Gene Expression Profiling
Mostrando 13-24 de 507 artigos, teses e dissertações.
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13. Non-invasive messenger RNA transcriptional evaluation in human kidney allograft dysfunction
The aim of the present study was to evaluate messenger RNA expression in kidney allograft recipients. Forty-four kidney transplant recipients were evaluated up to three months after grafting. After transplantation, peripheral blood samples were drawn sequentially for real-time polymerase chain reaction analyses of perforin and TIM-3 genes. Biopsies were obta
Braz J Med Biol Res. Publicado em: 17/05/2018
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14. The Gene Ontology Differs in Bursa of Fabricius Between Two Breeds of Ducks Post Hatching by Enriching the Differentially Expressed Genes
ABSTRACT The bursa of Fabricius (BF) is the central humoral immune organ unique to birds. The present study investigated the possible difference on a molecular level between two duck breeds. The digital gene expression profiling (DGE) technology was used to enrich the differentially expressed genes (DEGs) in BF between the Jianchang and Nonghua-P strains of
Rev. Bras. Cienc. Avic.. Publicado em: 2018-03
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15. The catalase gene family in cucumber: genome-wide identification and organization
Abstract Catalase (CAT) is a common antioxidant enzyme in almost all living organisms. Currently, detailed reports on cucumber (Cucumis sativus L.) CAT (CsCAT) genes and tissue expression profiling are limited. In the present study, four candidate CsCAT genes were identified in cucumber. Phylogenetic analysis indicated that CsCAT1-CsCAT3 are closely related
Genet. Mol. Biol.. Publicado em: 25/07/2016
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16. Gene expression profiling analysis of lung adenocarcinoma
The present study screened potential genes related to lung adenocarcinoma, with the aim of further understanding disease pathogenesis. The GSE2514 dataset including 20 lung adenocarcinoma and 19 adjacent normal tissue samples from 10 patients with lung adenocarcinoma aged 45-73 years was downloaded from Gene Expression Omnibus. Differentially expressed genes
Braz J Med Biol Res. Publicado em: 02/02/2016
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17. Ropinirole alters gene expression profiles in SH-SY5Y cells: a whole genome microarray study
Ropinirole (ROP) is a dopamine agonist that has been used as therapy for Parkinson's disease. In the present study, we aimed to detect whether gene expression was modulated by ROP in SH-SY5Y cells. SH-SY5Y cell lines were treated with 10 µM ROP for 2 h, after which total RNA was extracted for whole genome analysis. Gene expression profiling revealed that 11
Braz J Med Biol Res. Publicado em: 19/01/2016
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18. Characteristics of dr1790 disruptant and its functional analysis in Deinococcus radiodurans
Deinococcus radiodurans (DR) is an extremophile that is well known for its resistance to radiation, oxidants and desiccation. The gene dr1790 of D. radiodurans was predicted to encode a yellow-related protein. The primary objective of the present study was to characterize the biological function of the DR1790 protein, which is a member of the ancient yellow/
Braz. J. Microbiol.. Publicado em: 2015-06
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19. Issues in solid-organ transplantation in children: translational research from bench to bedside
In this review, we identify important challenges facing physicians responsible for renal and cardiac transplantation in children based on a review of the contemporary medical literature. Regarding pediatric renal transplantation, we discuss the challenge of antibody-mediated rejection, focusing on both acute and chronic antibody-mediated rejection. We review
Clinics. Publicado em: 2014-01
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20. Transcriptional profiling of genes involved in n-hexadecane compounds assimilation in the hydrocarbon degrading Dietzia cinnamea P4 strain
The petroleum-derived degrading Dietzia cinnamea strain P4 recently had its genome sequenced and annotated. This allowed employing the data on genes that are involved in the degradation of n-alkanes. To examine the physiological behavior of strain P4 in the presence of n-alkanes, the strain was grown under varying conditions of pH and temperature. D. cinname
Braz. J. Microbiol.. Publicado em: 2013
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21. Overall picture of expressed Heat Shock Factors in Glycine max, Lotus japonicus and Medicago truncatula
Heat shock (HS) leads to the activation of molecular mechanisms, known as HS-response, that prevent damage and enhance survival under stress. Plants have a flexible and specialized network of Heat Shock Factors (HSFs), which are transcription factors that induce the expression of heat shock proteins. The present work aimed to identify and characterize the Gl
Genetics and Molecular Biology. Publicado em: 2012
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22. Micro RNA em adenocarcinoma de próstata: caracterização da expressão em tumores de baixo grau, órgão-confinados / Micro RNA in prostate adenocarcinoma : characterization of expression in low-grade tumors, organ-confined tumours
Introdução: Os micro RNA (miRNA) são formados a partir de RNA precursores de fita dupla que contém entre 60 a 110 nucleotídeos e formam estruturas do tipo hairpin. Imediatamente após sua transcrição pela RNA polimerase II a enzima Dicer promove a clivagem do RNA precursor em seqüências menores contendo 19 a 22 nucleotídeos. Após a clivagem, o miR
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 18/11/2011
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23. Perfil de expressão gênica de linfócitos T CD4+ na infecção pelo HTLV-1 / Gene expression profiling in CD4+ T-cells in HTLV-1 infection
O vírus linfotrópico de células T humanas tipo 1 (HTLV-1) está associado etiologicamente à duas principais manifestações clínicas: a leucemia/linfoma de células T do adulto (ATLL) e a mielopatia associada ao HTLV-1 ou paraparesia espástica tropical (HAM/TSP). Apenas 2 a 5% dos indivíduos infectados desenvolvem doenças associadas ao vírus, enquan
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 05/08/2011
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24. Gene trio signatures as molecular markers to predict response to doxorubicin cyclophosphamide neoadjuvant chemotherapy in breast cancerpatients
In breast cancer patients submitted to neoadjuvant chemotherapy (4 cycles of doxorubicin and cyclophosphamide, AC), expression of groups of three genes (gene trio signatures) could distinguish responsive from non-responsive tumors, as demonstrated by cDNA microarray profiling in a previous study by our group. In the current study, we determined if the expres
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-12