Epigenetics
Mostrando 13-24 de 38 artigos, teses e dissertações.
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13. Alterações epigenéticas do gene p16 em ratos tratados com altas doses de I-metionina / Epigenetics changes of the p16 gene in rats treated with high doses of lmethionine
Several evidences suggest that to diet is a relevant factor in modifying the risks of developing cancer and the nutrient-genome interaction has a significant influence for the maintenance of a good health condition. Nutrigenomic establishes a relation between to diet and the investigation of epigenetic DNA modifications, which may play an important role in t
Publicado em: 2009
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14. Epigenetic targets in the diagnosis and treatment of prostate cancer
Prostate cancer (PC) is one of leading cause of cancer related deaths in men. Various aspects of cancer epigenetics are rapidly evolving and the role of 2 major epigenetic changes including DNA methylation and histone modifications in prostate cancer is being studied widely. The epigenetic changes are early event in the cancer development and are reversible.
International braz j urol. Publicado em: 2007-02
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15. In silico characterization and epigenetic analysis of in vivo and cloned cattle of the homologue region 11p15.5 involved with Beckwith-Wiedemann syndrome in humans / Caracterização in silico e análise epigenética em bovinos produzidos in vivo e por transferência nuclear da região homóloga à 11p15.5 envolvida com a síndrome de Beckwith-Wiedemann em humanos
Epigenetics is the branch of biology which studies heritable changes in genome function that occur without a change in nucleotide sequence within the DNA. One of the most studied epigenetic process is the DNA methylation, which is associated with several gene regulation mechanisms such as genomic imprinting. This type of regulation is characterized by parent
Publicado em: 2007
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16. The prima donna of epigenetics: the regulation of gene expression by DNA methylation
This review focuses on the mechanisms of DNA methylation, DNA methylation pattern formation and their involvement in gene regulation. Association of DNA methylation with imprinting, embryonic development and human diseases is discussed. Furthermore, besides considering changes in DNA methylation as mechanisms of disease, the role of epigenetics in general an
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-10
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17. The genetic study of sterigmatocystin production in Aspergillus nidulans. / Estudo genético da produção de esterigmatocistina em Apergillus nidulans.
Sterigmatocystin (ST) is a polyketide produced by different species of Aspergillus as well as by other fungus genera such as Bipolaris and Chaetomium. This toxin is characterized as a bifuranoxanthone, whose molecular formula is C18H12O6 and which is frequently found as a contaminant in several food products such as oil-seed grains and cereals. It has carcin
Publicado em: 1999
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18. Cancer epigenetics takes center stage
The National Academy of Sciences.
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19. Epigenetics and its role in disease
American Society for Clinical Investigation.
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20. Epigenetics: A Molecular Link Between Environmental Factors and Type 2 Diabetes
American Diabetes Association.
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21. Rett Syndrome and MeCP2: Linking Epigenetics and Neuronal Function
The American Society of Human Genetics.
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22. Decoding the epigenetic effects of chromatin
A report on the Alan Wolffe EMBO Workshop on 'Chromatin and Epigenetics', Heidelberg, Germany, 19-22 June 2003.
BioMed Central.
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23. The epigenetics of the cell
A report on the 42nd Annual Meeting of the American Society for Cell Biology, San Francisco, 14-18 December 2002.
BioMed Central.
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24. Epigenetics: intrauterine growth retardation (IUGR) modifies the histone code along the rat hepatic IGF-1 gene
Intrauterine growth restriction (IUGR) decreases serum insulin growth factor-1 (IGF-1) levels. IGF-1 is an epigenetically regulated gene that has two promoters, alternative exon 5 splicing, and multiple termination sites. The regulation of gene expression involves the whole gene, as evidenced by the aforementioned IGF-1 paradigm. We hypothesized that IUGR in
The Federation of American Societies for Experimental Biology.