Fibrillogenesis
Mostrando 1-12 de 45 artigos, teses e dissertações.
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1. Ultrastructural and immunohistochemical studies of the uterine stroma in the decorin-deficient mice during pregnancy. / Estudo ultraestrutural e imunohistoquímico do estroma uterino durante a gestação de camundongos deficientes em decorim.
The present study is an ultrastructural investigation into the organization of collagen fibrils in the pregnant endometrium of wild-type and decorin-deficient mice. Our results showed that collagen fibrils from both genotypes present a great variability of shape and size in cross section. Significant variation in the diameter of collagen fibrils exists in th
Publicado em: 2009
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2. Changes in histoanatomical distribution of types I, III and V collagen promote adaptative remodeling in posterior tibial tendon rupture
INTRODUCTION: Posterior tibial tendon dysfunction is a common cause of adult flat foot deformity, and its etiology is unknown. PURPOSE: In this study, we characterized the morphologic pattern and distribution of types I, III and V collagen in posterior tibial tendon dysfunction. METHOD: Tendon samples from patients with and without posterior tibial tendon dy
Clinics. Publicado em: 2008
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3. Scleroderma-like remodeling induced by type V collagen / Remodelamento da pele semelhante à esclerodermia induzido pelo colágeno tipo V
Recentemente, descobrimos que coelhos, Nova Zelândia, imunizados com colágeno tipo V humano mais adjuvante de Freund apresentavam fibrose e vasculite de órgãos normalmente afetados na esclerose sistêmica. Deste modo, nós estudamos o processo de fibrilogênese para identificar possíveis fatores envolvidos na alteração do remodelamento observado neste
Publicado em: 2007
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4. Desenvolvimento do tendão elastico de aves : caracteristicas estruturais e aspectos ultra-estruturais relacionados a região elastica e a fibrocartilagem
Tendons are "usua11y suited for the transmission of mechanical forces from the musc1e of origin the bone of insertion. However, in many instances there are additionaI funCtiODS and properties difrering from the tendon ordinary anay, facing different biomechanical demands. The elastic tendon of the chicken wing has an elastic region that outspends to a large
Publicado em: 2002
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5. Effect of epithelial debridement on human cornea proteoglycans
Corneal transparency is attributed to the regular spacing and diameter of collagen fibrils, and proteoglycans may play a role in fibrillogenesis and matrix assembly. Corneal scar tissue is opaque and this opacity is explained by decreased ultrastructural order that may be related to proteoglycan composition. Thus, the objectives of the present study were to
Brazilian Journal of Medical and Biological Research. Publicado em: 2001-03
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6. Kinetic theory of fibrillogenesis of amyloid β-protein
Prior quasielastic light scattering (QLS) studies of fibrillogenesis of synthetic amyloid β-protein (Aβ)-(1–40) at low pH have suggested a kinetic model in which: (i) fibrillogenesis requires a nucleation step; (ii) nuclei are produced by Aβ micelles in addition to seeds initially present; and (iii) fibril elongation occurs by irreversible binding of A�
The National Academy of Sciences of the USA.
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7. Polyglutamine fibrillogenesis: The pathway unfolds
The National Academy of Sciences.
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8. Collagen fibrillogenesis: intermediate aggregates and suprafibrillar order.
Polymerization of collagen in vitro has been studied with the electron microscope at early time points of fibril assembly. We have found morphologically distinct stages of aggregation, which we suggest represent successive steps in fibril formation. Linear growth of the fibril appears to occur by the tandem addition of aggregates to each other and subsequent
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9. Progress in transthyretin fibrillogenesis research strengthens the amyloid hypothesis
The National Academy of Sciences.
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10. Frontiers of Matrix Biology. Volume 9. Epidermal Keratinocyte Differentiation and Fibrillogenesis
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11. Huntingtin aggregation monitored by dynamic light scattering
An initial stage of fibrillogenesis in solutions of glutathione S-transferase-huntingtin (GST-HD) fusion proteins has been studied by using dynamic light scattering. Two GST-HD systems with poly-l-glutamine (polyGln) extensions of different lengths (20 and 51 residues) have been examined. For both systems, kinetics of z-average translation diffusion coeffici
The National Academy of Sciences.
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12. Evolution of amyloid: What normal protein folding may tell us about fibrillogenesis and disease
The National Academy of Sciences.