Experimental Animal Models
Mostrando 1-12 de 329 artigos, teses e dissertações.
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1. Anatomical background of ovine kidney for use as animal model: analysis of arterial segmentation, proportional volume of each segment and arterial injury after cranial pole partial nephrectomy
ABSTRACT Objective To study the arterial segments of ovine kidney, present a proportional volume analysis of each kidney arterial segment, and analyze arterial injuries caused by simulated partial nephrectomy of cranial pole. Materials and Methods Forty-eight ovine kidneys injected with polyester resin into the renal arteries and collecting system were u
Int. braz j urol.. Publicado em: 2020-12
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2. Nuclear Medicine Methods for Assessment of Chronic Chagas Heart Disease
Abstract Several different imaging methods can be used to evaluate patients with Chagas heart disease (CHD) for diagnostic and prognostic purposes, including plain chest radiography; echocardiography; myocardial perfusion scintigraphy, for detection of ischemia and fibrosis; radionuclide gated-angiography, for evaluation of biventricular function; 123I-MIBG
Int. J. Cardiovasc. Sci.. Publicado em: 2020-12
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3. Healing effects of natural latex serum 1% from Hevea brasiliensis in an experimental skin abrasion wound model,
Abstract Background Dermabrasion is related with mechanical and surgical traumas on the skin; usually topical antiseptics and/or saline have been used for healing. Natural products for wound healing can also be used for abrasions, such as latex from Hevea brasiliensis. Objective This study aimed to evaluate the in vitro viability and migratory/proliferativ
An. Bras. Dermatol.. Publicado em: 2020-08
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4. Effects of growth hormone in the central nervous system
ABSTRACT Growth hormone (GH) is best known for its effect stimulating tissue and somatic growth through the regulation of cell division, regeneration and proliferation. However, GH-responsive neurons are spread over the entire central nervous system, suggesting that they have important roles in the brain. The objective of the present review is to summarize a
Arch. Endocrinol. Metab.. Publicado em: 10/01/2020
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5. Experimental models of scald burns. A scope review
Abstract Purpose: To conduct a scope review of the experimental model described by Walker and Mason, by identifying and analyzing the details of the method. Methods: The authors searched Pubmed-Medline, Cochrane-Bireme and PEDro databases for articles published between January 2016 and December 2018, using the following search queries: burns, burn injuries
Acta Cir. Bras.. Publicado em: 09/12/2019
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6. Effects of 1,25-dihydroxyvitamin D3 on experimental periodontitis and AhR/NF-κB/NLRP3 inflammasome pathway in a mouse model
Abstract Vitamin D has been known to have important regulatory functions in inflammation and immune response and shows inhibitory effects on experimental periodontitis in animal models. However, the potential mechanism has yet to be clarified. Recent studies have highlighted Aryl hydrocarbon receptor (AhR) and its downstream signaling as a crucial regulator
J. Appl. Oral Sci.. Publicado em: 04/11/2019
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7. Benefits of physical exercise on Parkinson’s disease disorders induced in animal models
Abstract Aim: The preventive and therapeutic role of physical exercise in Parkinson’s disease (PD) has been the target of study of many scientific groups, and the research often is done in experimental models, especially rodents. Thus, the aim of this review was to analyze a database, elucidating the main benefits that the systematized practice of physic
Motriz: rev. educ. fis.. Publicado em: 21/10/2019
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8. O papel da bioética nas comissões de ética animal
Resumo As diretrizes para usar animais como modelos experimentais transpuseram o campo bioético e chegaram ao âmbito jurídico. Se por um lado isso favoreceu a normatização de parâmetros físicos e biológicos voltados ao bem-estar animal, por outro, acrescentou demandas burocráticas que ocuparam a reflexão anteriormente destinada à resolução de co
Rev. Bioét.. Publicado em: 26/09/2019
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9. Anti-collagen type v: a marker of early systemic sclerosis?
Abstract Objective: To evaluate the frequency of anti-collagen type V in humans with early systemic sclerosis (SSc) compared to defined SSc patients and healthy controls, since collagen type V was shown to be overexpressed in early SSc patients’ skin and there is no data concerning the presence of this antibody in early stages of human SSc. Experimental s
Adv. rheumatol.. Publicado em: 29/07/2019
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10. Non-invasive ECG recording and QT interval correction assessment in anesthetized rats and mice
RESUMO: Ratos e camundongos são as espécies mais comumente utilizadas em estudos experimentais de eletrofisiologia cardíaca. O registro do eletrocardiograma (ECG) é de suma importância para o monitoramento de arritmias e função cardíaca em vários modelos de patologias. No entanto, a falta de valores de referência padronizados e a fórmula de corre�
Pesq. Vet. Bras.. Publicado em: 18/07/2019
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11. 18F-FDG PET/CT AS AN ASSESSMENT TOOL OF HEPATOCELLULAR CARCINOMA SECONDARY TO NON-ALCOHOLIC FATTY LIVER DISEASE DEVELOPMENT IN EXPERIMENTAL MODEL
RESUMO BACKGROUND: O carcinoma hepatocelular (CHC) pode ser a última fase da doença hepática gordurosa não alcoólica (DHGNA). Modelos experimentais são cruciais para elucidação da patogênese do CHC secundário a DHGNA. A tomografia por emissão de pósitrons/tomografia computadorizada (PET/TC) com 2-desoxi-2-(18F)fluoro-D-glicose (18F-FDG) desempe
Arq. Gastroenterol.. Publicado em: 18/03/2019
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12. Anti-inflammatory and antinociceptive effects of phonophoresis in animal models: a randomized experimental study
The aim of this study was to evaluate the therapeutic effects of ultrasound (US)-mediated phonophoresis alone or in association with diclofenac diethylammonium (DCF) administered topically in animal models of inflammation. A pre-clinical, prospective, and randomized experimental study of quantitative and qualitative nature was carried out. Phonophoresis was
Braz J Med Biol Res. Publicado em: 24/01/2019