Dna Integrity
Mostrando 1-12 de 627 artigos, teses e dissertações.
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1. Telomere length: biological marker of cellular vitality, aging, and health-disease process
SUMMARY The aging process occurs due to the decline of vital physiological functions and adaptability of the body, being influenced by genetics and lifestyle. With advances in genetics, biological aging can be calculated by telomere length. Telomeres are regions at the ends of chromosomes that play a role in the maintenance and integrity of DNA. With biologi
Rev. Assoc. Med. Bras.. Publicado em: 2021-02
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2. Bubaline Diaphragm Matrix: Development and Clinical Assessment into Cattle Abdominal Hernia Repair
Abstract The purpose of the study was to develop a xenogenic bubaline diaphragm matrix (BDM) for abdominal hernia repair. A fresh diaphragm was decellularized using aqueous sodium dodecyl sulfate (SDS) solutions (0.5-4% w/v) over a period. Acellularity was confirmed histologically and characterized by Masson’s trichrome staining, scanning electron microsc
Braz. arch. biol. technol.. Publicado em: 25/11/2019
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3. Characterization of Decellularized Human Pericardium for Tissue Engineering and Regenerative Medicine Applications
Resumo Fundameto: O enxerto de pericárdio pode ser usado em muitos procedimentos de correção cirúrgica. Uma das estratégias da engenharia tecidual é o processo de descelularização. No entanto, embora esse processo diminua a resposta imunogênica, a descelularização pode modificar tanto o comportamento como a composição da matriz extracelular nat
Arq. Bras. Cardiol.. Publicado em: 27/06/2019
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4. Efeito da adição de plasma seminal oriundo de animais de alta e baixa fertilidade na criopreservação de espermatozoides da cauda do epidídimo e do ejaculado de garanhões subférteis
RESUMO O objetivo do presente estudo foi avaliar o efeito da adição de plasma seminal de garanhões de alta e baixa fertilidade sobre a congelabilidade e a viabilidade de espermatozoides do ejaculado (EJ) e do epidídimo (EP) de garanhões subférteis. Foram utilizados seis garanhões com histórico de subfertilidade. Após coleta, espermatozoides do ejacu
Arq. Bras. Med. Vet. Zootec.. Publicado em: 14/06/2019
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5. DNA de alta qualidade isolado a partir do córtex de Euterpe edulis Mart. (Arecaceae)
Resumo Euterpe edulis (palmiteiro-juçara) é uma arbórea de porte alto que ocorre naturalmente em florestas da Mata Atlântica e Cerrado. Por estas características é difícil coletar folhas jovens, sadias e frescas para obtenção de DNA genômico de boa qualidade para a espécie, necessárias para estudos de biologia molecular. Visando facilitar coletas
Ciênc. Florest.. Publicado em: 30/05/2019
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6. Folate and Cancer: Is There Any Association?
Abstract Folate plays a central role in DNA synthesis and methylation, which are essential for DNA integrity maintenance and gene expression. Folate deficiency may lead to the incorporation of uracil into DNA and chromosome breaks, increasing the risk of cancer. However, conflicting evidence has been observed depending on the type of epidemiological study, d
J. inborn errors metab. screen.. Publicado em: 30/05/2019
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7. The effects of xanthan gum on equine sperm quality during cooling storage
RESUMO Esse estudo foi desenvolvido para avaliar os possíveis benefícios de acrescentar xanthan gum a um extensor padrão através de analises in vitro de qualidade de esperma. Semen foi coletado quatro vezes de cinco garanhões diferentes (n = 20 amostras) e submetido a armazenamen to resfriado em diferentes condições: controle (apenas extensor padrão)
Arq. Bras. Med. Vet. Zootec.. Publicado em: 2019-02
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8. Methylation of p16 ink4a promoter is independent of human papillomavirus DNA physical state: a comparison between cervical pre-neoplastic and neoplastic samples
BACKGROUND Epigenetic modifications in host cells, like p16 ink4a methylation, have been considered as putative complementary mechanisms for cancer development. Because only a small proportion of infected women develop cervical cancer, other factors might be involved in carcinogenesis, either independently or in association with high-risk human papillomavir
Mem. Inst. Oswaldo Cruz. Publicado em: 17/12/2018
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9. An association study of FOXO3 variant and longevity
Abstract Human longevity is a polygenic and multifactorial trait. Pathways related to lifespan are complex and involve molecular, cellular, and environmental processes. In this analytical observational study, we evaluated the relationship between environment factors, oxidative stress status, DNA integrity level, and the association of FOXO3 (rs2802292), SOD2
Genet. Mol. Biol.. Publicado em: 11/06/2018
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10. Circulating cell-free DNA as a biomarker in the diagnosis and prognosis of colorectal cancer
Abstract Colorectal cancer (CRC) is a disease without evident clinical symptoms in early stages, leading to late diagnosis and disease management. Current diagnostic and prognostic tools require invasive procedures and circulating molecular biomarkers fail to have optimal sensitivity and specificity. Circulating biomarkers with high clinical performance may
Braz. J. Pharm. Sci.. Publicado em: 07/06/2018
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11. The role of fetal-maternal microchimerism as a natural-born healer in integrity improvement of maternal damaged kidney
ABSTRACT Purpose: To identify the fetal stem cell (FSC) response to maternal renal injury with emphasis on renal integrity improvement and Y chromosome detection in damaged maternal kidney. Materials and Methods: Eight non-green fluorescent protein (GFP) transgenic Sprague-Dawley rats were mated with GFP-positive transgenic male rats. Renal damage was indu
Int. braz j urol.. Publicado em: 2018-06
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12. Analysis of E2 gene integrity in HPV16 and HPV58 viruses isolated from women with cervical pathology
Integration of human papillomavirus (HPV) DNA into human cells accompanied by the disruption of the viral genome has been described as a prerequisite for cancer development. This study aimed to investigate E2 gene integrity of HPV16 and HPV58 viruses isolated from infected women with cervical lesions. Forty-two HPV16- and 31 HPV58-positive samples were analy
Mem. Inst. Oswaldo Cruz. Publicado em: 31/10/2016