Embryonic Stem Cell
Mostrando 13-24 de 682 artigos, teses e dissertações.
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13. Caracterização do papel das proteínas quinases C (PKCs) na proliferação e auto-renovação das células tronco embrionárias murinas / Characterization of the role of protein kinases C (PKC) in proliferation and self-renewal of murine embryonic stem cells
Células tronco embrionárias (CTE) são capazes de proliferar indefinidamente mantendo a sua pluripotência, isto é, a capacidade de se diferenciar em diversos tipos celulares perante estímulos adequados. Esse potencial tem sido intensamente estudado, de modo a permitir a utilização dessas células em terapias de reposição celular. Trabalhos anteriore
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 04/08/2011
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14. Proteção da vida humana embrionária e repercussão no campo jurídico e ambiental
O avanço da ciência, em especial na área da reprodução humana, permitiu a ocorrência de concepção humana de forma extracorpórea através do processo de fecundação in vitro a ser feita em laboratório especializado em reprodução humana assistida. Os embriões não implantados em útero materno são criopreservados. Este trabalho busca trazer os q
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/04/2011
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15. Embryonic stem-like cells derived from in vitro produced bovine blastocysts
The aim of this work was to study the derivation of bovine embryonic stem-like (ES-like) cells from the inner cell mass (ICM) of in vitro produced blastocysts. The ICMs were mechanically isolated and six out of seventeen (35%) ICMs could attach to a monolayer of murine embryonic fibroblasts (MEF). Ten days after, primary outgrowths were mechanically dissecte
Brazilian Archives of Biology and Technology. Publicado em: 2011-06
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16. Mouse embryonic stem cells: the establishment of the system to produce differentiated cell types in vitro
During the last few years, embryonic stem (ES) cells have been a new tool in cell biology which is very promising for the scientific community to develop new cell therapies. ES cells are the only cell type that can differentiate into derivates of the three primary germ layers, not only in vivo but also, and most important, in vitro. This so-called pluripoten
Publicado em: 2010
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17. In vitro differentation of embryonic stem cells into cardiac-like and neuronal-like cells
Células-tronco embrionárias são linhagens celulares pluripotentes capazes de se multiplicar indefinidamente e com grande capacidade de diferenciação celular. São isoladas de embriões em estágio pré-implantacional e podem ser cultivadas por longo tempo em laboratório sem perder sua pluripotencialidade. Células-tronco embrionárias podem, ainda, se
Publicado em: 2010
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18. Células-Tronco / Stem cells
Considerando a origem de obtenção, as células-tronco podem ser classificadas como células-tronco embrionárias (ES) ou como células-tronco adultas. Mas, se a plasticidade for considerada, as células-tronco podem ser classificadas como células totipotentes, quando as células-tronco preservam a capacidade de dar origem a um novo indivíduo completo. Qu
Publicado em: 2010
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19. Reduced transcription of TCOF1 in adult cells of Treacher Collins syndrome patients
Background: Treacher Collins syndrome (TCS) is an autosomal dominant craniofacial disorder caused by frameshift deletions or duplications in the TCOF1 gene. These mutations cause premature termination codons, which are predicted to lead to mRNA degradation by nonsense mediated mRNA decay (NMD). Haploinsufficiency of the gene product (treacle) during embryoni
Publicado em: 2010
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20. Successful scale-up of human embryonic stem cell production in a stirred microcarrier culture system
Future clinical applications of human embryonic stem (hES) cells will require high-yield culture protocols. Currently, hES cells are mainly cultured in static tissue plates, which offer a limited surface and require repeated sub-culturing. Here we describe a stirred system with commercial dextran-based microcarriers coated with denatured collagen to scale-up
Brazilian Journal of Medical and Biological Research. Publicado em: 2009-06
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21. Pesquisa de células-tronco humanas e a efetividade do direito à vida / Stem cell research and the effectiveness of the human right to life
This study aims to present a discussion of research on the constitutional nature of human stem cells. It started to approach the theme with the elucidation of the difference between language and language to get the constitutional interpretation with emphasis on fundamental rights, and last about a stem cell research with a look of bioethics. Among these fund
Publicado em: 2009
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22. Comparative study of ribosomal genes activity in leukocytes and gingival tissues from Down syndrome individuals, in relation to age. / Estudo comparativo da atividade dos genes ribossômicos em mucosa bucal (gengiva) e leucócitos de indivíduos com Síndrome de Down em relação à idade.
Cytogenetic and molecular studies have shown significant reduction in the ribosomal genes activity in lymphocyte and fibroblasts cells from older Trisomy 21 or Down syndrome (DS) individuals as well as in lymphocyte and neural cortical cells from Alzheimers disease patients. We have proposed the study of rRNA levels in older and younger DS subjects in two di
Publicado em: 2009
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23. Stem cell grafts as therapeutic tools for central nervous system disorders
The last few years have seen a growing interest in stem cell research. The media has helped to keep attention to the subject making it as popular as therapeutic cloning. A number of studies highlighted the importance of stem cells as prospective therapy for neurodegenerative conditions. The possibility of successful treatment for such pathologies using stem
Psychology & Neuroscience. Publicado em: 2008-06
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24. Uso de matriz extracelular (Matrigel®) para estabelecimento de cultivo de células-tronco embrionárias de suínos e caracterização da expressão de moléculas associadas à pluripotência / Use of extracellular matrix (Matrigel®) for establishment of porcine embryonic stem cells and expression characterization of plurpotency related molecules
Establishment of embryonic stem cell (ESC) culture in pigs has not been achieved. Verification of pluripotency markers and differentiation in the three embryonic layers are necessary for validation of a pluripotent cell line. The objective of this study was to establish and characterize porcine ESC culture using Matrigel and compare the expression of pluripo
Publicado em: 2008