Psychoanalysis Clinic of the Human Genome Center at the University of São Paulo (USP), which gives priority to those suffering from neuromuscular diseases of genetic origin, we undertook a study whose hypothesis is that the diagnosis of a genetic change may act as an insult leaping upon at the patient (i
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 09/11/2011
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11. Molecular markers and genetic diversity of Plasmodium vivax
Enhanced understanding of the transmission dynamics and population genetics for Plasmodium vivax is crucial in predicting the emergence and spread of novel parasite phenotypes with major public health implications, such as new relapsing patterns, drug resistance and increased virulence. Suitable molecular markers are required for these population genetic stu
Memórias do Instituto Oswaldo Cruz. Publicado em: 2011-08
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12. The genome projects of the closely related cacao pathogens Moniliophthora roreri and Moniliophthora perniciosa.
The basidiomycetes Moniliophthora roreri and Moniliophthora perniciosa are the etiologic agents of the two most devastating diseases in cacao (Theobroma cacao ): frosty pod rot and the witches? broom, respectively. The species are very closely related and even hybrid cells have been previously obtained. In cacao, both species infect pods, causing necrosis, a
INTERNATIONAL CONFERENCE OF THE BRAZILIAN ASSOCIATION FOR BIOINFORMATICS AND COMPUTATIONAL BIOLOGY. Publicado em: 2011