Dimethyldioxirane
Mostrando 1-3 de 3 artigos, teses e dissertações.
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1. Oxone®-Mediated Direct α-Hydroxylation of β-Dicarbonyl Compounds: Racemic Synthesis of Harzialactone A
An environmentally benign method is described for the α-hydroxylation of malonates and cyclic analogues in aqueous medium at room temperature under mild conditions, based on the in situ generation of dimethyldioxirane through the combination of acetone and Oxone®. This procedure was found to be substrate-dependent and was successfully performed to provide
J. Braz. Chem. Soc.. Publicado em: 12/08/2019
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2. Synthesis of Spiro-Pyrrolidinyloxindoles by Oxidative Rearrangement of N-Acyltetrahydro-β-carbolines Using an Oxone/Aqueous Acetone Mixture
Spiro-pyrrolidinyl-2-oxindoles were prepared by the oxidative rearrangement of Na-acetyl-1,2,3,4-tetrahydro-β-carbolines (THBC) using dimethyldioxirane generated in situ. The Na-acetyl THBC substrates were obtained by Pictet-Spengler and acyl-Pictet-Spengler reactions of L-tryptophan methyl ester, followed by Na-acetylation. The stereoselectivity of the oxi
J. Braz. Chem. Soc.. Publicado em: 2019-01
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3. Ciclofuncionalização de β,-enamino Ésteres e β-hidróxi ésteres / Electrophilic cyclization of alkenyl-substituted β-enamine esters and β-hydroxy esters
Nosso grupo de pesquisa vem se dedicado, há vários anos, ao estudo das reações de ciclização eletrofílica de substratos insaturados que contêm um nucleófilo interno (oxigênio ou nitrogênio). Este trabalho teve como objetivo obter derivados de éteres cíclicos de cinco e seis membros diferentemente funcionalizados. Compostos 1,3-dicarbonílicos e
Publicado em: 2002