Endogenous Fertility
Mostrando 1-12 de 23 artigos, teses e dissertações.
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1. Star anise extracts modulation of reproductive parameters, fertility potential and DNA fragmentation induced by growth promoter Equigan in rat testes
ABSTRACT Equigan is an anabolic steroid that has been developed for veterinary use and derived from endogenous sex hormone testosterone that plays a key role in the development of male reproductive tissue as well as in puberty and spermatogenesis. The current study is aimed to investigate the possible prophylactic effect of star anise extracts (SAE) on the t
Braz. J. Pharm. Sci.. Publicado em: 07/06/2018
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2. Morfofisiologia do sistema genital masculino de ratos púberes e adultos após privação androgênica durante a pré-puberdade / Morphophysiology of male reproductive system of adult and pubertal rats after androgen deprivation during prepuberty
Endocrine disrupters are chemicals that can act as agonists or antagonists of endogenous hormones, interfering with the homeostasis of the organism. Since the endocrine system plays a critical role in the development and function of the male reproductive system, this is an especially vulnerable target of potential endocrine perturbations. The literature pres
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 06/02/2012
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3. Serà que os programas sociais de reduÃÃo do trabalho infantil proporcionam mobilidade social?
Essa dissertaÃÃo investiga quais os efeitos dos programas sociais de combate ao trabalho infantil sobre o ganho educacional das crianÃas, sobre a pobreza e sobre a desigualdade. Para tanto, desenvolveu-se um modelo de geraÃÃes sobrepostas de indivÃduos que diferem quanto à sua dotaÃÃo de capital humano. Determina-se que os indivÃduos do tipo h3, os
Publicado em: 2006
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4. Estrogen-Dependent and -Independent Estrogen Receptor-α Signaling Separately Regulate Male Fertility
Estrogen receptor-α (ERα) plays a critical role in male reproductive tract development and fertility. To determine whether estrogen-dependent and -independent ERα mechanisms are involved in male fertility, we examined male estrogen nonresponsive ERα knock-in mice. These animals have a point mutation (G525L) in the ligand-binding domain of ERα that signi
The Endocrine Society.
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5. Instructing an Embryonic Stem Cell-Derived Oocyte Fate: Lessons from Endogenous Oogenesis
Female reproductive potential is limited in the majority of species due to oocyte depletion. Because functional human oocytes are restricted in number and accessibility, a robust system to differentiate oocytes from stem cells would enable a thorough investigation of the genetic, epigenetic, and environmental factors affecting human oocyte development. Also,
The Endocrine Society.
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6. Reduced Fertility in Male Mice Deficient in the Zinc Metallopeptidase NL1
Members of the M13 family of zinc metalloendopeptidases have been shown to play critical roles in the metabolism of various neuropeptides and peptide hormones, and they have been identified as important therapeutic targets. Recently, a mouse NL1 protein, a novel member of the family, was identified and shown to be expressed mainly in the testis as a secreted
American Society for Microbiology.
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7. Overexpression of 20-Oxidase Confers a Gibberellin-Overproduction Phenotype in Arabidopsis
In the gibberellin (GA) biosynthesis pathway, 20-oxidase catalyzes the oxidation and elimination of carbon-20 to give rise to C19-GAs. All bioactive GAs are C19-GAs. We have overexpressed a cDNA encoding 20-oxidase isolated from Arabidopsis seedlings in transgenic Arabidopsis plants. These transgenic plants display a phenotype that may be attributed to
American Society of Plant Physiologists.
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8. Restorer genes for different forms of Brassica cytoplasmic male sterility map to a single nuclear locus that modifies transcripts of several mitochondrial genes
The oilseed rape plant, Brassica napus, possesses two endogenous male sterile cytoplasms, nap and pol. Previous studies have shown that nuclear restoration of pol cytoplasmic male sterility (CMS) is conditioned by a gene, Rfp, that is also involved in modifying transcripts of the pol CMS-associated orf224/atp6 mtDNA region. We now find that the nap nuclear r
The National Academy of Sciences.
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9. The Arabidopsis DIMINUTO/DWARF1 gene encodes a protein involved in steroid synthesis.
We have identified the function of the Arabidopsis DIMINUTO/DWARF1 (DIM/DWF1) gene by analyzing the dim mutant, a severe dwarf with greatly reduced fertility. Both the mutant phenotype and gene expression could be rescued by the addition of exogenous brassinolide. Analysis of endogenous sterols demonstrated that dim accumulates 24-methylenecholesterol but is
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10. Antiprogestins prevent progesterone receptor binding to hormone responsive elements in vivo.
Antiprogestins inhibit progesterone action by competing for binding to the progesterone receptor and are potentially important pharmaceuticals in fertility control and cancer therapy. Why the complex of antiprogestins and progesterone receptor is functionally inactive is unclear. Present models are based on indirect evidence, such as transfection competition
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11. Estrogen Promotes Germ Cell and Seminiferous Tubule Development in the Baboon Fetal Testis1
The foundation for development of the male reproduction system occurs in utero, but relatively little is known about the regulation of primate fetal testis maturation. Our laboratories have shown that estrogen regulates key aspects of the physiology of pregnancy and fetal development. Therefore, in the present study, we characterized and quantified germ cell
Society for the Study of Reproduction.
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12. A Unique Short-Chain Dehydrogenase/Reductase in Arabidopsis Glucose Signaling and Abscisic Acid Biosynthesis and Functions
Glc has hormone-like functions and controls many vital processes through mostly unknown mechanisms in plants. We report here on the molecular cloning of GLUCOSE INSENSITIVE1 (GIN1) and ABSCISIC ACID DEFICIENT2 (ABA2) which encodes a unique Arabidopsis short-chain dehydrogenase/reductase (SDR1) that functions as a molecular link between nutrient signaling and
American Society of Plant Biologists.