Gene Networks
Mostrando 1-12 de 372 artigos, teses e dissertações.
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1. ASSESSMENT OF GIS-ASSISTED MOVEMENT PATCHES USING LCP FOR LOCAL SPECIES: NORTH CENTRAL ANATOLIA REGION, TURKEY
ABSTRACT As a result of the fragmentation and degradation of forests, the connectivity of natural habitats has been decreasing. Thus, problems in gene flow in wildlife have begun to arise. The connection of landscape patches with corridors is now an important subject of landscape planning. Central Anatolia has been affected by forest fragmentation due to its
CERNE. Publicado em: 2020-03
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2. Gene regulatory network inference and analysis of multidrug-resistant Pseudomonas aeruginosa
BACKGROUND Healthcare-associated infections caused by bacteria such as Pseudomonas aeruginosa are a major public health problem worldwide. Gene regulatory networks (GRN) computationally represent interactions among regulatory genes and their targets. They are an important approach to help understand bacterial behaviour and to provide novel ways of overcomi
Mem. Inst. Oswaldo Cruz. Publicado em: 05/08/2019
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3. Exploration of gene functions for esophageal squamous cell carcinoma using network-based guilt by association principle
Gene networks have been broadly used to predict gene functions based on guilt by association (GBA) principle. Thus, in order to better understand the molecular mechanisms of esophageal squamous cell carcinoma (ESCC), our study was designed to use a network-based GBA method to identify the optimal gene functions for ESCC. To identify genomic bio-signatures fo
Braz J Med Biol Res. Publicado em: 19/04/2018
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4. Excavation of attractor modules for nasopharyngeal carcinoma via integrating systemic module inference with attract method
The molecular mechanism of nasopharyngeal carcinoma (NPC) is poorly understood and effective therapeutic approaches are needed. This research aimed to excavate the attractor modules involved in the progression of NPC and provide further understanding of the underlying mechanism of NPC. Based on the gene expression data of NPC, two specific protein-protein in
Braz J Med Biol Res. Publicado em: 10/07/2017
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5. Comparisons Between Different Methods in Measuring Enzyme Similarity for Metabolic Network Alignment
Metabolic network alignments enable comparison of the similarities and differences between pathways in two metabolic networks and help to uncover the conserved sub-blocks therein. Such analysis is important in the understanding of metabolic networks and species evolution. The fundamental parts of metabolic network alignment algorithms all involve comparisons
Braz. arch. biol. technol.. Publicado em: 22/03/2016
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6. Gene expression profiling analysis of lung adenocarcinoma
The present study screened potential genes related to lung adenocarcinoma, with the aim of further understanding disease pathogenesis. The GSE2514 dataset including 20 lung adenocarcinoma and 19 adjacent normal tissue samples from 10 patients with lung adenocarcinoma aged 45-73 years was downloaded from Gene Expression Omnibus. Differentially expressed genes
Braz J Med Biol Res. Publicado em: 02/02/2016
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7. small ORFs: A new class of essential genes for development
Genes that contain small open reading frames (smORFs) constitute a new group of eukaryotic genes and are expected to represent 5% of the Drosophila melanogaster transcribed genes. In this review we provide a historical perspective of their recent discovery, describe their general mechanism and discuss the importance of smORFs for future genomic and transcrip
Genet. Mol. Biol.. Publicado em: 2015-09
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8. Identification of therapeutic target genes with DNA microarray in multiple myeloma cell line treated by IKKβ/NF-κB inhibitor
PURPOSE: To explore the mechanism of resistance to IKKβ inhibitor in multiple myeloma (MM) cells and uncover novel therapeutic targets for MM.METHODS: We downloaded the microarray data (GSE8476) from GEO (Gene Expression Omnibus) database. The data were derived from the human MM cells lines (L363 cells) treated with IKKβ inhibitor MLN120b (MLN) for eight,
Acta Cir. Bras.. Publicado em: 2014-11
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9. Expression analysis of miRNA and target mRNAs in esophageal cancer
We aimed to investigate miRNAs and related mRNAs through a network-based approach in order to learn the crucial role that they play in the biological processes of esophageal cancer. Esophageal squamous-cell carcinoma (ESCC) and adenocarcinoma (EAC)-related miRNA and gene expression data were downloaded from the Gene Expression Omnibus database, and different
Braz J Med Biol Res. Publicado em: 01/08/2014
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10. Identification of blood meal sources of Lutzomyia longipalpis using polymerase chain reaction-restriction fragment length polymorphism analysis of the cytochrome B gene
An analysis of the dietary content of haematophagous insects can provide important information about the transmission networks of certain zoonoses. The present study evaluated the potential of polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) analysis of the mitochondrial cytochrome B (cytb) gene to differentiate between vertebrat
Mem. Inst. Oswaldo Cruz. Publicado em: 07/05/2014
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11. Transduction motif analysis of gastric cancer based on a human signaling network
To investigate signal regulation models of gastric cancer, databases and literature were used to construct the signaling network in humans. Topological characteristics of the network were analyzed by CytoScape. After marking gastric cancer-related genes extracted from the CancerResource, GeneRIF, and COSMIC databases, the FANMOD software was used for the min
Braz J Med Biol Res. Publicado em: 04/04/2014
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12. Dinâmica da Fermentação Alcóolica: Aplicação de Redes Booleanas na Dinâmica de Expressão Gênica em Linhagens de Saccharomyces Cerevisiae durante o Processo Fermentativo / Dynamics of alcoholic fermentation: application of Boolean networks in the dynamics of gene expression in Saccharomyces cerevisiae strains during fermentation process
Na busca por soluções que maximizem a produção de etanol, o melhoramento genético de diferentes linhagens de levedura tornou-se foco de investigação em diversos centros de pesquisa. Com o recente sequenciamento de uma linhagem selvagem utilizada nas usinas sucroalcooleiras brasileiras, a linhagem PE-2 da espécie Saccharomyces cerevisiae, surgiu o int
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 17/10/2012